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Schizandrin B - 10mM in DMSO, high purity , CAS No.61281-37-6

  • 10mM in DMSO
Item Number
S425073
Grouped product items
SKUSizeAvailabilityPrice Qty
S425073-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$171.90

Anti-inflammatory and antioxidant agent

Basic Description

SynonymsSchisandrin B|Schizandrin B|61281-37-6|CHEMBL479488|Schizandrin-B;Wuweizisu-B;gamma-Schisandrin|3,4,5,19-tetramethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaene|S(-) Schisandrin B|Schizandrin-B|1,2,3,13-t
Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsAnti-inflammatory and antioxidant agent. Inhibits ROS production in microglia. Modulates NFκB and Nrf2. Modulates proliferation and phosphorylation of c-Raf, MEK, ERK, JNK, and p38. Shows hepatoprotective and cardioprotective effects in vivo. Orally activ
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Schisandrin B exhibits antioxidant activity which may be responsible for its hepatic protecting activity. It was shown to increase glutathione level and Dt-diaphorase enzyme activity
A compound shown to up-regulate cellular antioxidant response.

Associated Targets

PRKDC Tchem DNA-dependent protein kinase catalytic subunit 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ATR Tchem Serine/threonine-protein kinase ATR 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ATM Tchem Serine-protein kinase ATM 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABCC1 Tchem Multidrug resistance-associated protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 3,4,5,19-tetramethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaene
INCHI InChI=1S/C23H28O6/c1-12-7-14-9-16(24-3)20(25-4)22(26-5)18(14)19-15(8-13(12)2)10-17-21(23(19)27-6)29-11-28-17/h9-10,12-13H,7-8,11H2,1-6H3
InChi Key RTZKSTLPRTWFEV-UHFFFAOYSA-N
Canonical SMILES CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)OC)OC)OCO3
Isomeric SMILES CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)OC)OC)OCO3
PubChem CID 108130
Molecular Weight 400.4648

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