SPDP-PEG4-acid - 98%, high purity , CAS No.581065-97-6

  • ≥98%
Item Number
S597539
Grouped product items
SKUSizeAvailabilityPrice Qty
S597539-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,081.90
S597539-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,501.90
S597539-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,951.90

SPDP-PEG-acid

View related series
PROTAC PROTAC Linkers Thiol PEG

Basic Description

SynonymsC70516 | OPSS-PEG4-COOH | CS-0115253 | HY-141352 | SDPD-PEG4-COOH | AKOS030213532 | OPSS-PEG4-CH2CH2COOH | Opss-peg(4)-cooh | 3-[[13-Oxo-15-(2-pyridinyldithio)-3,6,9-trioxa-12-azapentadec-1-yl]oxy]propanoic acid | SPDP-PEG4-acid | DTXSID301127165 | MFCD13
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

SPDP-PEG4-acid is a PEG derivative contianing SPDP crosslinker and carboxylic acid moieties. SPDP is reactive toward amine and thiol groups and contains a cleavable disulfide bond. Its membrane permeability allows for intracellular crosslinking reactions. The terminal caboxylic acid can react with primary amines in the presence of activators such as EDC and DCC to form stable amide bonds. The hydrophilic properties of the PEG linkers increase compound solubility in aqueous media. The water solubility properties of PEG linkers is enhanced by longer PEG chains.

Names and Identifiers

IUPAC Name 3-[2-[2-[2-[2-[3-(pyridin-2-yldisulfanyl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
INCHI InChI=1S/C19H30N2O7S2/c22-17(5-16-29-30-18-3-1-2-6-21-18)20-7-9-26-11-13-28-15-14-27-12-10-25-8-4-19(23)24/h1-3,6H,4-5,7-16H2,(H,20,22)(H,23,24)
InChi Key IJDPYTZOKIVWAN-UHFFFAOYSA-N
Canonical SMILES C1=CC=NC(=C1)SSCCC(=O)NCCOCCOCCOCCOCCC(=O)O
Isomeric SMILES C1=CC=NC(=C1)SSCCC(=O)NCCOCCOCCOCCOCCC(=O)O
Alternate CAS 581065-97-6
PubChem CID 51341021
Molecular Weight 462.6

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