Name: Sodium bis(trimethylsilyl)amide solution - 0.5 M in methyl tert-butyl ether, high purity , CAS No.1070-89-9
Price: 180.9 USD
Availability: InStock

Basic Description

Synonyms	Sodium bis(trimethylsilyl)amide\|1070-89-9\|NaHMDS\|N-Sodiohexamethyldisilazane\|Sodium Hexamethyldisilazide\|Hexamethyldisilazane sodium salt\|sodium;bis(trimethylsilyl)azanide\|MFCD00009835\|Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, sodium salt\|sodium he
Specifications & Purity	0.5 M in methyl tert-butyl ether
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	Application Strong base for kinetically controlled deprotonations.

Names and Identifiers

IUPAC Name	sodium;bis(trimethylsilyl)azanide
INCHI	InChI=1S/C6H18NSi2.Na/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
InChi Key	WRIKHQLVHPKCJU-UHFFFAOYSA-N
Canonical SMILES	C[Si](C)(C)[N-][Si](C)(C)C.[Na+]
Isomeric SMILES	C[Si](C)(C)[N-][Si](C)(C)C.[Na+]
WGK Germany	3
PubChem CID	2724254
UN Number	3263
Packing Group	II
Molecular Weight	183.37
Beilstein	3629917
Reaxy-Rn	3629917

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Flash Point(°F)	1 °F
Flash Point(°C)	-17 °C
Melt Point(°C)	171-175°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05
Signal	Danger
Hazard Statements	H314:Causes severe skin burns and eye damage H412:Harmful to aquatic life with long lasting effects H302+H312+H332:Harmful if swallowed, in contact with skin or if inhaled
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P362+P364:Take off contaminated clothing and wash it before reuse. P301+P312+P330:IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.
WGK Germany	3
Reaxy-Rn	3629917
Class	8（3）

References

1. Hua Lu,Jianjun Cheng. (2007-10-30) Hexamethyldisilazane-mediated controlled polymerization of alpha-amino acid N-carboxyanhydrides.. Journal of the American Chemical Society, 129 ((46)): (14114-14115). [PMID:17963385]
2. H B Lazrek,D Ouzebla,L Baddi,J J Vasseur. (2007-12-07) Glycosylation reaction via a mild and efficient one-pot reaction using doped natural phosphate with iodine as catalyst.. Nucleosides, nucleotides & nucleic acids, 26 ((8-9)): (1095-1098). [PMID:18058543]
3. Tong Zhang,Ibrahim Khadra,Melvin R Euerby,Graham G Skellern,David G Watson,Justice N A Tettey. (2008-01-24) Simultaneous analysis of basic, acidic and neutral compounds on an endcapped octadecylsilane silica-based monolith by pressure-assisted capillary electrochromatography.. Electrophoresis, 29 ((4)): (944-951). [PMID:18213596]
4. Daniele Fabbri,Leszek Marynowski,Monika J Fabiańska,Michał Zatoń,Bernd R T Simoneit. (2008-05-24) Levoglucosan and other cellulose markers in pyrolysates of Miocene lignites: geochemical and environmental implications.. Environmental science & technology, 42 ((8)): (2957-2963). [PMID:18497150]
5. Takashi Nagase,Yoshihiro Sasazaki,Toshiyuki Kikuchi,Masafumi Machida. (2008-10-03) Rapid 3-dimensional imaging of embryonic craniofacial morphology using microscopic computed tomography.. Journal of computer assisted tomography, 32 ((5)): (816-821). [PMID:18830118]
6. A Sebok,K Sezer,A Vasanits-Zsigrai,A Helenkár,Gy Záray,I Molnár-Perl. (2008-10-14) Gas chromatography-mass spectrometry of the trimethylsilyl (oxime) ether/ester derivatives of cholic acids: their presence in the aquatic environment.. Journal of chromatography. A, 1211 ((1-2)): (104-112). [PMID:18849033]
7. Nan Li,Chih-Ming Ho. (2008-11-22) Photolithographic patterning of organosilane monolayer for generating large area two-dimensional B lymphocyte arrays.. Lab on a chip, 8 ((12)): (2105-2112). [PMID:19023473]
8. Werner Mormann,Markus Wezstein. (2008-11-26) Trimethylsilylation of cellulose in ionic liquids.. Macromolecular bioscience, 9 ((4)): (369-375). [PMID:19031387]
9. Jerry Isaacson,Yoshihisa Kobayashi. (2009-01-29) An Ugi reaction in the total synthesis of (-)-dysibetaine.. Angewandte Chemie (International ed. in English), 48 ((10)): (1845-1848). [PMID:19173271]
10. Elsa Vennat,Christine Bogicevic,Jean-Marie Fleureau,Michel Degrange. (2009-01-29) Demineralized dentin 3D porosity and pore size distribution using mercury porosimetry.. Dental materials : official publication of the Academy of Dental Materials, 25 ((6)): (729-735). [PMID:19174308]
11. Hung-Che Chou,Tsong-Rong Yan,Ko-Shao Chen. (2009-06-24) Detecting cells on the surface of a silver electrode quartz crystal microbalance using plasma treatment and graft polymerization.. Colloids and surfaces. B, Biointerfaces, 73 ((2)): (244-249). [PMID:19545984]
12. Guanxia Shen,Yiqing Lu,Li Shen,Yi Zhang,Shouwu Guo. (2009-07-16) Nondestructively creating nanojunctions by combined-dynamic-mode dip-pen nanolithography.. Chemphyschem : a European journal of chemical physics and physical chemistry, 10 ((13)): (2226-2229). [PMID:19603447]
13. Tatsuya Nitabaru,Akihiro Nojiri,Makoto Kobayashi,Naoya Kumagai,Masakatsu Shibasaki. (2009-09-10) anti-Selective catalytic asymmetric nitroaldol reaction via a heterobimetallic heterogeneous catalyst.. Journal of the American Chemical Society, 131 ((38)): (13860-13869). [PMID:19736990]
14. Haoyu Tang,Donghui Zhang. (2010-05-15) General route toward side-chain-functionalized alpha-helical polypeptides.. Biomacromolecules, 11 ((6)): (1585-1592). [PMID:20465286]
15. D B Mahadik,A Venkateswara Rao,A Parvathy Rao,P B Wagh,S V Ingale,Satish C Gupta. (2011-02-01) Effect of concentration of trimethylchlorosilane (TMCS) and hexamethyldisilazane (HMDZ) silylating agents on surface free energy of silica aerogels.. Journal of colloid and interface science, 356 ((1)): (298-302). [PMID:21277584]
16. Xiaoguang Li,Jun Shen. (2011-08-30) A facile two-step dipping process based on two silica systems for a superhydrophobic surface.. Chemical communications (Cambridge, England), 47 ((38)): (10761-10763). [PMID:21874180]
17. Adrienne C Greene,Cody M Washburn,George D Bachand,Conrad D James. (2011-09-03) Combined chemical and topographical guidance cues for directing cytoarchitectural polarization in primary neurons.. Biomaterials, 32 ((34)): (8860-8869). [PMID:21885117]
18. Zhengtao Deng,Dongran Han,Yan Liu. (2011-09-15) Colloidal synthesis of metastable zinc-blende IV-VI SnS nanocrystals with tunable sizes.. Nanoscale, 3 ((10)): (4346-4351). [PMID:21915425]
19. S V Buravkov,V P Chernikov,L B Buravkova. (2012-03-28) Simple method of specimen preparation for scanning electron microscopy.. Bulletin of experimental biology and medicine, 151 ((3)): (378-382). [PMID:22451892]
20. Juliana Tsz Yan Lee,King Lau Chow. (2012-04-26) SEM sample preparation for cells on 3D scaffolds by freeze-drying and HMDS.. Scanning, 34 ((1)): (12-25). [PMID:22532079]
21. Nur Hazlin Hazrin-Chong,Mike Manefield. (2012-05-09) An alternative SEM drying method using hexamethyldisilazane (HMDS) for microbial cell attachment studies on sub-bituminous coal.. Journal of microbiological methods, 90 ((2)): (96-99). [PMID:22561094]
22. Marko Marinkovic,Dagmawi Belaineh,Veit Wagner,Dietmar Knipp. (2012-06-26) On the origin of contact resistances of organic thin film transistors.. Advanced materials (Deerfield Beach, Fla.), 24 ((29)): (4005-4009). [PMID:22730030]
23. Mario Janjetovic,Annika M Träff,Tobias Ankner,Jenny Wettergren,Göran Hilmersson. (2013-01-30) Solvent dependent reductive defluorination of aliphatic C-F bonds employing Sm(HMDS)2.. Chemical communications (Cambridge, England), 49 ((18)): (1826-1828). [PMID:23358653]
24. Tejia Zhang, Lauren Barclay, Loren D Walensky, Alan Saghatelian,. (2015-06-11) Regulation of mitochondrial ceramide distribution by members of the BCL-2 family.. Journal of lipid research, 56 ((8)): ( 1501-1510 ). [PMID:26059977]
25. Markus Jonek,Janina Diekmann,Christian Ganter. (2015-09-24) First N-Heterocyclic Carbenes Relying on the Triazolone Structural Motif: Syntheses, Modifications and Reactivity.. Chemistry (Weinheim an der Bergstrasse, Germany), 21 ((44)): (15759-15768). [PMID:26395132]

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Sodium bis(trimethylsilyl)amide solution - 0.5 M in methyl tert-butyl ether, high purity , CAS No.1070-89-9