Akt activator. Binds to the pleckstrin homology domain. Suppress excitotoxicity-induced neuronal death. Shows neuroprotective effects in vivo . Blood-brain barrier permeable.
Storage Temp
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
1.Niu S et al.. (2018) Beta-Arrestin 1 Mediates Liver Thyrotropin Regulation of Cholesterol Conversion Metabolism via the Akt-Dependent Pathway.. Int J Endocrinol, 2018 (4371396). [PMID:29853881]
2.Nakao M et al.. (2021) Empagliflozin maintains capillarization and improves cardiac function in a murine model of left ventricular pressure overload.. Sci Rep, 11 (18384). [PMID:34526601]
3.Zhao Y et al.. (2021) Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway.. Mol Med Rep, 23 (6):[PMID:33880579]
4.Wang F et al.. (2019) lncRNA CADM1-AS1 inhibits cell-cycle progression and invasion via PTEN/AKT/GSK-3ß axis in hepatocellular carcinoma.. Cancer Manag Res, 11 (3813-3828). [PMID:31118799]
5.Sun Z et al.. (2019) Mucin O-glycosylating enzyme GALNT2 facilitates the malignant character of glioma by activating the EGFR/PI3K/Akt/mTOR axis.. Clin Sci (Lond), 133 (10):(1167-1184). [PMID:31076460]
6.Xu F et al.. (2018) Pectolinarigenin inhibits non-small cell lung cancer progression by regulating the PTEN/PI3K/AKT signaling pathway.. Oncol Rep, 40 (6):(3458-3468). [PMID:30542737]
7.Cao Z et al.. (2021) Silencing of NACC1 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells via regulating the AKT/mTOR signaling pathway.. Oncol Lett, 22 (6):(828). [PMID:34691255]
8.Gamero-Estevez E et al.. (2019) Temporal Effects of Quercetin on Tight Junction Barrier Properties and Claudin Expression and Localization in MDCK II Cells.. Int J Mol Sci, 20 (19):[PMID:31581662]
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L2207563