Spermidine

Item Number
S755738
Grouped product items
SKUSizeAvailabilityPrice Qty
S755738-1g
1g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$73.90
S755738-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$256.90

Basic Description

Specifications & PurityBioUltra, for molecular biology, ≥99.5%(GC)
Biochemical and Physiological MechanismsInhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.Spermidine modulates various cellular activities like cellular growth and develo
Storage TempRoom temperature
Shipped InNormal
GradeBioUltra, for molecular biology
Product Description

Spermidine is a polyamine and a trivalent organic cation.Spermidine is a naturally occurring polyamine compound with diverse biochemical properties. It plays a vital role in gene expression, participating in DNA replication, transcription, and translation processes. Spermidine is crucial for cell growth, proliferation, and differentiation, influencing cell cycle progression and tissue development. It possesses antioxidant activity, safeguarding cells against oxidative stress by scavenging free radicals. Spermidine also stimulates autophagy, promoting the turnover of damaged organelles and protein aggregates for cellular homeostasis. With neuroprotective effects, it supports neuronal survival, synaptic plasticity, and guards against neurodegenerative diseases. Additionally, spermidine modulates cellular signaling pathways involved in inflammation and immune responses.
Application:
Spermidine has been used:
  • as a component of chromosome isolation buffer
  • as a component of transcription buffer
  • as a component of homogenization buffer

Names and Identifiers

PH12.0-13.5 (25 °C, 1 M in H 2 O)
IUPAC Name N'-(3-aminopropyl)butane-1,4-diamine
INCHI InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
InChi Key ATHGHQPFGPMSJY-UHFFFAOYSA-N
Canonical SMILES C(CCNCCCN)CN
Isomeric SMILES C(CCNCCCN)CN
WGK Germany 3
PubChem CID 1102
UN Number 2735
Molecular Weight 145.25
Beilstein 1698591

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityH 2 O: 1 M at 20 °C, clear, colorless
Refractive Index1.4785-1.4805
Flash Point(°F)230°F
Flash Point(°C)>110°
Boil Point(°C)128-130°C
Melt Point(°C)22-25°C

Safety and Hazards(GHS)

Pictogram(s) GHS05
Signal Danger
Hazard Statements

H314:Causes severe skin burns and eye damage

H318:Causes serious eye damage

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P363:Wash contaminated clothing before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P317:Get emergency medical help.

P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes.

P316:Get emergency medical help immediately.

WGK Germany 3

Related Documents

Solution Calculators