Sodium salicylate is a metabolite of acetylsalicylic acid, and functions by inhibiting NF κ B and reduces oxidative stress. The agent has the ability to protect against neurotoxicity induced by glutamate in rat studies. Along with aspirin , sodium salicyl
Storage Temp
Protected from light
Shipped In
Normal
Grade
AR
Product Description
Sodium salicylate is the active ingredient in aspirin, commonly used as antipyretic, anti-inflammatory and analgesic drug. Sodium salicylate when taken in large quantities causes temporary hearing loss and tinnitus. Prolonged treatment with sodium salicylate reduces output from cochlea permanently, reduces compound action potential amplitude in vivo and neural degeneration in vitro.Sodium salicylate treatment in lateral amygdala alters tonography and excitability, causing hyperactivity in auditory cortex. Sodium salicylate impairs the expression of cellular-Finkel?Biskis?Jinkins murine osteogenic sarcoma virus (c-fos) and δ-FosB proteins in hippocampus region and affects spatial memory and learning. Sodium salicylate affects neurogenesis in dentate gyrus region of the brain. An NF kappa B inhibitor and reducer of oxidative stress.
Associated Targets
SLCO1B1Tchem Solute carrier organic anion transporter family member 1B1 0 Activities
H2409363
