Grouped product items

SKU

Size

Availability

Price

Qty

S104205-5g

Available within 4-8 weeks(?)

$19.90

S104205-25g

25g

Available within 4-8 weeks(?)

$51.90

S104205-100g

100g

Available within 8-12 weeks(?)

$147.90

Basic Description

Synonyms	Sodium cholate hydrate\|206986-87-0\|Sodium cholate hydrate(1:1:1)\|73163-53-8\|sodium;(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;
Specifications & Purity	≥98%
Storage Temp	Argon charged
Shipped In	Normal

Associated Targets

GMNN Tbio Geminin 0 Activities

Discover Target: GMNN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLI Tchem DNA polymerase iota 0 Activities

Discover Target: POLI

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	sodium;(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;hydrate
INCHI	InChI=1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
InChi Key	MUVVIYFKOVLQHL-RCVKHMDESA-M
Canonical SMILES	O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
Isomeric SMILES	C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C.O.[Na+]
WGK Germany	3
PubChem CID	23679061
Molecular Weight	430.55 (anhydrous basis)
Beilstein	3582354

Certificates

Certificate of Analysis(COA)

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9 results found

Lot Number	Certificate Type	Date	Item
D2425371	Certificate of Analysis	May 10, 2024	S104205
D2425493	Certificate of Analysis	May 10, 2024	S104205
D2425494	Certificate of Analysis	May 10, 2024	S104205
L2308020	Certificate of Analysis	Dec 13, 2023	S104205
I2307051	Certificate of Analysis	Sep 13, 2023	S104205
I22081007	Certificate of Analysis	Sep 15, 2022	S104205
I22081008	Certificate of Analysis	Sep 15, 2022	S104205
I2208996	Certificate of Analysis	Sep 15, 2022	S104205
F2222492	Certificate of Analysis	Jun 30, 2022	S104205

Chemical and Physical Properties

Sensitivity	Moisture sensitive.

Safety and Hazards(GHS)

WGK Germany	3

References

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3. Haihong Kang,Mengfei Yan,Qinghua Yu,Qian Yang. (2014-01-07) Characteristics of nasal-associated lymphoid tissue (NALT) and nasal absorption capacity in chicken.. PloS one, 8 ((12)): (e84097-e84097). [PMID:24391892]
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5. Yuri Kashima,Satoshi Kanematsu,Saori Asai,Mio Kusada,Suzuyo Watanabe,Takuji Kawashima,Tadashi Nakamura,Masaya Shimada,Tsuyoshi Goto,Satoshi Nagaoka. (2014-08-22) Identification of a novel hypocholesterolemic protein, major royal jelly protein 1, derived from royal jelly.. PloS one, 9 ((8)): (e105073-e105073). [PMID:25144734]
6. Paola Mura,Marco Bragagni,Natascia Mennini,Marzia Cirri,Francesca Maestrelli. (2014-09-10) Development of liposomal and microemulsion formulations for transdermal delivery of clonazepam: effect of randomly methylated β-cyclodextrin.. International journal of pharmaceutics, 475 ((1-2)): (306-314). [PMID:25194352]
7. Jilite Wang,Masaya Shimada,Yukina Kato,Mio Kusada,Satoshi Nagaoka. (2014-11-07) Cholesterol-lowering effect of rice bran protein containing bile acid-binding proteins.. Bioscience, biotechnology, and biochemistry, 79 ((3)): (456-461). [PMID:25374002]
8. Joelle M Onorato,Ching-Hsuen Chu,Zhengping Ma,Lisa M Kopcho,Hannguang J Chao,R Michael Lawrence,Dong Cheng. (2015-01-20) Cell-based assay of MGAT2-driven diacylglycerol synthesis for profiling inhibitors: use of a stable isotope-labeled substrate and high-resolution LC/MS.. Journal of lipid research, 56 ((3)): (747-753). [PMID:25598079]
9. Eun-Young Lee,So-Hee Kim,Kyung-Hyun Cho. (2015-01-28) Reconstituted High-Density Lipoprotein Containing Human Growth Hormone-1 Shows Potent Tissue Regeneration Activity with Enhancement of Anti-Oxidant and Anti-Atherosclerotic Activities.. Rejuvenation research, 18 ((3)): (245-256). [PMID:25626070]
10. Mayu Kakehi,Yoshinori Ikenaka,Shouta M M Nakayama,Yusuke K Kawai,Kensuke P Watanabe,Hazuki Mizukawa,Kei Nomiyama,Shinsuke Tanabe,Mayumi Ishizuka. (2015-07-17) Uridine Diphosphate-Glucuronosyltransferase (UGT) Xenobiotic Metabolizing Activity and Genetic Evolution in Pinniped Species.. Toxicological sciences : an official journal of the Society of Toxicology, 147 ((2)): (360-369). [PMID:26179383]
11. J Abraham Domínguez-Avila,Humberto Astiazaran-Garcia,Abraham Wall-Medrano,Laura A de la Rosa,Emilio Alvarez-Parrilla,Gustavo A González-Aguilar. (2018-09-07) Mango phenolics increase the serum apolipoprotein A1/B ratio in rats fed high cholesterol and sodium cholate diets.. Journal of the science of food and agriculture, 99 ((4)): (1604-1612). [PMID:30187493]
12. Charlotte Bayer Christiansen,Samuel Addison Jack Trammell,Nicolai Jacob Wewer Albrechtsen,Kristina Schoonjans,Reidar Albrechtsen,Matthew Paul Gillum,Rune Ehrenreich Kuhre,Jens Juul Holst. (2019-02-16) Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents.. American journal of physiology. Gastrointestinal and liver physiology, 316 ((5)): (G574-G584). [PMID:30767682]
13. Jun Xu,Yunfei Hu,Jonas Kaindl,Philipp Risel,Harald Hübner,Shoji Maeda,Xiaogang Niu,Hongwei Li,Peter Gmeiner,Changwen Jin,Brian K Kobilka. (2019-05-20) Conformational Complexity and Dynamics in a Muscarinic Receptor Revealed by NMR Spectroscopy.. Molecular cell, 75 ((1)): (53-65). [PMID:31103421]
14. Liangping Zhao,Li Wang,Daimin Zhang,Yuqi Chen,Fulu Jin. (2020-12-18) Puerarin alleviates coronary heart disease via suppressing inflammation in a rat model.. Gene, 771 (145354-145354). [PMID:33333215]
15. Jacqueline Langedijk,Ruth Bolier,Dagmar Tolenaars,Lysbeth Ten Bloemendaal,Suzanne Duijst,Dirk de Waart,Ulrich Beuers,Piter Bosma,Ronald Oude Elferink. (2021-03-19) Reduced spontaneous itch in mouse models of cholestasis.. Scientific reports, 11 ((1)): (6127-6127). [PMID:33731871]
16. Kyung-Hyun Cho. (2021-07-25) Structural and Functional Impairments of Reconstituted High-Density Lipoprotein by Incorporation of Recombinant β-Amyloid42.. Molecules (Basel, Switzerland), 26 ((14)): [PMID:34299592]
17. Wookju Jang,Nam Ho Jeoung,Kyung-Hyun Cho. (2011-05-03) Modified apolipoprotein (apo) A-I by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state.. Molecules and cells, 31 ((5)): (461-470). [PMID:21533907]
18. Ricarda A Busse,Andreea Scacioc,Javier M Hernandez,Roswitha Krick,Milena Stephan,Andreas Janshoff,Michael Thumm,Karin Kühnel. (2013-03-01) Qualitative and quantitative characterization of protein-phosphoinositide interactions with liposome-based methods.. Autophagy, 9 ((5)): (770-777). [PMID:23445924]
19. Li Lei,Martin Egli. (2016-04-03) In Situ Proteolysis for Crystallization of Membrane Bound Cytochrome P450 17A1 and 17A2 Proteins from Zebrafish.. Current protocols in protein science, 84 (29-29). [PMID:27038268]
20. Ching-Wei Lin,Sergei M Bachilo,Yu Zheng,Uyanga Tsedev,Shengnan Huang,R Bruce Weisman,Angela M Belcher. (2019-06-30) Creating fluorescent quantum defects in carbon nanotubes using hypochlorite and light.. Nature communications, 10 ((1)): (2874-2874). [PMID:31253811]
21. Gomori, et al.. (2021) Cardioprotective Effect of Novel Matrix Metalloproteinase Inhibitors.. International Journal of Molecular Sciences, 21 [PMID:32977437]
22. Ewelina Waglewska,Agata Pucek-Kaczmarek,Urszula Bazylińska. (2020-12-17) Novel Surface-Modified Bilosomes as Functional and Biocompatible Nanocarriers of Hybrid Compounds.. Nanomaterials (Basel, Switzerland), 10 ((12)): [PMID:33321762]

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Sodium cholate hydrate - 98%, high purity , CAS No.206986-87-0