| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| S655728-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,099.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Sofiniclin (ABT 894), an agonist of nicotinic acetylcholine receptor (nAChR) , is used as a potential non-stimulant research for attention-deficit/hyperactivity disorder (ADHD). In Vitro Sofiniclin is more potent than ABT-089 at both receptor subtypes, with K i values of 1.9 nM for 125 I-α-conotoxinMII binding and of 1.3 nM for 125 I-epibatidine binding. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Sofiniclin (0.001 to 0.10 mg/kg, p.o.) produces significant reductions in LIDs compared to vehicle monkey . Sofiniclin (0.1 mg/kg) does not decrease LIDs in monkeys with severe nigrostriatal damage. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Canonical SMILES | ClC1=C(Cl)C=C(N2C[C@]3([H])CN[C@]3([H])C2)C=N1 |
|---|---|
| Molecular Weight | 244.12 |
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