Click Here for 5% Off Your First Aladdin Purchase!

Sodium phosphate tribasic dodecahydrate - ACS, ≥98%, high purity , CAS No.10101-89-0

  • ACS
  • ≥98%
Item Number
S112443
Grouped product items
SKUSizeAvailabilityPrice Qty
S112443-500g
500g
In stock
$96.90

Basic Description

SynonymsTrisodium phosphate dodecahydrate|10101-89-0|Sodium phosphate tribasic dodecahydrate|Sodium phosphate dodecahydrate|Phosphoric acid, trisodium salt, dodecahydrate|sodium phosphate, tribasic, dodecahydrate|CCRIS 7322|Phosphoric acid, trisodium salt, dodeah
Specifications & PurityACS, ≥98%
Shipped InNormal
GradeACS
Product Description

Sodium phosphate tribasic dodecahydrate is also known as trisodium phospate or TSP. It is highly soluble in water and widely used as a cleaning agent. The pH of a 1% solution is typically around 12, making this reagent sufficiently alkaline for saponification of grease and oils. Often used in the formulation of various buffers; complementary buffer components may include: Sodium phosphate monobasic, Sodium phosphate dibasic or Potassium Phosphate, Dibasic. Trisodium phosphate is used in the isolation of mycobacteria, including culturing of tubercle bacilli. Has been used as a protein precipitant in certain applications and in co-precipitation and fractionization of nucleotides. May be used for the preservation of biologically active soil samples. Because of the alkaline pH, TSP disrupts cytoplasmic and outer membranes of Salmonella enterica cells making it useful in preventing the spread of bacteria.
Often used in the formulation of various buffers

Names and Identifiers

IUPAC Name trisodium;phosphate;dodecahydrate
INCHI InChI=1S/3Na.H3O4P.12H2O/c;;;1-5(2,3)4;;;;;;;;;;;;/h;;;(H3,1,2,3,4);12*1H2/q3*+1;;;;;;;;;;;;;/p-3
InChi Key ASTWEMOBIXQPPV-UHFFFAOYSA-K
Canonical SMILES O.O.O.O.O.O.O.O.O.O.O.O.[O-]P(=O)([O-])[O-].[Na+].[Na+].[Na+]
Isomeric SMILES O.O.O.O.O.O.O.O.O.O.O.O.[O-]P(=O)([O-])[O-].[Na+].[Na+].[Na+]
WGK Germany 1
RTECS TC9575000
PubChem CID 61473
UN Number 3262
Packing Group I
Molecular Weight 380.12

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot NumberCertificate TypeDateItem
B23271000Certificate of AnalysisNov 07, 2022 S112443
B2327879Certificate of AnalysisNov 07, 2022 S112443
F2204615Certificate of AnalysisMar 09, 2022 S112443
F2204618Certificate of AnalysisMar 09, 2022 S112443

Chemical and Physical Properties

SolubilitySoluble in water (258 mg/ml at 20 °C). Insoluble in alcohol.,
SensitivityMoisture sensitive.
Melt Point(°C)75°C

Safety and Hazards(GHS)

Pictogram(s) GHS05,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H314:Causes severe skin burns and eye damage

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P271:Use only outdoors or in a well-ventilated area.

P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P363:Wash contaminated clothing before reuse.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

WGK Germany 1
RTECS TC9575000
Class 8

Related Documents

References

1. Koh S et al..  (2015)  Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins..  J Neurosci,  35  (47): (15649-65).  [PMID:26609158]
2. Inkyu Park,Zhiyong Li,Xuema Li,Albert P Pisano,R Stanley Williams.  (2006-10-24)  Towards the silicon nanowire-based sensor for intracellular biochemical detection..  Biosensors & bioelectronics,  22  ((9-10)): (2065-2070).  [PMID:17056246]
3. Lijuan Song,Zhenpeng Guo,Yi Chen.  (2012-07-19)  Separation and determination of chiral composition in penicillamine tablets by capillary electrophoresis in a broad pH range..  Electrophoresis,  33  ((13)): (2056-2063).  [PMID:22806473]
4. Hannah N Ladenhauf,Ottokar Stundner,Florian Spreitzhofer,Stefan Deluggi.  (2012-07-24)  Severe hyperphosphatemia after administration of sodium-phosphate containing laxatives in children: case series and systematic review of literature..  Pediatric surgery international,  28  ((8)): (805-814).  [PMID:22820833]
5. Andrew Connor,Damian Tolan,Stephen Hughes,Nick Carr,Charles Tomson.  (2012-07-31)  Consensus guidelines for the safe prescription and administration of oral bowel-cleansing agents..  Gut,  61  ((11)): (1525-1532).  [PMID:22842619]
6. Pei-Yu Liu,Yi-Hui Lin,Chia Hsien Feng,Yen-Ling Chen.  (2012-09-22)  Determination of hydroxy acids in cosmetics by chemometric experimental design and cyclodextrin-modified capillary electrophoresis..  Electrophoresis,  33  ((19-20)): (3079-3086).  [PMID:22996609]
7. Kelong Wang,Dechen Jiang,Christopher E Sims,Nancy L Allbritton.  (2012-09-25)  Separation of fluorescently labeled phosphoinositides and sphingolipids by capillary electrophoresis..  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,  907  (79-86).  [PMID:23000742]
8. Yuqin Li,Yingjie Cui,Baoxiu Jia,Hao Wang,Caihong Liu,Yongxiu Qi.  (2012-09-29)  Capillary electrophoresis with field-amplified sample stacking for rapid and sensitive determination of sulfadiazine and sulfamethoxazole..  Die Pharmazie,  67  ((9)): (768-773).  [PMID:23016449]
9. Samuel Adler,Cesare Hassan,Yoav Metzger,Yishai Sompolinsky,Cristiano Spada.  (2012-10-03)  Accuracy of automatic detection of small-bowel mucosa by second-generation colon capsule endoscopy..  Gastrointestinal endoscopy,  76  ((6)): (1170-1174).  [PMID:23025975]
10. Alicia Alonso-Hernando,Rosa Capita,Carlos Alonso-Calleja.  (2012-10-18)  Behaviour of co-inoculated pathogenic and spoilage bacteria on poultry following several decontamination treatments..  International journal of food microbiology,  159  ((2)): (152-159).  [PMID:23072701]
11. I C Lawrance,R P Willert,K Murray.  (2012-10-26)  A validated bowel-preparation tolerability questionnaire and assessment of three commonly used bowel-cleansing agents..  Digestive diseases and sciences,  58  ((4)): (926-935).  [PMID:23095990]
12. Dominika Szoke,Alberto Dolci,Augusto Genderini,Mauro Panteghini.  (2012-10-30)  Fatal electrolyte abnormalities following enema administration..  Clinical chemistry,  58  ((11)): (1515-1518).  [PMID:23104957]
13. Cameron P Brewer,Brian Dawson,Karen E Wallman,Kym J Guelfi.  (2012-11-02)  Effect of repeated sodium phosphate loading on cycling time-trial performance and VO2peak..  International journal of sport nutrition and exercise metabolism,  23  ((2)): (187-194).  [PMID:23114686]
14. Luca Casettari,Marco Cespi,Giovanni Filippo Palmieri,Giulia Bonacucina.  (2012-11-06)  Characterization of the interaction between chitosan and inorganic sodium phosphates by means of rheological and optical microscopy studies..  Carbohydrate polymers,  91  ((2)): (597-602).  [PMID:23121951]
15. Jonathan Belsey,Cristiano Crosta,Owen Epstein,Wolfgang Fischbach,Peter Layer,Fabrizio Parente,Marc Halphen.  (2012-11-10)  Meta-analysis: efficacy of small bowel preparation for small bowel video capsule endoscopy..  Current medical research and opinion,  28  ((12)): (1883-1890).  [PMID:23136911]
16. Ahmet Ozveren,Baris Akinci,Ozer Makay,Banu Sarsik,Ilgin Yildirim Simsir,Afig Berdeli,Mahir Akyildiz.  (2012-11-17)  A puzzling case of phospho-soda-induced hypocalcemia in a patient with multiple endocrine neoplasia type 1-associated primary hyperparathyroidism..  Internal medicine (Tokyo, Japan),  51  ((22)): (3145-3149).  [PMID:23154721]
17. Eduardo Coghlan,Luis Laferrere,Horacio Ayunta,María Lourdes Posadas Martínez,Jorge Javier Topor,Angel Nadales,Carlos González del Solar.  (2012-12-12)  [Bowel preparation for colonoscopy: comparative study using Boston Bowel Preparation Scale]..  Acta gastroenterologica Latinoamericana,  42  ((3)): (186-192).  [PMID:23214348]
18. Meital Aviv-Gavriel,Nissim Garti,Helga Füredi-Milhofer.  (2012-12-13)  Preparation of a partially calcified gelatin membrane as a model for a soft-to-hard tissue interface..  Langmuir : the ACS journal of surfaces and colloids,  29  ((2)): (683-689).  [PMID:23231089]
19. Edith Schir,Sophie Barbouy-des-Courières,François Plottin,Michel Mallaret.  (2012-12-18)  [Colokit(®) preparation (sodium phosphate) induced erosive gastritis]..  Therapie,  67  ((5)): (477-479).  [PMID:23241258]
20. L Zhong,M Oostrom,M J Truex,V R Vermeul,J E Szecsody.  (2012-12-19)  Rheological behavior of xanthan gum solution related to shear thinning fluid delivery for subsurface remediation..  Journal of hazardous materials,  244-245  (160-170).  [PMID:23246952]
21. .  (2013-01-26)  Colonoscopy preperations..  The Medical letter on drugs and therapeutics,  55  ((1408)): (6-6).  [PMID:23348359]
22. Austin C Lowder,Carla L Goad,Xingqiu Lou,J Brad Morgan,Chern Lin Koh,Alisha Parsons Deakins,Christina A Mireles DeWitt.  (2013-01-29)  Response surface modeling to predict fluid loss from beef strip loins and steaks injected with salt and phosphate with or without a dehydrated beef protein water binding adjunct..  Meat science,  94  ((1)): (9-18).  [PMID:23352982]
23. Mitsuru Abo,Li-Ping He,Kae Sato,Akira Okubo.  (2013-02-07)  Determination of monosaccharides derivatized with 2-aminobenzoic Acid by capillary electrophoresis..  Methods in molecular biology (Clifton, N.J.),  984  (45-50).  [PMID:23386335]
24. Chaoran Wang,Zhimou Guo,Zhen Long,Xiuli Zhang,Xinmiao Liang.  (2013-02-16)  Overloading study of basic compounds with a positively charged C18 column in liquid chromatography..  Journal of chromatography. A,  1281  (60-66).  [PMID:23411141]
25. Rosa Capita,Elena Alvarez-Fernández,Esther Fernández-Buelta,Jennifer Manteca,Carlos Alonso-Calleja.  (2013-03-19)  Decontamination treatments can increase the prevalence of resistance to antibiotics of Escherichia coli naturally present on poultry..  Food microbiology,  34  ((1)): (112-117).  [PMID:23498186]
26. L Boysen,N S Wechter,H Rosenquist.  (2013-04-11)  Effects of decontamination at varying contamination levels of Campylobacter jejuni on broiler meat..  Poultry science,  92  ((5)): (1425-1429).  [PMID:23571355]
27. Yi-Ling Hsieh,Lynne S Taylor.  (2014-08-26)  Salt stability--effect of particle size, relative humidity, temperature and composition on salt to free base conversion..  Pharmaceutical research,  32  ((2)): (549-561).  [PMID:25145335]
28. Lei Wei,Qing Wang,Huifeng Wu,Chenglong Ji,Jianmin Zhao.  (2014-09-02)  Proteomic and metabolomic responses of Pacific oyster Crassostrea gigas to elevated pCO2 exposure..  Journal of proteomics,  112  (83-94).  [PMID:25175059]
29. Yan Li,Yanli Wen,Lele Wang,Wen Liang,Li Xu,Shuzhen Ren,Ziying Zou,Xiaolei Zuo,Chunhai Fan,Qing Huang,Gang Liu,Nengqin Jia.  (2014-09-10)  Analysis of telomerase activity based on a spired DNA tetrahedron TS primer..  Biosensors & bioelectronics,  67  (364-369).  [PMID:25194236]
30. Chun-Yiu Law,Ching-Wan Lam,Chor-kwan Ching,Kin-Cheong Eric Yau,Tsz-wai Ho,Chi-kong Lai,Chloe Miu Mak.  (2014-09-10)  NMR-based urinalysis for beta-ketothiolase deficiency..  Clinica chimica acta; international journal of clinical chemistry,  438  (222-225).  [PMID:25195009]
31. Lucia A Possamai,Mark Jw McPhail,Wafa Khamri,Bishan Wu,Danilo Concas,Mark Harrison,Roger Williams,Roger D Cox,I Jane Cox,Quentin M Anstee,Mark R Thursz.  (2014-09-23)  The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity..  Liver international : official journal of the International Association for the Study of the Liver,  35  ((3)): (764-773).  [PMID:25244648]
32. Azza H Rageh,Ute Pyell.  (2014-09-27)  Boronate affinity-assisted MEKC separation of highly hydrophilic urinary nucleosides using imidazolium-based ionic liquid type surfactant as pseudostationary phase..  Electrophoresis,  36  ((5)): (784-795).  [PMID:25257361]
33. Ashley C Gucinski,Michael T Boyne,David A Keire.  (2014-09-28)  Modern analytics for naturally derived complex drug substances: NMR and MS tests for protamine sulfate from chum salmon..  Analytical and bioanalytical chemistry,  407  ((3)): (749-759).  [PMID:25260409]
34. Daniela Rigano,Carmen Formisano,Ester Pagano,Felice Senatore,Sonia Piacente,Milena Masullo,Raffaele Capasso,Angelo A Izzo,Francesca Borrelli.  (2014-10-07)  A new acetophenone derivative from flowers of Helichrysum italicum (Roth) Don ssp. italicum..  Fitoterapia,  99  (198-203).  [PMID:25285382]
35. Marie-France Penet,Tariq Shah,Santosh Bharti,Balaji Krishnamachary,Dmitri Artemov,Yelena Mironchik,Flonné Wildes,Anirban Maitra,Zaver M Bhujwalla.  (2014-11-06)  Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism..  Clinical cancer research : an official journal of the American Association for Cancer Research,  21  ((2)): (386-395).  [PMID:25370468]
36. Xiaoxia Yang,Dong Ren,Wenwen Sun,Xiaoman Li,Bin Huang,Rong Chen,Chan Lin,Xuejun Pan.  (2014-11-26)  Polycyclic aromatic hydrocarbons associated with total suspended particles and surface soils in Kunming, China: distribution, possible sources, and cancer risks..  Environmental science and pollution research international,  22  ((9)): (6696-6712).  [PMID:25422115]
37. Véronique Gilard,Stéphane Balayssac,Aurélie Tinaugus,Nathalie Martins,Robert Martino,Myriam Malet-Martino.  (2014-12-03)  Detection, identification and quantification by 1H NMR of adulterants in 150 herbal dietary supplements marketed for improving sexual performance..  Journal of pharmaceutical and biomedical analysis,  102  (476-493).  [PMID:25459948]
38. Jie Guo,Kuangfei Lin,Jingjing Deng,Xiaoxu Fu,Zhenming Xu.  (2014-12-03)  Polybrominated diphenyl ethers in indoor air during waste TV recycling process..  Journal of hazardous materials,  283  (439-446).  [PMID:25464281]
39. Maria D Cao,Santosh Lamichhane,Steinar Lundgren,Anna Bofin,Hans Fjøsne,Guro F Giskeødegård,Tone F Bathen.  (2014-12-17)  Metabolic characterization of triple negative breast cancer..  BMC cancer,  14  (941-941).  [PMID:25495193]
40. Dagmar Fuchs,Young de Graaf,Roeland van Kerckhoven,Richard Draijer.  (2014-12-17)  Effect of tea theaflavins and catechins on microvascular function..  Nutrients,  ((12)): (5772-5785).  [PMID:25514559]
41. Ekaterina Smirnova,Irina Safenkova,Vita Stein-Margolina,Vladimir Shubin,Vladimir Polshakov,Bella Gurvits.  (2014-12-21)  pH-responsive modulation of insulin aggregation and structural transformation of the aggregates..  Biochimie,  109  (49-59).  [PMID:25527324]
42. Jingping Liu,Chengshi Wang,Fang Liu,Yanrong Lu,Jingqiu Cheng.  (2015-02-01)  Metabonomics revealed xanthine oxidase-induced oxidative stress and inflammation in the pathogenesis of diabetic nephropathy..  Analytical and bioanalytical chemistry,  407  ((9)): (2569-2579).  [PMID:25636229]
43. Xiao Jiang,Rex E Jeffries,Miguel A Acosta,Andrey P Tikunov,Jeffrey M Macdonald,Glenn M Walker,Michael P Gamcsik.  (2015-02-06)  Biocompatibility of Tygon® tubing in microfluidic cell culture..  Biomedical microdevices,  17  ((1)): (20-20).  [PMID:25653072]
44. Ning Li,Limin Zhang,Yanpeng An,Lulu Zhang,Yipeng Song,Yulan Wang,Huiru Tang.  (2015-02-12)  Antagonist of prostaglandin E2 receptor 4 induces metabolic alterations in liver of mice..  Journal of proteome research,  14  ((3)): (1566-1573).  [PMID:25669961]
45. Ge Dong,Dandan Wei,Junsong Wang,Pingping Guo,Minghui Li,Minghua Yang,Lingyi Kong.  (2015-03-18)  Study of the cardiotoxicity of Venenum Bufonis in rats using an 1H NMR-based metabolomics approach..  PloS one,  10  ((3)): (e0119515-e0119515).  [PMID:25781638]
46. Nancy Witowski,Elizabeth Lusczek,Charles Determan,Daniel Lexcen,Kristine Mulier,Beverly Ostrowski,Greg Beilman.  (2015-04-16)  A four-compartment metabolomics analysis of the liver, muscle, serum, and urine response to polytrauma with hemorrhagic shock following carbohydrate prefeed..  PloS one,  10  ((4)): (e0124467-e0124467).  [PMID:25875111]
47. Audrey F Dumax-Vorzet,M Tate,Richard Walmsley,Rhod H Elder,Andrew C Povey.  (2015-06-27)  Cytotoxicity and genotoxicity of urban particulate matter in mammalian cells..  Mutagenesis,  30  ((5)): (621-633).  [PMID:26113525]
48. Pei Li,Dan-Dan Wei,Jun-Song Wang,Ming-Hua Yang,Ling-Yi Kong.  (2015-09-12)  (1)H NMR metabolomics to study the effects of diazepam on anisatin induced convulsive seizures..  Journal of pharmaceutical and biomedical analysis,  117  (184-194).  [PMID:26361344]
49. Marie Austdal,Line H Tangerås,Ragnhild B Skråstad,Kjell Salvesen,Rigmor Austgulen,Ann-Charlotte Iversen,Tone F Bathen.  (2015-09-16)  First Trimester Urine and Serum Metabolomics for Prediction of Preeclampsia and Gestational Hypertension: A Prospective Screening Study..  International journal of molecular sciences,  16  ((9)): (21520-21538).  [PMID:26370975]
50. Fay Probert,Victor Ruiz-Rodado,Xiaoyu Zhang,Danielle te Vruchte,Tim D W Claridge,Mark Edgar,Anna Zonato Tocchio,Robin H Lachmann,Frances M Platt,Martin Grootveld.  (2015-09-24)  Urinary excretion and metabolism of miglustat and valproate in patients with Niemann-Pick type C1 disease: One- and two-dimensional solution-state (1)H NMR studies..  Journal of pharmaceutical and biomedical analysis,  117  (276-288).  [PMID:26397207]
51. Alison J Hugill,Michelle E Stewart,Marianne A Yon,Fay Probert,I Jane Cox,Tertius A Hough,Cheryl L Scudamore,Liz Bentley,Gary Wall,Sara E Wells,Roger D Cox.  (2015-10-04)  Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance..  Biology open,  ((11)): (1367-1375).  [PMID:26432886]
52. Zhong-Wei Xu,Xi Chen,Xiao-Han Jin,Xiang-Yan Meng,Xin Zhou,Feng-Xu Fan,Shi-Yun Mao,Yue Wang,Wen-Cheng Zhang,Na-Na Shan,Yu-Ming Li,Rui-Cheng Xu.  (2015-10-06)  SILAC-based proteomic analysis reveals that salidroside antagonizes cobalt chloride-induced hypoxic effects by restoring the tricarboxylic acid cycle in cardiomyocytes..  Journal of proteomics,  130  (211-220).  [PMID:26435418]
53. Nur Ashikin Abdul-Hamid,Faridah Abas,Intan Safinar Ismail,Khozirah Shaari,Nordin H Lajis.  (2015-10-13)  Influence of Different Drying Treatments and Extraction Solvents on the Metabolite Profile and Nitric Oxide Inhibitory Activity of Ajwa Dates..  Journal of food science,  80  ((11)): (H2603-H2611).  [PMID:26457883]
54. Sarah Rogstad,Eric Pang,Cynthia Sommers,Meng Hu,Xiaohui Jiang,David A Keire,Michael T Boyne.  (2015-10-16)  Modern analytics for synthetically derived complex drug substances: NMR, AFFF-MALS, and MS tests for glatiramer acetate..  Analytical and bioanalytical chemistry,  407  ((29)): (8647-8659).  [PMID:26458562]
55. Yuhang Sun,Chuchu Xu,Changsheng Li,Cheng Xia,Chuang Xu,Ling Wu,Hongyou Zhang.  (2014-05-17)  Characterization of the serum metabolic profile of dairy cows with milk fever using 1H-NMR spectroscopy..  The Veterinary quarterly,  34  ((3)): (159-163).  [PMID:24832124]
56. Jie Mu,Stefan Rampp,Evelien Carrette,Karl Roessler,Bjoern Sommer,Friedhelm Carl Schmitt,Xavier De Tiège,Hajo Hamer,Paul Boon,Elisabeth Pauli,Ingmar Bluemcke,Dong Zhou,Michael Buchfelder,Hermann Stefan.  (2014-05-24)  Clinical relevance of source location in frontal lobe epilepsy and prediction of postoperative long-term outcome..  Seizure,  23  ((7)): (553-559).  [PMID:24854960]
57. Yuanyuan Li,Shuli Man,Jing Li,Hongyan Chai,Wei Fan,Zhen Liu,Wenyuan Gao.  (2014-07-12)  The antitumor effect of formosanin C on HepG2 cell as revealed by 1H-NMR based metabolic profiling..  Chemico-biological interactions,  220  (193-199).  [PMID:25014414]

Solution Calculators