| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| S344173-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $599.90 |
a deuterated PDE5 inhibitor
| Synonyms | UK-92480-d8 | 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8) | 7H-Pyrazolo[4,3-d]pyrimidin-7-one |
|---|---|
| Specifications & Purity | ≥98%,≥98atom%D |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Sildenafil-d8 is the deuterium labeled Sildenafil. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM |
| IUPAC Name | 5-[2-ethoxy-5-(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one |
|---|---|
| INCHI | InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)/i10D2,11D2,12D2,13D2 |
| InChi Key | BNRNXUUZRGQAQC-BGKXKQMNSA-N |
| Canonical SMILES | [2H]C1([2H])N(C)C([2H])([2H])C([2H])([2H])N(C1([2H])[2H])S(=O)(=O)c2ccc(OCC)c(c2)C3=Nc4c(CCC)nn(C)c4C(=O)N3 |
| Isomeric SMILES | [2H]C1(C(N(C(C(N1C)([2H])[2H])([2H])[2H])S(=O)(=O)C2=CC(=C(C=C2)OCC)C3=NC4=C(C(=O)N3)N(N=C4CCC)C)([2H])[2H])[2H] |
| Alternate CAS | 139755-83-2（Unlabelled） |
| PubChem CID | 135949536 |
| Molecular Weight | 482.63 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2415513 | Certificate of Analysis | Apr 29, 2024 | S344173 |
| Melt Point(°C) | 188-190° C |
|---|
