Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | Sodium salicylate|54-21-7|Sodium 2-hydroxybenzoate|Enterosalicyl|Kerasalicyl|Salsonin|Alysine|Clin|Enterosalil|Entrosalyl|Glutosalyl|Kerosal|Magsalyl|Nadisal|Salisod|Aroall|Idocyl novum|Neo-salicyl|Benzoic acid, 2-hydroxy-, monosodium salt|Natrum salicyli |
|---|---|
| Specifications & Purity | PharmPure™, USP |
| Biochemical and Physiological Mechanisms | Sodium salicylate is a metabolite of acetylsalicylic acid, and functions by inhibiting NF κ B and reduces oxidative stress. The agent has the ability to protect against neurotoxicity induced by glutamate in rat studies. Along with aspirin , sodium salicyl |
| Shipped In | Normal |
| Grade | PharmPure™, USP |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description | An NF kappa B inhibitor and reducer of oxidative stress. |
Associated Targets
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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KDM4E Tchem Lysine-specific demethylase 4E 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Names and Identifiers
| IUPAC Name | sodium;2-hydroxybenzoate |
|---|---|
| INCHI | InChI=1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1 |
| InChi Key | ABBQHOQBGMUPJH-UHFFFAOYSA-M |
| Canonical SMILES | C1=CC=C(C(=C1)C(=O)[O-])O.[Na+] |
| Isomeric SMILES | C1=CC=C(C(=C1)C(=O)[O-])O.[Na+] |
| WGK Germany | 1 |
| RTECS | VO5075000 |
| PubChem CID | 16760658 |
| Molecular Weight | 160.1 |
| Beilstein | 3732792 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J2310047 | Certificate of Analysis | Oct 16, 2023 | S104179 |
| J2310048 | Certificate of Analysis | Oct 16, 2023 | S104179 |
| B23171119 | Certificate of Analysis | Feb 23, 2023 | S104179 |
| B23171111 | Certificate of Analysis | Feb 22, 2023 | S104179 |
| A2331460 | Certificate of Analysis | Feb 06, 2023 | S104179 |
| K2215848 | Certificate of Analysis | Nov 17, 2022 | S104179 |
| K2215847 | Certificate of Analysis | Nov 16, 2022 | S104179 |
| A2219065 | Certificate of Analysis | Jan 21, 2022 | S104179 |
| A2219060 | Certificate of Analysis | Jan 20, 2022 | S104179 |
| F2230216 | Certificate of Analysis | Jan 20, 2022 | S104179 |
Chemical and Physical Properties
| Solubility | Soluble in water (1000 g/l) at 20 °C, ethanol, and glycerol. |
|---|---|
| Sensitivity | Light sensitive. |
| Flash Point(°C) | 98.3 °C |
| Boil Point(°C) | 213 °C |
| Melt Point(°C) | >300℃ |
Safety and Hazards(GHS)
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H319:Causes serious eye irritation H302:Harmful if swallowed H361:Suspected of damaging fertility or the unborn child |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. |
| WGK Germany | 1 |
| RTECS | VO5075000 |
Related Documents
References
| 1. Pritchard R et al.. (2018) Celecoxib inhibits mitochondrial O2 consumption, promoting ROS dependent death of murine and human metastatic cancer cells via the apoptotic signalling pathway.. Biochem Pharmacol, 154 (318-334). [PMID:29800556] |