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SCH-23390 , CAS No.87075-17-0, Antagonist of D 1 receptor;Antagonist of D 5 receptor;Channel blocker of K ir2.3;Gating inhibitor of K ir3.2

Moligand™

CAS#: 87075-17-0
PubChem CID: 5018

Item Number

S613487

Grouped product items
SKU	Size	Availability	Price	Qty
S613487-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$700.90
S613487-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

D1 receptor Antagonist D5 receptor Antagonist Kir2.3 Channel blocker Kir3.2 Gating inhibitor

Basic Description

Synonyms	[3H]-SCH23390\|7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol\|CHEBI:73297\|8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol\|SCH23390\|Sch 23388\|R-(+)-SCH-23390\|[3H]SCH-23390\|GTPL943\|GTPL946\|95191-55-2\|CHEMBL13668\|SCHEMBL572
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST, CHANNEL BLOCKER, GATING INHIBITOR
Mechanism of action	Antagonist of D 1 receptor;Antagonist of D 5 receptor;Channel blocker of K ir2.3;Gating inhibitor of K ir3.2

Associated Targets

DRD1 Tclin D(1A) dopamine receptor 5 Activities

Discover Target: DRD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD2 Tclin D(2) dopamine receptor 0 Activities

Discover Target: DRD2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNJ4 Tchem Inward rectifier potassium channel 4 0 Activities

Discover Target: KCNJ4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNJ6 Tchem G protein-activated inward rectifier potassium channel 2 0 Activities

Discover Target: KCNJ6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DRD5 Tchem D(1B) dopamine receptor 2 Activities

Discover Target: DRD5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities

Discover Target: HTR2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities

Discover Target: HTR1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
INCHI	InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3
InChi Key	GOTMKOSCLKVOGG-UHFFFAOYSA-N
Canonical SMILES	CN1CCc2c(C(C1)c1ccccc1)cc(c(c2)Cl)O
Isomeric SMILES	CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Cl
PubChem CID	5018

PubChem CID

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ChEMBL Ligand

CAS Registry No.

GPCRdb Ligand

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