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Spaglumic Acid - 98%, high purity , CAS No.3106-85-2, Agonist of mGlu 3 receptor
Basic Description Synonyms spaglumic acid|Isospaglumic acid|3106-85-2|NAAG|N-Acetylaspartylglutamic acid|N-Acetyl-Asp-Glu|N-acetylaspartylglutamate|N-Acetyl-L-aspartyl-L-glutamic acid|NAAGA|Isospaglumic acid [INN]|(S)-2-((S)-2-Acetamido-3-carboxypropanamido)pentanedioic acid|1W8M12 Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms The most abundant peptide neurotransmitter in the mammalian CNS. A weak activator of NMDA receptors, and a highly selective agonist for mGlu3receptors. Neuroprotective under non-hydrolysing conditionsin vivo. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of mGlu 3 receptor
Names and Identifiers IUPAC Name (2S)-2-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]pentanedioic acid INCHI InChI=1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7-/m0/s1 InChi Key OPVPGKGADVGKTG-BQBZGAKWSA-N Canonical SMILES CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O Isomeric SMILES CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O PubChem CID 188803 Molecular Weight 304.25
Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: 30.43, Max Conc. mM: 100
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
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H2316483