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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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S305325-100g | 100g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $9.90 | |
S305325-250g | 250g | In stock | $19.90 | |
S305325-500g | 500g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $31.90 |
Synonyms | Sodium salicylate|54-21-7|Sodium 2-hydroxybenzoate|Enterosalicyl|Kerasalicyl|Salsonin|Alysine|Clin|Enterosalil|Entrosalyl|Glutosalyl|Kerosal|Magsalyl|Nadisal|Salisod|Aroall|Idocyl novum|Neo-salicyl|Benzoic acid, 2-hydroxy-, monosodium salt|Natrum salicyli |
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Specifications & Purity | ≥99% |
Storage Temp | Room temperature |
Shipped In | Normal |
Product Description | Sodium salicylate is the active ingredient in aspirin, commonly used as antipyretic, anti-inflammatory and analgesic drug. Sodium salicylate when taken in large quantities causes temporary hearing loss and tinnitus. Prolonged treatment with sodium salicylate reduces output from cochlea permanently, reduces compound action potential amplitude in vivo and neural degeneration in vitro.Sodium salicylate treatment in lateral amygdala alters tonography and excitability, causing hyperactivity in auditory cortex. Sodium salicylate impairs the expression of cellular-Finkel?Biskis?Jinkins murine osteogenic sarcoma virus (c-fos) and δ-FosB proteins in hippocampus region and affects spatial memory and learning. Sodium salicylate affects neurogenesis in dentate gyrus region of the brain. An NF kappa B inhibitor and reducer of oxidative stress.Sodium salicylate has been used: · to induce tinnitus, hyperacusis-like behavior in rats and infused directly into amygdala to measure local field potential. · to induce and confirm tinnitus by prepulse inhibition behavior (PPI) and its inhibition on learning and memory by Morris water maze test and subsequent gene expression studies in rats. · to enhance gamma amino butyric acid (GABA)ergic inhibition and enhance auditory response in the dorsal cortex of the inferior colliculus (ICd) measured by microiontophoretic technique. |
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Pubchem Sid | 24899540 |
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IUPAC Name | sodium;2-hydroxybenzoate |
INCHI | InChI=1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1 |
InChi Key | ABBQHOQBGMUPJH-UHFFFAOYSA-M |
Canonical SMILES | C1=CC=C(C(=C1)C(=O)[O-])O.[Na+] |
Isomeric SMILES | C1=CC=C(C(=C1)C(=O)[O-])O.[Na+] |
WGK Germany | 1 |
RTECS | VO5075000 |
PubChem CID | 16760658 |
Molecular Weight | 160.1 |
Beilstein | 3732792 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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F2421364 | Certificate of Analysis | Jun 11, 2024 | S305325 |
F2421365 | Certificate of Analysis | Jun 11, 2024 | S305325 |
F2421366 | Certificate of Analysis | Jun 11, 2024 | S305325 |
F2421367 | Certificate of Analysis | Jun 11, 2024 | S305325 |
F2421387 | Certificate of Analysis | Jun 11, 2024 | S305325 |
E2407033 | Certificate of Analysis | Apr 03, 2024 | S305325 |
F2124136 | Certificate of Analysis | Apr 03, 2024 | S305325 |
A2316126 | Certificate of Analysis | Feb 01, 2023 | S305325 |
J2218335 | Certificate of Analysis | Oct 27, 2022 | S305325 |
E2230030 | Certificate of Analysis | Jun 07, 2022 | S305325 |
C2221061 | Certificate of Analysis | Jul 01, 2021 | S305325 |
E2304363 | Certificate of Analysis | Jul 01, 2021 | S305325 |
F2124134 | Certificate of Analysis | Jul 01, 2021 | S305325 |
H2304167 | Certificate of Analysis | Jul 01, 2021 | S305325 |
L2308093 | Certificate of Analysis | Jul 01, 2021 | S305325 |
Solubility | Soluble in water, 1,4-dioxane, ethanol and glycerol. |
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Sensitivity | Light sensitive |
Flash Point(°C) | 98.3 °C |
Boil Point(°C) | 213 °C |
Melt Point(°C) | >300℃ |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H302:Harmful if swallowed H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. |
WGK Germany | 1 |
RTECS | VO5075000 |
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