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Scutellarein - ≥98% (HPLC), high purity , CAS No.529-53-3, Agonist of TAS2R39;Channel blocker of TRPM8
Basic Description Synonyms Scutellarein|529-53-3|6-Hydroxyapigenin|5,6,7,4'-Tetrahydroxyflavone|4',5,6,7-tetrahydroxyflavone|5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one|5,6,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one|4',5,6,7-Tetrahydroxyflavanone|SCUTELLARTLN|5,6,7-Tri Specifications & Purity Moligand™, ≥98%(HPLC) Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type AGONIST, CHANNEL BLOCKER Mechanism of action Agonist of TAS2R39;Channel blocker of TRPM8 Product Description Flavonoid that is selectively cytotoxic toward cancer cells. Induces mitochondrial ROS, DNA damage, and metabolic suppression, preferentially in tumor cells. Scutellarein has been shown to have better absorption than scutellarin in Caco-2 monolayer cells.
Names and Identifiers IUPAC Name 5,6,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one INCHI InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H InChi Key JVXZRQGOGOXCEC-UHFFFAOYSA-N Canonical SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O Isomeric SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O PubChem CID 5281697 Molecular Weight 286.24
Chemical and Physical Properties Solubility solubility DMSO: 1 mg/mL, clear, greenish-yellow Sensitivity Light sensitive Melt Point(°C) 347°C
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G2201432