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SJFα - 99%, high purity , CAS No.2254609-27-1

≥99%

CAS#: 2254609-27-1
Formula: C₅₉H₆₇F₂N₇O₁₁S
Molecular Weight: 1120.27

Item Number

S648388

Grouped product items
SKU	Size	Availability	Price
S648388-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$490.90
S648388-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,020.90
S648388-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$260.90

View related series

MAPK/ERK Pathway p38 MAPK PROTAC PROTACs

Basic Description

Specifications & Purity	99%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	SJFα is a 13-atom linker PROTAC based on von Hippel-Lindau ligand. SJFα degrades p38α with a DC 50 of 7.16 nM, but is far less effective at degrading p38δ (DC 50 =299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 µM Form:Solid IC50& Target:p38α 7.16 nM (DC 50 ) p38δ 299 nM (DC 50 ) VHL

Canonical SMILES

FC1=CC=C(NC(C2(CC2)C(NC3=CC(F)=C(OC4=C(C=C(OC)C(OCCCCOCCCCOCC(N[C@@H](C(C)(C)C)C(N5[C@H](C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)C[C@@H](O)C5)=O)=O)=C8)C8=NC=C4)C=C3)=O)=O)C=C1

Molecular Weight

1120.27

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SJFα - 99%, high purity , CAS No.2254609-27-1

Basic Description

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

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