Simvastatin Ammonium Salt - 95%, high purity , CAS No.139893-43-9

Item Number

S302812

Grouped product items
SKU	Size	Availability	Price
S302812-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$15.90
S302812-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$45.90
S302812-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$189.90
S302812-25g	25g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$649.90

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Basic Description

Synonyms	Simvastatin acid (ammonium) \| Tenivastatin ammonium salt \| Simvastatin ammonium salt \| 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-, ammonium salt (1:1), (betaR,deltaR,1S,2S,6R,8S,8aR)
Specifications & Purity	95%
Storage Temp	Store at -20°C,Argon charged,Desiccated
Shipped In	Ice chest + Ice pads
Product Description	Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

Names and Identifiers

IUPAC Name	(3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid;azane
INCHI	InChI=1S/C25H40O6.H3N/c1-6-25(4,5)24(30)31-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-18(26)13-19(27)14-22(28)29;/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29);1H3/t15-,16-,18+,19+,20-,21-,23-;/m0./s1
InChi Key	FFPDWNBTEIXJJF-OKDJMAGBSA-N
Canonical SMILES	CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)C.N
Isomeric SMILES	CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)C.N
PubChem CID	12967766
Molecular Weight	453.61

Certificates

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8 results found

Lot Number	Certificate Type	Date	Item
E2431539	Certificate of Analysis	Jan 30, 2024	S302812
E2431548	Certificate of Analysis	Jan 30, 2024	S302812
E2431554	Certificate of Analysis	Jan 30, 2024	S302812
E2431558	Certificate of Analysis	Jan 30, 2024	S302812
E2431579	Certificate of Analysis	Jan 30, 2024	S302812
E2431599	Certificate of Analysis	Jan 30, 2024	S302812
E2431600	Certificate of Analysis	Jan 30, 2024	S302812
E2431601	Certificate of Analysis	Jan 30, 2024	S302812

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H351:Suspected of causing cancer H412:Harmful to aquatic life with long lasting effects H318:Causes serious eye damage H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.

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Basic Description