The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
SC-560 - 10mM in DMSO, high purity , CAS No.188817-13-2
Highly selective COX-1 inhibitor
Basic Description Synonyms SC-560|188817-13-2|5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole|SC 560|SC560|5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole|5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole|CHEMBL26915|CHEBI:76 Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms SC 560 is reported to be a Cox-1 and Cox-2 inhibitor, and is highly selective for Cox-1 (IC50 of 0.009 μM) over Cox-2 (IC50 of 6.3 μM). SC 560 also inhibits UTP-stimulated and basal cAMP levels. Cox-1 is shown to catalyze the conversion of Arachidonic Aci Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description Selective cyclooxygenase-1 (COX-1) inhibitor, exhibiting 700-fold selectivity for COX-1 over COX-2.
Names and Identifiers IUPAC Name 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)pyrazole INCHI InChI=1S/C17H12ClF3N2O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3 InChi Key PQUGCKBLVKJMNT-UHFFFAOYSA-N Canonical SMILES COC1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)Cl Isomeric SMILES COC1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)Cl WGK Germany 3 PubChem CID 4306515 Molecular Weight 352.74
Chemical and Physical Properties Sensitivity heat sensitive Boil Point(°C) 440.58° C at 760 mmHg Melt Point(°C) 1.56
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
