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Sodium diethyldithiocarbamate trihydrate - ACS reagent, high purity , CAS No.20624-25-3

19 Citations

ACS

CAS#: 20624-25-3
Formula: C₅H₁₀NNaS₂·3H₂O
Molecular Weight: 225.31
Beilstein Registry Number: 3920507
EC Number: 205-710-6
MDL number: MFCD00150617
PubChem CID: 517546

Item Number

S104927

Grouped product items
SKU	Size	Availability	Price
S104927-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$28.90
S104927-100g	100g	In stock	$79.90
S104927-500g	500g	In stock	$257.90

Superoxide dismutase (SOD) and NF-κB inhibitor

Basic Description

Synonyms	Sodium diethyldithiocarbamate trihydrate \| EN300-21379 \| Sodium diethyldithiocarbamate trihydrate, JIS special grade, >=92.0% \| Sodium diethyldithiocarbamate trihydrate, Vetec(TM) reagent grade \| SB79573 \| Diethyldithiocarbamic acid sodium salt trihydrate
Specifications & Purity	ACS
Biochemical and Physiological Mechanisms	Inhibits induction of macrophage nitric oxide synthase.Superoxide dismutase (SOD) and NF-κB inhibitor. Nitric oxide (NO) spin-trapping reagent when complexed with Fe 2+ . Active in vivo and in vitro .
Storage Temp	Argon charged
Shipped In	Normal
Grade	ACS
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Names and Identifiers

IUPAC Name	sodium;N,N-diethylcarbamodithioate;trihydrate
INCHI	InChI=1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1
InChi Key	WWGXHTXOZKVJDN-UHFFFAOYSA-M
Canonical SMILES	CCN(CC)C(=S)[S-].O.O.O.[Na+]
Isomeric SMILES	CCN(CC)C(=S)[S-].O.O.O.[Na+]
WGK Germany	3
RTECS	EZ6550000
Alternate CAS	148-18-5
PubChem CID	517546
Molecular Weight	225.31
Beilstein	3920507

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
D23141906	Certificate of Analysis	Jun 26, 2023	S104927
F2310730	Certificate of Analysis	Jun 26, 2023	S104927
F2310728	Certificate of Analysis	Jun 25, 2023	S104927
F2310729	Certificate of Analysis	Jun 25, 2023	S104927
K2217254	Certificate of Analysis	Nov 21, 2022	S104927
E1823148	Certificate of Analysis	Apr 11, 2022	S104927
J2218348	Certificate of Analysis	Nov 22, 2021	S104927

Chemical and Physical Properties

Solubility	Soluble in water, ethanol, methanol and acetone. Insoluble in ether.
Sensitivity	Hygroscopic
Melt Point(°C)	94-98.5°C

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H302:Harmful if swallowed H318:Causes serious eye damage H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	3
RTECS	EZ6550000

Citations of This Product

1. Xueqin Guo,Man He,Beibei Chen,Bin Hu. (2012-05-23) Solidified floating organic drop microextraction combined with ETV-ICP-MS for the determination of trace heavy metals in environmental water samples.. Talanta, 94 (70-76). [PMID:22608416]
2. Jingfang Hu, Linzhe Wang, Yu Song, Yansheng Li, Yu Shen, Guowei Gao, Lei Qin, Jianfeng Wu, Ashok Mulchandani. (2024) Ion imprinted polymers integrated into a multi-functional microfluidic paper-based analytical device for trace cadmium detection in water. Analytical Methods, 16 (2): (179-188). [PMID:38047435]
3. Sujuan Li, Haoqi Wu, Yuhang Sang, Bingtao Wang. (2019) Photoelectrochemical Non-Enzymatic Detection of Glucose at Graphene Supported CdS Nanowires via Decoration of CuO Nanoparticles under visible light. International Journal of Electrochemical Science, 14 (10458). [PMID:]
4. Yuanyuan Jin, Jiabin Zhang, Yanteng Xu, Ke Yi, Fenfang Li, Huicong Zhou, Haixia Wang, Hon Fai Chan, Yeh-Hsing Lao, Shixian Lv, Yu Tao, Mingqiang Li. (2023) Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure. Bioactive Materials, 28 (112). [PMID:37250866]
5. Ziyun Zhong, Hao Fu, Siyuan Wang, Yingnan Duan, Qinglun Wang, Chun-Hua Yan, Yaping Du. (2023) A Universal Synthesis Strategy for Lanthanide Sulfide Nanocrystals with Efficient Photocatalytic Hydrogen Production. Small, 19 (33): (2301392). [PMID:37086136]
6. Chen Xiao, Jiayuan Li, Xing Wang, Shiyou Li, Chen Xu, Zhijie Zhang, Ao Hua, Ze-yang Ding, Bi-xiang Zhang, Xiangliang Yang, Zifu Li. (2023) Hydroxyethyl starch stabilized copper-diethyldithiocarbamate nanocrystals for cancer therapy. JOURNAL OF CONTROLLED RELEASE, 356 (288). [PMID:36870542]
7. Wentao Dang, Yuqin Wang, Wei-Chih Chen, Enguo Ju, Rachel L. Mintz, Yue Teng, Lili Zhu, Kun Wang, Shixian Lv, Hon Fai Chan, Yu Tao, Mingqiang Li. (2023) Implantable 3D Printed Hydrogel Scaffolds Loading Copper-Doxorubicin Complexes for Postoperative Chemo/Chemodynamic Therapy. ACS Applied Materials & Interfaces, 15 (4): (4911–4923). [PMID:36656977]
8. Wendong Xing, Zhongfei Ma, Chong Wang, Jia Gao, Chao Yu, Yongsheng Yan, Li Yan, Chunxiang Li, Yilin Wu. (2023) Hierarchically porous molecularly imprinted membranes with multiple transfer channels for micropollutants selective separation. DESALINATION, 547 (116226). [PMID:]
9. Yafei Zhen, Tao Lin, Hanjiao Chen, Jing Hu, Xiandeng Hou. (2022) Vapor Generation of Rare-Earth Elements via Reaction with Tetrahydroborate: Chemical Identities and Mechanisms of Formation. ANALYTICAL CHEMISTRY, 94 (44): (15176–15182). [PMID:36301518]
10. Wenhao Li, De-Kun Ma, Xia Hu, Faliang Gou, Xiaogang Yang, Walker MacSwain, ChenZe Qi, Weiwei Zheng. (2022) General strategy for enhanced CH4 selectivity in photocatalytic CO2 reduction reactions by surface oxophilicity engineering. JOURNAL OF CATALYSIS, 415 (77). [PMID:]
11. Yao Lu, Qingqing Pan, Wenxia Gao, Yuji Pu, Bin He. (2022) Reversal of cisplatin chemotherapy resistance by glutathione-resistant copper-based nanomedicine via cuproptosis. Journal of Materials Chemistry B, 10 (33): (6296-6306). [PMID:35904024]
12. Kexin Bian, Weitao Yang, Yan Xu, Weiwei Zeng, Hui Wang, Hongying Liang, Tianming Cui, Zhuo Wang, Bingbo Zhang. (2022) Specific-Tuning Band Structure in Hetero-Semiconductor Nanorods to Match with Reduction of Oxygen Molecules for Low-Intensity Yet Highly Effective Sonodynamic/Hole Therapy of Tumors. Small, 18 (31): (2202921). [PMID:35801484]
13. Yali Liu, Wanchun Xiang, Shaiqiang Mou, Hao Zhang, Shengzhong Liu. (2022) Synergetic surface defect passivation towards efficient and stable inorganic perovskite solar cells. CHEMICAL ENGINEERING JOURNAL, 447 (137515). [PMID:]
14. Juxin Yin, Jianjian Zhuang, Xin Zhang, Chaojian Xu, Shaowu Lv. (2022) Ginseng of different ages is affected by the accumulation of heavy metals in ginseng soil. PLoS One, 17 (6): (e0269238). [PMID:35696360]
15. Huizhen Xiao, Guifang Wang, Guangchuan Liang, Jinliang Zhu, Jun Qiu, Chenhui Ding, Sridhar Komarneni. (2022) Stabilization of heavy metals from lead-zinc ore tailings with sodium diethyl dithiocarbamate functionalized montmorillonite (DDTC-Mt): Leaching characteristics and remediating mechanism. MINERALS ENGINEERING, 183 (107608). [PMID:]
16. Xiu Liu, Junli Pu, Jianming Li, Bolin Gong. (2022) Preparation and performance analysis of monodisperse glycidyl methacrylate modified restricted access media-imprinted materials. JOURNAL OF SEPARATION SCIENCE, 45 (4): (976-983). [PMID:34933417]
17. Yating Zhang, Shujie Zhang, Lisong Fu, Mengke Jing. (2021) Study on antibacterial and copper ion removal of chitosan fiber/acetate fiber and yarn for water purification. Journal of Engineered Fibers and Fabrics, [PMID:]
18. Hui Li, Mingjun Li, Feng Zheng, Jing Wang, Lai Chen, Pengfei Hu, Qiang Zhen, Sajid Bashir, Jingbo Louise Liu. (2021) Efficient removal of water pollutants by hierarchical porous zeolite-activated carbon prepared from coal gangue and bamboo. Journal of Cleaner Production, 325 (129322). [PMID:]
19. Xiaoxiao Wang,Huachun Liu,Zhian Sun,Shanwen Zhao,Yanqiang Zhou,Jianmin Li,Tianpei Cai,Bolin Gong. (2020-06-25) Monodisperse restricted access material with molecularly imprinted surface for selective solid-phase extraction of 17β-estradiol from milk.. Journal of separation science, 43 ((17)): (3520-3533). [PMID:32579267]

References

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22. Yasuo Yoshimi,Noriyuki Ishii. (2015-02-16) Improved gate effect enantioselectivity of phenylalanine-imprinted polymers in water by blending crosslinkers.. Analytica chimica acta, 862 (77-85). [PMID:25682431]
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30. Sujuan Li, Haoqi Wu, Yuhang Sang, Bingtao Wang. (2019) Photoelectrochemical Non-Enzymatic Detection of Glucose at Graphene Supported CdS Nanowires via Decoration of CuO Nanoparticles under visible light. International Journal of Electrochemical Science, 14 (10458). [PMID:]
31. Yuanyuan Jin, Jiabin Zhang, Yanteng Xu, Ke Yi, Fenfang Li, Huicong Zhou, Haixia Wang, Hon Fai Chan, Yeh-Hsing Lao, Shixian Lv, Yu Tao, Mingqiang Li. (2023) Stem cell-derived hepatocyte therapy using versatile biomimetic nanozyme incorporated nanofiber-reinforced decellularized extracellular matrix hydrogels for the treatment of acute liver failure. Bioactive Materials, 28 (112). [PMID:37250866]
32. Ziyun Zhong, Hao Fu, Siyuan Wang, Yingnan Duan, Qinglun Wang, Chun-Hua Yan, Yaping Du. (2023) A Universal Synthesis Strategy for Lanthanide Sulfide Nanocrystals with Efficient Photocatalytic Hydrogen Production. Small, 19 (33): (2301392). [PMID:37086136]
33. Chen Xiao, Jiayuan Li, Xing Wang, Shiyou Li, Chen Xu, Zhijie Zhang, Ao Hua, Ze-yang Ding, Bi-xiang Zhang, Xiangliang Yang, Zifu Li. (2023) Hydroxyethyl starch stabilized copper-diethyldithiocarbamate nanocrystals for cancer therapy. JOURNAL OF CONTROLLED RELEASE, 356 (288). [PMID:36870542]
34. Wentao Dang, Yuqin Wang, Wei-Chih Chen, Enguo Ju, Rachel L. Mintz, Yue Teng, Lili Zhu, Kun Wang, Shixian Lv, Hon Fai Chan, Yu Tao, Mingqiang Li. (2023) Implantable 3D Printed Hydrogel Scaffolds Loading Copper-Doxorubicin Complexes for Postoperative Chemo/Chemodynamic Therapy. ACS Applied Materials & Interfaces, 15 (4): (4911–4923). [PMID:36656977]
35. Wendong Xing, Zhongfei Ma, Chong Wang, Jia Gao, Chao Yu, Yongsheng Yan, Li Yan, Chunxiang Li, Yilin Wu. (2023) Hierarchically porous molecularly imprinted membranes with multiple transfer channels for micropollutants selective separation. DESALINATION, 547 (116226). [PMID:]
36. Yafei Zhen, Tao Lin, Hanjiao Chen, Jing Hu, Xiandeng Hou. (2022) Vapor Generation of Rare-Earth Elements via Reaction with Tetrahydroborate: Chemical Identities and Mechanisms of Formation. ANALYTICAL CHEMISTRY, 94 (44): (15176–15182). [PMID:36301518]
37. Wenhao Li, De-Kun Ma, Xia Hu, Faliang Gou, Xiaogang Yang, Walker MacSwain, ChenZe Qi, Weiwei Zheng. (2022) General strategy for enhanced CH4 selectivity in photocatalytic CO2 reduction reactions by surface oxophilicity engineering. JOURNAL OF CATALYSIS, 415 (77). [PMID:]
38. Yao Lu, Qingqing Pan, Wenxia Gao, Yuji Pu, Bin He. (2022) Reversal of cisplatin chemotherapy resistance by glutathione-resistant copper-based nanomedicine via cuproptosis. Journal of Materials Chemistry B, 10 (33): (6296-6306). [PMID:35904024]
39. Kexin Bian, Weitao Yang, Yan Xu, Weiwei Zeng, Hui Wang, Hongying Liang, Tianming Cui, Zhuo Wang, Bingbo Zhang. (2022) Specific-Tuning Band Structure in Hetero-Semiconductor Nanorods to Match with Reduction of Oxygen Molecules for Low-Intensity Yet Highly Effective Sonodynamic/Hole Therapy of Tumors. Small, 18 (31): (2202921). [PMID:35801484]
40. Yali Liu, Wanchun Xiang, Shaiqiang Mou, Hao Zhang, Shengzhong Liu. (2022) Synergetic surface defect passivation towards efficient and stable inorganic perovskite solar cells. CHEMICAL ENGINEERING JOURNAL, 447 (137515). [PMID:]
41. Juxin Yin, Jianjian Zhuang, Xin Zhang, Chaojian Xu, Shaowu Lv. (2022) Ginseng of different ages is affected by the accumulation of heavy metals in ginseng soil. PLoS One, 17 (6): (e0269238). [PMID:35696360]
42. Huizhen Xiao, Guifang Wang, Guangchuan Liang, Jinliang Zhu, Jun Qiu, Chenhui Ding, Sridhar Komarneni. (2022) Stabilization of heavy metals from lead-zinc ore tailings with sodium diethyl dithiocarbamate functionalized montmorillonite (DDTC-Mt): Leaching characteristics and remediating mechanism. MINERALS ENGINEERING, 183 (107608). [PMID:]
43. Xiu Liu, Junli Pu, Jianming Li, Bolin Gong. (2022) Preparation and performance analysis of monodisperse glycidyl methacrylate modified restricted access media-imprinted materials. JOURNAL OF SEPARATION SCIENCE, 45 (4): (976-983). [PMID:34933417]
44. Yating Zhang, Shujie Zhang, Lisong Fu, Mengke Jing. (2021) Study on antibacterial and copper ion removal of chitosan fiber/acetate fiber and yarn for water purification. Journal of Engineered Fibers and Fabrics, [PMID:]
45. Hui Li, Mingjun Li, Feng Zheng, Jing Wang, Lai Chen, Pengfei Hu, Qiang Zhen, Sajid Bashir, Jingbo Louise Liu. (2021) Efficient removal of water pollutants by hierarchical porous zeolite-activated carbon prepared from coal gangue and bamboo. Journal of Cleaner Production, 325 (129322). [PMID:]
46. Xiaoxiao Wang,Huachun Liu,Zhian Sun,Shanwen Zhao,Yanqiang Zhou,Jianmin Li,Tianpei Cai,Bolin Gong. (2020-06-25) Monodisperse restricted access material with molecularly imprinted surface for selective solid-phase extraction of 17β-estradiol from milk.. Journal of separation science, 43 ((17)): (3520-3533). [PMID:32579267]

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