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Semilicoisoflavone B - ≥99.0%, high purity , CAS No.129280-33-7
Flavonoids Isoflavones Phenols Polyphenols
Basic Description Synonyms Semilicoisoflavone B|129280-33-7|UNII-T9TP371NFX|T9TP371NFX|CHEBI:69093|5,7-dihydroxy-3-(8-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one|DTXSID60156133|4H-1-BENZOPYRAN-4-ONE, 5,7-DIHYDROXY-3-(8-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-6-YL)-|5,7,8'-Trihydrox Specifications & Purity ≥99.0% Storage Temp Protected from light,Store at -20°C,Desiccated Shipped In Dry ice Product Description Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β ( Aβ ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation.
Form:Solid
Names and Identifiers IUPAC Name 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one INCHI InChI=1S/C20H16O6/c1-20(2)4-3-10-5-11(6-15(23)19(10)26-20)13-9-25-16-8-12(21)7-14(22)17(16)18(13)24/h3-9,21-23H,1-2H3 InChi Key LWZACZCRAUQSLH-UHFFFAOYSA-N Canonical SMILES CC1(C=CC2=C(O1)C(=CC(=C2)C3=COC4=CC(=CC(=C4C3=O)O)O)O)C Isomeric SMILES CC1(C=CC2=C(O1)C(=CC(=C2)C3=COC4=CC(=CC(=C4C3=O)O)O)O)C PubChem CID 5481948 Molecular Weight 352.34
Chemical and Physical Properties Solubility DMSO : 50 mg/mL (141.91 mM; ultrasonic and warming and heat to 60°C) Flash Point(°F) Not applicable Flash Point(°C) Not applicable
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