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Sodium metabisulfite - puriss., meets analytical specification of Ph. Eur., BP, NF, FCC, E223, dry, 97-100.5%, high purity , CAS No.7681-57-4

  • BP
  • NF
  • Ph.Eur.
  • puriss.
  • ≥97%
  • dry
Item Number
S433807
Grouped product items
SKUSizeAvailabilityPrice Qty
S433807-500g
500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$44.90

Basic Description

SynonymsSodium metabisulfite|7681-57-4|Sodium pyrosulfite|Sodium disulfite|Disodium pyrosulfite|Sodium metabisulphite|Disulfurous acid, disodium salt|Disodium disulphite|Natrii disulfis|Campden Tablets|Disodium metabisulfite|Disodium disulfite|Natrium pyrosulfit|
Specifications & Puritypuriss., meets analytical specification of Ph. Eur., BP, NF, FCC, E223, dry, 97-100.5%
GradeBP, NF, Ph.Eur., puriss.
Product Description

Sodium metabisulfite (MBS, Sodium disulfite) is an inorganic salt. It is the sodium salt of disulphurous (pyrosulfurous) acid. It is widely used as reducing agent in textile and photography industry. It is commonly added to various foods and wines as preservative.


Application

Sodium metabisulfite was used to initiate the cross-linking of polybutadiene in the cores of the vesicle membranes by free radical polymerization in solution. It has been used to prevent the oxidation (as antioxidant) during the preparation of stock solutions of 6-hydroxydopamine in various studies.

Names and Identifiers

INCHI InChI=1S/2Na.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2
InChi Key HRZFUMHJMZEROT-UHFFFAOYSA-L
Canonical SMILES [O-]S(=O)S(=O)(=O)[O-].[Na+].[Na+]
Isomeric SMILES [O-]S(=O)S(=O)(=O)[O-].[Na+].[Na+]
WGK Germany 1
RTECS UX8225000
PubChem CID 656671
UN Number 1759
Packing Group I
Molecular Weight 190.11

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SensitivityAir & Moisture sensitive
Boil Point(°C)150°C
Melt Point(°C)>300 °C

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07
Signal Danger
Hazard Statements

H302:Harmful if swallowed

H318:Causes serious eye damage

H402:Harmful to aquatic life

Precautionary Statements

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P301+P312+P330:IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.

WGK Germany 1
RTECS UX8225000
Class 8

Related Documents

References

1. W Wright,Y G Zhang,C M Salome,A J Woolcock.  (1990-06-01)  Effect of inhaled preservatives on asthmatic subjects. I. Sodium metabisulfite..  The American review of respiratory disease,  141  ((6)): (1400-1404).  [PMID:2161625]
2. Johanne Louise Neiiendam,Lene Boding Køhler,Claus Christensen,Shizhong Li,Martin Volmer Pedersen,Dorte Kornerup Ditlevsen,Martin Kirkegaard Kornum,Vladislav V Kiselyov,Vladimir Berezin,Elisabeth Bock.  (2004-11-05)  An NCAM-derived FGF-receptor agonist, the FGL-peptide, induces neurite outgrowth and neuronal survival in primary rat neurons..  Journal of neurochemistry,  91  ((4)): (920-935).  [PMID:15525346]
3. Zhiliang Cheng,Andrew Tsourkas.  (2008-06-24)  Paramagnetic porous polymersomes..  Langmuir : the ACS journal of surfaces and colloids,  24  ((15)): (8169-8173).  [PMID:18570445]
4. S Dänicke,M Beyer,G Breves,H Valenta,H-U Humpf.  (2010-08-03)  Effects of oral exposure of pigs to deoxynivalenol (DON) sulfonate (DONS) as the non-toxic derivative of DON on tissue residues of DON and de-epoxy-DON and on DONS blood levels..  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment,  27  ((11)): (1558-1565).  [PMID:20677033]
5. Nihal Ozturk,Piraye Yargicoglu,Narin Derin,Deniz Akpinar,Aysel Agar,Mutay Aslan.  (2010-09-30)  Dose-dependent effect of nutritional sulfite intake on visual evoked potentials and lipid peroxidation..  Neurotoxicology and teratology,  33  ((2)): (244-254).  [PMID:20875852]
6. Ozlem Ozsoy,Gulay Hacioglu,Feyza Savcioglu,Vural Kucukatay,Piraye Yargicoglu,Aysel Agar.  (2010-10-01)  The effect of sodium metabisulphite on active avoidance performance in hypercholesterolemic rats..  Environmental toxicology,  27  ((8)): (453-460).  [PMID:20882594]
7. Ivana Mara da Costa Machado Matos Carvalho,Ana Amélia Melo Cavalcante,Alisson Ferreira Dantas,Danilo Leôncio Aguiar Pereira,Francisco Cézar Costa Rocha,Francisco Massal de Oliveira,Juliana Da Silva.  (2010-11-09)  Environmental mutagenicity and toxicity caused by sodium metabisulfite in sea shrimp harvesting in Piauí, Brazil..  Chemosphere,  82  ((7)): (1056-1061).  [PMID:21056453]
8. Gisela Palma-Orozco,Alicia Ortiz-Moreno,Lidia Dorantes-Alvarez,José G Sampedro,Hugo Nájera.  (2010-11-23)  Purification and partial biochemical characterization of polyphenol oxidase from mamey (Pouteria sapota)..  Phytochemistry,  72  ((1)): (82-88).  [PMID:21087780]
9. Ivana M C M M Carvalho,Ana A C Melo Cavalcante,Alisson F Dantas,Danilo L A Pereira,Francisco C Costa Rocha,Teresinha J A S Andrade,Juliana Da Silva.  (2010-12-28)  Genotoxicity of sodium metabisulfite in mouse tissues evaluated by the comet assay and the micronucleus test..  Mutation research,  720  ((1-2)): (58-61).  [PMID:21185391]
10. Feyza Savcioglu,Ozlem Ozsoy,Gulay Hacioglu,Vural Kucukatay,Piraye Yargicoglu,Aysel Agar.  (2011-04-06)  The effect of sodium metabisulfite on visual evoked potentials in rats with hypercholesterolemia..  Toxicology mechanisms and methods,  21  ((6)): (479-486).  [PMID:21463131]
11. Rosie F Davies,Graham A Johnston.  (2011-04-19)  New and emerging cosmetic allergens..  Clinics in dermatology,  29  ((3)): (311-315).  [PMID:21496740]
12. Ilgaz Akdogan,Erdogan Kocamaz,Vural Kucukatay,Nilufer Goksin Yonguc,Mehmet Bulent Ozdemir,William Murk.  (2011-04-23)  Hippocampal neuron number loss in rats exposed to ingested sulfite..  Toxicology and industrial health,  27  ((9)): (771-778).  [PMID:21511899]
13. I U Nieves,C C Geddes,M T Mullinnix,R W Hoffman,Z Tong,E Castro,K T Shanmugam,L O Ingram.  (2011-05-03)  Injection of air into the headspace improves fermentation of phosphoric acid pretreated sugarcane bagasse by Escherichia coli MM170..  Bioresource technology,  102  ((13)): (6959-6965).  [PMID:21531547]
14. D Gutiérrez,A Foncubierta,R Espinosa,S Astorga,A Leon,S Fernández.  (2011-07-05)  Immediate type 1 hypersensitivity to apomorphine: a case report..  Journal of investigational allergology & clinical immunology,  21  ((4)): (325-326).  [PMID:21721386]
15. Jiafu Feng,Xiancheng Zhana,Shiwen Qiaob,Chaojun Wub,Longxiang Xiaob.  (2011-08-05)  A mathematical model for calculating the shelf life of ascorbic acid solution under given conditions..  Drug development and industrial pharmacy,  38  ((3)): (264-270).  [PMID:21812540]
16. Katsura Hohtatsu,Ken Yamaji,Risa Yamada,Keisuke Oda,Michiaki Kageyama,Makio Kusaoi,Shin Onuma,Toshio Kawamoto,Kaoru Sugimoto,Fumio Sekiya,Takayuki Kon,Michihiro Ogasawara,Kazuo Kempe,Hiroshi Tsuda,Yoshinari Takasaki.  (2011-09-03)  Effect of various anticoagulant agents on large-volume leukocytapheresis using new Cellsorba CS-180S Filter..  Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy,  15  ((4)): (355-359).  [PMID:21884469]
17. Marzena Podolska,Wanda Białecka,Anna Kulik,Barbara Kwiatkowska-Puchniarz,Aleksander Mazurek.  (2011-09-21)  Determination of sodium metabisulfite in parenteral formulations by HPIC with suppressed conductivity detection..  Acta poloniae pharmaceutica,  68  ((5)): (637-644).  [PMID:21928707]
18. David W Roberts,David Basketter,Ian Kimber,Jonathan White,John McFadden,Ian R White.  (2012-02-11)  Sodium metabisulfite as a contact allergen--an example of a rare chemical mechanism for protein modification..  Contact dermatitis,  66  ((3)): (123-127).  [PMID:22320665]
19. Thomas Oliphant,Angana Mitra,Mark Wilkinson.  (2012-02-11)  Contact allergy to sodium sulfite and its relationship to sodium metabisulfite..  Contact dermatitis,  66  ((3)): (128-130).  [PMID:22320666]
20. Sri Awalia Febriana,Frank Jungbauer,Hardyanto Soebono,Pieter-Jan Coenraads.  (2012-05-11)  Occupational allergic contact dermatitis and patch test results of leather workers at two Indonesian tanneries..  Contact dermatitis,  67  ((5)): (277-283).  [PMID:22571396]
21. Jeffrey N Hemenway,Thiago C Carvalho,Venkatramana M Rao,Yongmei Wu,Jaquan K Levons,Ajit S Narang,Srinivasa R Paruchuri,Howard J Stamato,Sailesh A Varia.  (2012-05-23)  Formation of reactive impurities in aqueous and neat polyethylene glycol 400 and effects of antioxidants and oxidation inducers..  Journal of pharmaceutical sciences,  101  ((9)): (3305-3318).  [PMID:22610374]
22. Orlando B S Galli,Rodrigo Y Fujimoto,Fernando A Abrunhosa.  (2012-05-31)  Acute toxicity of sodium metabisulphite in larvae and post-larvae of the land crab, Cardisoma guanhumi..  Bulletin of environmental contamination and toxicology,  89  ((2)): (274-280).  [PMID:22644045]
23. Zhenhua Yang,Yuexia Zhang,Ziqiang Meng.  (2012-06-26)  The vasodilator mechanisms of sodium metabisulfite on precontracted isolated aortic rings in rats: signal transduction pathways and ion channels..  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,  50  ((9)): (3114-3119).  [PMID:22727858]
24. Adriana B Pedale,Rodrigo Y Fujimoto,Rudã F B Santos,Fernando A Abrunhosa.  (2012-09-20)  Acute toxicity of sodium metabisulphite on mangrove crab Ucides cordatus (Decapoda, Ucididae)..  Anais da Academia Brasileira de Ciencias,  84  ((4)): (1009-1014).  [PMID:22990601]
25. Juan García-Gavín,Joana Parente,An Goossens.  (2012-10-09)  Allergic contact dermatitis caused by sodium metabisulfite: a challenging allergen: a case series and literature review..  Contact dermatitis,  67  ((5)): (260-269).  [PMID:23039002]
26. Ceren Kencebay,Narin Derin,Ozlem Ozsoy,Dijle Kipmen-Korgun,Gamze Tanriover,Nihal Ozturk,Goksun Basaranlar,Piraye Yargicoglu-Akkiraz,Berna Sozen,Aysel Agar.  (2012-11-22)  Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain..  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,  52  (129-136).  [PMID:23168241]
27. Sven Dänicke,Susanne Kersten,Hana Valenta,Gerhard Breves.  (2013-04-23)  Inactivation of deoxynivalenol-contaminated cereal grains with sodium metabisulfite: a review of procedures and toxicological aspects..  Mycotoxin research,  28  ((4)): (199-218).  [PMID:23606192]
28. Sarah Bradbury,Judith Bird,Joyce Colussi-Mas,Melanie Mueller,George Ricaurte,Susan Schenk.  (2013-06-15)  Acquisition of MDMA self-administration: pharmacokinetic factors and MDMA-induced serotonin release..  Addiction biology,  19  ((5)): (874-884).  [PMID:23763615]
29. Saeed Shojaee,Ali Nokhodchi,Iain Cumming.  (2013-08-22)  The role of fillers and sodium metabisulfite on drug release from aged polyox tablets..  Drug development and industrial pharmacy,  40  ((11)): (1451-1458).  [PMID:23962147]
30. Dhaval R Kalaria,Pratikkumar Patel,Virginia Merino,Vandana B Patravale,Yogeshvar N Kalia.  (2014-02-15)  Controlled iontophoretic delivery of pramipexole: electrotransport kinetics in vitro and in vivo..  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V,  88  ((1)): (56-63).  [PMID:24525072]
31. Neal Luther,Zhiping Zhou,Pat Zanzonico,Nai-Kong Cheung,John Humm,Mark A Edgar,Mark M Souweidane.  (2014-02-15)  The potential of theragnostic ¹²⁴I-8H9 convection-enhanced delivery in diffuse intrinsic pontine glioma..  Neuro-oncology,  16  ((6)): (800-806).  [PMID:24526309]
32. Imola Plangár,Dénes Zádori,Levente Szalárdy,László Vécsei,Péter Klivényi.  (2014-02-22)  Assessment of the role of multidrug resistance-associated proteins in MPTP neurotoxicity in mice..  Ideggyogyaszati szemle,  66  ((11-12)): (407-414).  [PMID:24555241]
33. Wendell Ho-Tin Law,Kam-Keung Leung,Lawrence Cho-Cheung Lee,Che-Shan Poon,Hua-Wei Liu,Kenneth Kam-Wing Lo.  (2014-03-20)  Cyclometalated iridium(III) bipyridyl-phenylenediamine complexes with multicolor phosphorescence: synthesis, electrochemistry, photophysics, and intracellular nitric oxide sensing..  ChemMedChem,  ((6)): (1316-1329).  [PMID:24643988]
34. Prakash Tiwari,Krishna P Gupta.  (2014-05-06)  Modulation of miR-203 and its regulators as a function of time during the development of 7, 12 dimethylbenz [a] anthracene induced mouse skin tumors in presence or absence of the antitumor agents..  Toxicology and applied pharmacology,  278  ((2)): (148-158).  [PMID:24792773]
35. Wen-Bo Deng,Xiao-Huan Liang,Ji-Long Liu,Zeng-Ming Yang.  (2014-05-07)  Regulation and function of deiodinases during decidualization in female mice..  Endocrinology,  155  ((7)): (2704-2717).  [PMID:24797630]
36. Natalia Mosconi,Cecilia Giulidori,Francesca Velluti,Estela Hure,Agustina Postigo,Graciela Borthagaray,Davi Fernando Back,María H Torre,Marcela Rizzotto.  (2014-05-09)  Antibacterial, antifungal, phytotoxic, and genotoxic properties of two complexes of Ag(I) with sulfachloropyridazine (SCP): X-ray diffraction of [Ag(SCP)]n..  ChemMedChem,  ((6)): (1211-1220).  [PMID:24806993]
37. Elena Pérez,Ana Martínez,César Teijón,Jose M Teijón,M Dolores Blanco.  (2014-05-13)  Bioresponsive nanohydrogels based on HEAA and NIPA for poorly soluble drugs delivery..  International journal of pharmaceutics,  470  ((1-2)): (107-119).  [PMID:24813784]
38. M P Do,C Neut,E Delcourt,T Seixas Certo,J Siepmann,F Siepmann.  (2014-05-17)  In situ forming implants for periodontitis treatment with improved adhesive properties..  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V,  88  ((2)): (342-350).  [PMID:24833006]
39. Maria A Vlasova,Jussi Rytkönen,Joakim Riikonen,Olga S Tarasova,Juha Mönkäre,Miia Kovalainen,Ale Närvänen,Jarno Salonen,Karl-Heinz Herzig,Vesa-Pekka Lehto,Kristiina Järvinen.  (2014-06-26)  Nanocarriers and the delivered drug: effect interference due to intravenous administration..  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences,  63  (96-102).  [PMID:24964293]
40. Rahul Sonawane,Harshad Harde,Mahesh Katariya,Satyam Agrawal,Sanyog Jain.  (2014-08-01)  Solid lipid nanoparticles-loaded topical gel containing combination drugs: an approach to offset psoriasis..  Expert opinion on drug delivery,  11  ((12)): (1833-1847).  [PMID:25078031]
41. P Abate,K Hernández-Fonseca,A C Reyes-Guzmán,I G Barbosa-Luna,M Méndez.  (2014-08-26)  Prenatal ethanol exposure alters met-enkephalin expression in brain regions related with reinforcement: possible mechanism for ethanol consumption in offspring..  Behavioural brain research,  274  (194-204).  [PMID:25150040]
42. Bidyadhar Mandal,Samit Kumar Ray.  (2014-10-05)  Swelling, diffusion, network parameters and adsorption properties of IPN hydrogel of chitosan and acrylic copolymer..  Materials science & engineering. C, Materials for biological applications,  44  (132-143).  [PMID:25280689]
43. Ping Chu,Aimee L Cunningham,Jieh-Juen Yu,Jesse Q Nguyen,Jeffrey R Barker,C Rick Lyons,Julie Wilder,Michelle Valderas,Robert L Sherwood,Bernard P Arulanandam,Karl E Klose.  (2014-10-24)  Live attenuated Francisella novicida vaccine protects against Francisella tularensis pulmonary challenge in rats and non-human primates..  PLoS pathogens,  10  ((10)): (e1004439-e1004439).  [PMID:25340543]
44. Hadis Honarvar,Javad Garousi,Elin Gunneriusson,Ingmarie Höidén-Guthenberg,Mohamed Altai,Charles Widström,Vladimir Tolmachev,Fredrik Y Frejd.  (2014-12-02)  Imaging of CAIX-expressing xenografts in vivo using 99mTc-HEHEHE-ZCAIX:1 affibody molecule..  International journal of oncology,  46  ((2)): (513-520).  [PMID:25434612]
45. Lubica Horvathova,Andrej Tillinger,Ivana Sivakova,Lucia Mikova,Boris Mravec,Maria Bucova.  (2014-12-04)  Chemical sympathectomy increases neutrophil-to-lymphocyte ratio in tumor-bearing rats but does not influence cancer progression..  Journal of neuroimmunology,  278  (255-261).  [PMID:25468774]
46. Maria Addolorata Saracino,Laura Santarcangelo,Maria Augusta Raggi,Laura Mercolini.  (2014-12-17)  Microextraction by packed sorbent (MEPS) to analyze catecholamines in innovative biological samples..  Journal of pharmaceutical and biomedical analysis,  104  (122-129).  [PMID:25497894]
47. Melinda A Engevik,Mary Beth Yacyshyn,Kristen A Engevik,Jiang Wang,Benjamin Darien,Daniel J Hassett,Bruce R Yacyshyn,Roger T Worrell.  (2015-01-02)  Human Clostridium difficile infection: altered mucus production and composition..  American journal of physiology. Gastrointestinal and liver physiology,  308  ((6)): (G510-G524).  [PMID:25552581]
48. Carole Laffont,Thomas Rey,Olivier André,Mara Novero,Théophile Kazmierczak,Frédéric Debellé,Paola Bonfante,Christophe Jacquet,Florian Frugier.  (2015-01-07)  The CRE1 cytokinin pathway is differentially recruited depending on Medicago truncatula root environments and negatively regulates resistance to a pathogen..  PloS one,  10  ((1)): (e0116819-e0116819).  [PMID:25562779]
49. Yan-Fang Tao,Li-Xiao Xu,Jun Lu,Shao-Yan Hu,Fang Fang,Lan Cao,Pei-Fang Xiao,Xiao-Juan Du,Li-Chao Sun,Zhi-Heng Li,Na-Na Wang,Guang-Hao Su,Yan-Hong Li,Gang Li,He Zhao,Yi-Ping Li,Yun-Yun Xu,Hui-Ting Zhou,Yi Wu,Mei-Fang Jin,Lin Liu,Xue-Ming Zhu,Jian Ni,Jian Wang,Feng Xing,Wen-Li Zhao,Jian Pan.  (2015-01-23)  Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia..  Journal of experimental & clinical cancer research : CR,  34  (4-4).  [PMID:25609158]
50. Robert Schlegl,Michael Weber,Jürgen Wruss,Donald Low,Kirsten Queen,Shaun Stilwell,Erik B Lindblad,Michael Möhlen.  (2015-06-23)  Influence of elemental impurities in aluminum hydroxide adjuvant on the stability of inactivated Japanese Encephalitis vaccine, IXIARO®..  Vaccine,  33  ((44)): (5989-5996).  [PMID:26095510]
51. Evelien Wynendaele,Frederick Verbeke,Sofie Stalmans,Bert Gevaert,Yorick Janssens,Christophe Van De Wiele,Kathelijne Peremans,Christian Burvenich,Bart De Spiegeleer.  (2015-11-05)  Quorum Sensing Peptides Selectively Penetrate the Blood-Brain Barrier..  PloS one,  10  ((11)): (e0142071-e0142071).  [PMID:26536593]
52. S A Kim,S H Jeon,N H Kim,H W Kim,N Y Lee,T J Cho,Y M Jung,S H Lee,I G Hwang,M S Rhee.  (2015-11-29)  Changes in the Microbial Composition of Microbrewed Beer during the Process in the Actual Manufacturing Line..  Journal of food protection,  78  ((12)): (2233-2239).  [PMID:26613919]
53. Laurie H L Sellings,Paul B S Clarke.  (2003-07-18)  Segregation of amphetamine reward and locomotor stimulation between nucleus accumbens medial shell and core..  The Journal of neuroscience : the official journal of the Society for Neuroscience,  23  ((15)): (6295-6303).  [PMID:12867514]

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