| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| S655046-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $55.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | SIRT-IN-3 is a potent SIRT inhibitor, with an IC 50 of 17 μM for SIRT1. SIRT-IN-3 shows about 4-fold and 14-fold selectivity for SIRT1 over SIRT2 and SIRT3 , respectively (IC 50 of 74 μM and 235 μM for SIRT2 and SIRT3 , respectively). In Vitro SIRT-IN-3 (Compound 7) (30-300 μM; 8 hours) causes p53 acetylation in in HCT116 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Canonical SMILES | C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)N |
|---|---|
| Molecular Weight | 212.25 |
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