SENP1-IN-1 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 29. SENP1-IN-1 is developed for tumor radiosensitivity enhancement
In Vitro
SENP1-IN-1 may improve the sensitivity of tumor cells to irradiation. SENP1-IN-1 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC 50 of >20μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Cytotoxicity AssayCell Line: Hela cells Concentration: 0.7 μM, 2.2 μM, 6.6 μM, 20 μM Incubation Time: 72 hours Result: IC 50 >20 μM