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Scutellarin - analytical standard, high purity , CAS No.27740-01-8

analytical standard

CAS#: 27740-01-8
Formula: C₂₁H₁₈O₁₂
Molecular Weight: 462.37
PubChem CID: 185617

Item Number

S107670

Grouped product items
SKU	Size	Availability	Price	Qty
S107670-20mg	20mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$56.90
S107670-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$169.90

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STAT

Basic Description

Synonyms	Scutellarin\|27740-01-8\|Breviscapin\|Scutellarin B\|Scutellarein-7-glucuronide\|Breviscapine\|Scutellarein-7beta-D-glucuronoside\|Scutellarein-7beta-D-glucuronide\|Scutellarein 7-beta-D-glucuronide\|Scutellarein-7-O-beta-D-glucuronide\|116122-36-2\|(2S,3S,4S,5R,6S)
Specifications & Purity	analytical standard
Biochemical and Physiological Mechanisms	Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion mode
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	analytical standard
Product Description	Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively.

Associated Targets

ESR1 Tclin Estrogen receptor 0 Activities

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SLC22A7 Tbio Solute carrier family 22 member 7 0 Activities

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ABCB1 Tchem Multidrug resistance protein 1 0 Activities

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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

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UGT1A10 Tbio UDP-glucuronosyltransferase 1-10 0 Activities

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UGT1A1 Tchem UDP-glucuronosyltransferase 1-1 0 Activities

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UGT1A8 Tbio UDP-glucuronosyltransferase 1-8 0 Activities

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SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 0 Activities

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PKM Tchem Pyruvate kinase PKM 0 Activities

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MMP1 Tchem Interstitial collagenase 0 Activities

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MMP7 Tchem Matrilysin 0 Activities

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MMP13 Tchem Collagenase 3 0 Activities

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MMP9 Tchem Matrix metalloproteinase-9 0 Activities

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MMP2 Tchem 72 kDa type IV collagenase 0 Activities

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ABCC2 Tchem Canalicular multispecific organic anion transporter 1 0 Activities

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ABCC3 Tbio Canalicular multispecific organic anion transporter 2 0 Activities

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XDH Tclin Xanthine dehydrogenase/oxidase 0 Activities

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ABCG2 Tchem ATP-binding cassette sub-family G member 2 0 Activities

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HTR7 Tclin 5-hydroxytryptamine receptor 7 0 Activities

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

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ABCC1 Tchem Multidrug resistance-associated protein 1 0 Activities

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Names and Identifiers

IUPAC Name	(2S,3S,4S,5R,6S)-6-[5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
INCHI	InChI=1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
InChi Key	DJSISFGPUUYILV-ZFORQUDYSA-N
Canonical SMILES	C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O)O
Isomeric SMILES	C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O)O
PubChem CID	185617
Molecular Weight	462.37

Certificates

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4 results found

Lot Number	Certificate Type	Date	Item
F2418060	Certificate of Analysis	May 25, 2024	S107670
C2313729	Certificate of Analysis	Nov 28, 2022	S107670
C2313766	Certificate of Analysis	Nov 28, 2022	S107670
C1708035	Certificate of Analysis	Aug 08, 2022	S107670

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