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Sigma-LIGAND-1 - 99%, high purity , CAS No.139652-01-0

  • ≥99%
Item Number
S648620
Grouped product items
SKUSizeAvailabilityPrice Qty
S648620-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$510.90
S648620-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$820.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsSigma-LIGAND-1 is a selective sigma receptor ligand with an IC 50 s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a K i of 4000 nM at the dopamine D 2 receptor.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Sigma-LIGAND-1 is a selective sigma receptor ligand with an IC 50 s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a K i of 4000 nM at the dopamine D 2 receptor

In Vivo

Administration of Sigma-LIGAND-1 would reverse amphetamine-induced hyperlocomotion in mice, a behavioral model sensitive to antipsychotic compounds. Sigma-LIGAND-1 and its structural analogues have the potential antipsychotic activity . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 16 nM (DTG site of sigma receptor), 19 nM (PPP site of sigma receptor), Ki: 4000 nM (Dopamine D2 receptor)

Names and Identifiers

Canonical SMILES O=C1C(C)=C(C2=CC=CC=C2)OC3=CC=C(OCCCCCCN4CCC(O)CC4)C=C13
Molecular Weight 435.56

Certificates

C of A & Other Certificates

Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (229.59 mM; Need ultrasonic)

Related Documents

Solution Calculators