Basic Description

Synonyms

Specifications & Purity

Ph.Eur., NF, JP, E 460(i) and Silica, Colloidal Anhydrous, Ph.Eur., E 551

Shipped In

Normal

Grade

JP, NF, Ph.Eur.

Product Description

Silicified Microcrystalline Cellulose, a unique complex of Microcrystalline Cellulose (MCC) and Colloidal Silicon Dioxide (CSD). A highly functional and multifunctional excipient that simplifies the process, and the inherent high functionality imparts effective functionality to the formulation. It has good fluidity, compressibility and dispersion in formulations. At the same time, it has two properties of brittle fracture and plastic deformation, and has better adhesion performance. The distribution of CSD particles in silicified microcrystalline cellulose is uniform, so the specific surface area is five times that of MCC, and the compressibility is improved by 30%-50%. The increase in specific surface area leads to better fluidity and compressibility, thereby improving formulation content uniformity and stability.

When used for direct compression, the granulation process can be omitted, and the types and amounts of auxiliary materials can also be greatly reduced, and excellent, uniform and cost-saving tablets can be prepared.

Product specifications

SKU	Average Particle Size by Laser Diffraction (µm)	Bulk Density (g/mL)	Main Application
S489679-01	65	0.25-0.37	Formulas in which optimal compaction and decent flow is required.
S489679-02	50	0.20-0.30	Best in class binder.
S489679-03	125	0.25-0.37	Formulas in which a balance of flow and compaction is required.
S489679-04	125	0.38-0.50	Formulas in which optimal flow and consolidation is required. This grade shows the best disintegration times. *Low moisture grade available on request.
S489679-05	125	0.27-0.39	Equivalent to quality of SMCC 90, but with lower moisture content (< 3%)

Benefits

1.Excellent compactibility,

2.High intrinsic flow,

3.Enhanced lubrication efficiency,

4.Improved blending properties,

5.Superior binding properties,

6.Increased production capacity.

Names and Identifiers

IUPAC Name	(6S)-2-(hydroxymethyl)-6-[(3S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
INCHI	InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3?,4?,5?,6?,7?,8?,9?,10-,11?,12+/m1/s1
InChi Key	GUBGYTABKSRVRQ-WFVLMXAXSA-N
Isomeric SMILES	C(C1[C@H](C(C(C(O1)O)O)O)O[C@H]2C(C(C(C(O2)CO)O)O)O)O
WGK Germany	3
RTECS	FJ5691460
PubChem CID	16211032

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot Number	Certificate Type	Date	Item
A2424390	Certificate of Analysis	Sep 19, 2023	S489679
A2424392	Certificate of Analysis	Sep 19, 2023	S489679
G23131356	Certificate of Analysis	Jul 04, 2023	S489679

Safety and Hazards(GHS)

WGK Germany	3
RTECS	FJ5691460

Citations of This Product

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46. Fahui Li, Yiyue Shen, Yupei Deng, Jingchun Zhang, Qiqi Wang, Haoyuan Chen, Mai Ouyang, Qianwen Jiang, Guowei Wang, Linghua Zhuang. (2023) Experimental and theoretical studies on dissolution and regeneration of microcrystalline cellulose with dihydroxyl ionic liquids. JOURNAL OF MOLECULAR LIQUIDS, 389 (122928). [PMID:]
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51. Li-Li Sun, Yu Li, Xue-Fei Cao, Shuang-Quan Yao, Shao-Ni Sun. (2023) Insights on structure and antioxidant properties of lignin extracted from Eucalyptus by deep eutectic solvent/2-methyltetrahydrofuran biphasic system treatment. INDUSTRIAL CROPS AND PRODUCTS, 204 (117271). [PMID:]
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54. Duoduo He, Liying Qian, Xingyu Chen, Beihai He, Junrong Li. (2023) Durable cellulose paper by grafting thiol groups and controlling silver deposition for ultrahigh electromagnetic interference shielding. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 248 (125972). [PMID:37499713]
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57. Xiao Li, Yaping Zhu, Siqi Zhang, Xuehui Zhang, Yang Liu, Xiaogang Wu, Yanru Xue, Yi-Xian Qin, Yanqin Wang, Weiyi Chen. (2023) Composite biomaterial for mimetic electric skin generated by conductive polymer/anion synergistic effect. Journal of Materials Chemistry C, 11 (39): (13300-13310). [PMID:]
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60. Lin Yang, Yudong Fu, Honghai Liu, Qiaojun Nie, Ming Zhang, Zhongrong Shen. (2023) Investigating the Zinc Deposition Behavior in Aqueous Zinc-Ion Batteries with PEG/Cellulose/ZnCl2 Water-In-Salt Electrolytes via a Homemade Visualized Three-Electrode Tubular Cell. ACS Sustainable Chemistry & Engineering, 11 (28): (10311–10323). [PMID:]
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67. Jing-Jing Luo, Ming-Shuai Sun, Boyuan Tang, Yan Zhou, Wen-Ting Chen, Wen-Qiang Gong, Song Han, Fei-Feng Mao, Zhang-Min Li, Duan-Jian Tao. (2023) Solvent-Controlled Product Distribution in Vanillin Hydrogenation over a N-Doped Carbon-Supported Nickel Catalyst. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 62 (23): (9134–9143). [PMID:]
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70. Tihang Liu, Jiangang Wang, Hongyou Cui, Jinghua Wang. (2023) Conversion of biomass-derived sugars to 1,1,2-trialkoxyethane via a [2 + 4] retro-aldol reaction over alkaline and alkaline earth metal salts of phosphotungstic acid. GREEN CHEMISTRY, 25 (11): (4565-4576). [PMID:]
71. Lin Zhang, Jili Yuan, Qinqin Xu, Fazhi Zhang, Qi Sun, Haibo Xie. (2023) Noble-metal-free Co-N-C catalyst derived from cellulose-based poly(ionic liquid)s for highly efficient oxygen reduction reaction. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 242 (125110). [PMID:37257539]
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73. Miao Wang, Shuai Zhang, Xiangjun Liu, Yayun Ma, Junqi Wang. (2023) Catalytic co-pyrolysis of cellulose over alkali and alkaline earth metal salts for levoglucosan production. INDUSTRIAL CROPS AND PRODUCTS, 201 (116925). [PMID:]
74. Pu Huang, Xinzheng Wei, Xinmei Wang, Zhengjun Gu, Yafei Guo, Chuanwen Zhao. (2023) Facile fabrication of silica aerogel supported amine adsorbent pellets for Low-concentration CO2 removal from confined spaces. CHEMICAL ENGINEERING JOURNAL, 468 (143629). [PMID:]
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64. Shoucun Zhang, Yujing Bian, Xueyin Yan, Guoli Fang, Shengwei Guo. (2023) Preparation of CO2 responsive cellulose composite adsorbent and its application in protein separation. JOURNAL OF APPLIED POLYMER SCIENCE, 140 (33): (e54268). [PMID:]
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66. Srinivasan Vinju Vasudevan, Jin Cai, Junming Xu, Hongjian Lin, Hongliang Wang, Quan Bu. (2023) Microwave-Assisted Catalytic Conversion of 5-HMF for Biofuel Additives by Molybdophosphoric Acid Encapsulated KCC-1. Catalysts, 13 (6): (969). [PMID:]
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70. Tihang Liu, Jiangang Wang, Hongyou Cui, Jinghua Wang. (2023) Conversion of biomass-derived sugars to 1,1,2-trialkoxyethane via a [2 + 4] retro-aldol reaction over alkaline and alkaline earth metal salts of phosphotungstic acid. GREEN CHEMISTRY, 25 (11): (4565-4576). [PMID:]
71. Lin Zhang, Jili Yuan, Qinqin Xu, Fazhi Zhang, Qi Sun, Haibo Xie. (2023) Noble-metal-free Co-N-C catalyst derived from cellulose-based poly(ionic liquid)s for highly efficient oxygen reduction reaction. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 242 (125110). [PMID:37257539]
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73. Miao Wang, Shuai Zhang, Xiangjun Liu, Yayun Ma, Junqi Wang. (2023) Catalytic co-pyrolysis of cellulose over alkali and alkaline earth metal salts for levoglucosan production. INDUSTRIAL CROPS AND PRODUCTS, 201 (116925). [PMID:]
74. Pu Huang, Xinzheng Wei, Xinmei Wang, Zhengjun Gu, Yafei Guo, Chuanwen Zhao. (2023) Facile fabrication of silica aerogel supported amine adsorbent pellets for Low-concentration CO2 removal from confined spaces. CHEMICAL ENGINEERING JOURNAL, 468 (143629). [PMID:]
75. Siyu Li, Weijun Shan, Ting Rao, Yanou Qi, Ying Xiong, Zhenning Lou, Haibiao Yu, Junshuo Cui, Xiaogeng Feng. (2023) Facile synthesis of a novel CAU-17/CSG composite for the trace electrochemical analysis of Zn2+, Cd2+ and Pb2+. MICROCHEMICAL JOURNAL, 191 (108861). [PMID:]
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82. Guozhi Fan, Yi Chen, Yuchan Lu, Qunpeng Cheng, Bo Chai, Guangsen Song. (2023) Co-production of 5-hydroxymethyl furfural and furfural from holocellulose over UiO-66-derived acid-base catalysts. CHEMICAL ENGINEERING SCIENCE, 276 (118768). [PMID:]
83. Kaifeng Lu, Yifan Wang, Lingjun Zhu, Bo Xing, Shurong Wang. (2023) Efficient Conversion of Biomass-Derived Saccharides to Levulinic Acid Using Silicotungstic Acid. ENERGY & FUELS, 37 (9): (6642–6650). [PMID:]
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86. Shangzhong Zhang, Yi Duan, Changchang Teng, Hongdong Quan, Xiuguo Yang, Hongyan Li, Xiaohe Li, Lifeng Yan. (2023) Fast and Selective Degradation of Biomass for Xylose, Glucose and Lignin under Mild Conditions. MOLECULES, 28 (8): (3306). [PMID:37110540]
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94. Yinan Li, Jun Wang, Jiajia Guo, Chenglong Fu, Liulian Huang, Lihui Chen, Yonghao Ni, Qinghong Zheng. (2023) UV and IR dual light triggered cellulose-based invisible actuators with high sensitivity. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 238 (124031). [PMID:36933599]
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108. Longfei Xie, Le Gou, Donghai Xu, Krzysztof Kapusta, Liyi Dai, Yuanyuan Wang. (2023) Coupling influences of organic components and temperature on nitrogen transformation and hydrochar characterization during hydrothermal carbonization of sewage sludge. SCIENCE OF THE TOTAL ENVIRONMENT, 866 (161354). [PMID:36603624]
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135. Haoran Yuan, Chengyu Li, Rui Shan, Jun Zhang, Lingjun Zhu, Yong Chen. (2022) Municipal sludge derived solid acids for levoglucosenone production via cellulose fast pyrolysis. JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS, 167 (105663). [PMID:]
136. Gang Wu, Haojie Yang, Wenran Gao, Kui Wang, Maxim V. Penzik, Alexander N. Kozlov, Bin Li, Yong Huang, Shu Zhang, Hong Zhang. (2022) The importance of cobalt disulfide morphology for cellulose depolymerization: Hydrogenolysis versus acid catalysis. JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS, 167 (105659). [PMID:]
137. Qiaozhi Ma, Jianying Lin, Mingzhao Guan, Haotong Liang, Qiyu Liu. (2022) Enhanced cello-oligosaccharides production from cellulose hydrolysis in molten salt hydrate over lignin-based hyper-cross-linked polymer (LHCP) adsorption. APPLIED CATALYSIS A-GENERAL, 644 (118808). [PMID:]
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140. Qiuyan Zhang, Xiaohui Liu, Yuanlin Ren, Yuesheng Li. (2022) Phosphorated cellulose as a cellulose-based filler for developing continuous fire resistant lyocell fibers. Journal of Cleaner Production, 368 (133242). [PMID:]
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Silicified Microcrystalline Cellulose - Ph.Eur., NF, JP, E 460(i) and Silica, Colloidal Anhydrous, Ph.Eur., E 551, high purity , CAS No.9004-34-6