Grouped product items

SKU

Size

Availability

Price

Qty

S141278-25ml

25ml

In stock

$15.90

S141278-100ml

100ml

In stock

$39.90

S141278-500ml

500ml

Available within 4-8 weeks(?)

$115.90

Basic Description

Synonyms	SQUALANE\|111-01-3\|2,6,10,15,19,23-Hexamethyltetracosane\|Perhydrosqualene\|Dodecahydrosqualene\|Cosbiol\|Hexamethyltetracosane\|Vitabiosol\|Spinacane\|Robane\|Tetracosane, 2,6,10,15,19,23-hexamethyl-\|Squalan\|NSC 6851\|Squalane [NF]\|squalane-d62\|Pripure 3759\|NSC-68
Specifications & Purity	≥95%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	Product Describtion: Dielectrophoretic deformation of thin liquid fillm of squalane has been investigated.Microfluidized squalenes are efficient adjuvants, eliciting both humoral and cellular immune responses. Product Application： Squalane has been used: as solvent in the synthesis of Europium dibenzoylmethide triethylammonium, brightest known triboluminescent (TL) material;as lubricant for fatty acid surfactant films adsorbed on iron oxide surfaces Squalane influence on the vital pathway that transforms glucose into cholesterol may be pivotal. It regulates or controls the rate of synthesis of the enzyme HMG Co-A reductase, and may contribute to effective treatments for cancer and heart disease. It plays an important role as a terminator in the biomembrane.

Associated Targets

LMNA Tbio Prelamin-A/C 0 Activities

Discover Target: LMNA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2,6,10,15,19,23-hexamethyltetracosane
INCHI	InChI=1S/C30H62/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h25-30H,9-24H2,1-8H3
InChi Key	PRAKJMSDJKAYCZ-UHFFFAOYSA-N
Canonical SMILES	CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C
Isomeric SMILES	CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C
WGK Germany	3
RTECS	XB6070000
PubChem CID	8089
Molecular Weight	422.81
Beilstein	776019
Reaxy-Rn	776019

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

12 results found

Lot Number	Certificate Type	Date	Item
D23061000	Certificate of Analysis	Mar 01, 2023	S141278
D23061001	Certificate of Analysis	Mar 01, 2023	S141278
D2306912	Certificate of Analysis	Mar 01, 2023	S141278
A2431214	Certificate of Analysis	Mar 01, 2023	S141278
D2304078	Certificate of Analysis	Mar 01, 2023	S141278
D2304079	Certificate of Analysis	Mar 01, 2023	S141278
D2304082	Certificate of Analysis	Mar 01, 2023	S141278
H2222160	Certificate of Analysis	Aug 15, 2022	S141278
H2222161	Certificate of Analysis	Aug 15, 2022	S141278
H2222162	Certificate of Analysis	Aug 15, 2022	S141278
C2208390	Certificate of Analysis	Feb 19, 2022	S141278
C2208466	Certificate of Analysis	Feb 19, 2022	S141278

Chemical and Physical Properties

Solubility	Soluble in ether, chloroform, benzene, slightly soluble in ethanol, acetone, methanol, insoluble in water
Refractive Index	1.45-1.452
Flash Point(°F)	424.4 °F
Flash Point(°C)	218 °C
Boil Point(°C)	350 °C
Melt Point(°C)	-38 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H413:May cause long lasting harmful effects to aquatic life
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	XB6070000
Reaxy-Rn	776019

Alternative Products

References

1. Napaporn Komesvarakul,Monica D Sanders,Erika Szekeres,Edgar J Acosta,James F Faller,Tony Mentlik,Louis B Fisher,Gregg Nicoll,David A Sabatini,John F Scamehorn. (2006-09-08) Microemulsions of triglyceride-based oils: The effect of co-oil and salinity on phase diagrams.. Journal of cosmetic science, 57 ((4)): (309-325). [PMID:16957810]
2. Alejandro F Barrero,M Mar Herrador,José F Quílez del Moral,Pilar Arteaga,Jesús F Arteaga,Horacio R Diéguez,Elena M Sánchez. (2007-03-23) Mild TiIII- and Mn/ZrIV-catalytic reductive coupling of allylic halides: efficient synthesis of symmetric terpenes.. The Journal of organic chemistry, 72 ((8)): (2988-2995). [PMID:17375959]
3. Yueying Ren,Huanxiang Liu,Xiaojun Yao,Mancang Liu. (2007-05-01) Three-dimensional topographic index applied to the prediction of acyclic C5-C8 alkenes Kováts retention indices on polydimethylsiloxane and squalane columns.. Journal of chromatography. A, 1155 ((1)): (105-111). [PMID:17466321]
4. Lok Kumar Shrestha,Rekha Goswami Shrestha,Conxita Solans,Kenji Aramaki. (2007-05-26) Effect of water on foaming properties of diglycerol fatty acid ester-oil systems.. Langmuir : the ACS journal of surfaces and colloids, 23 ((13)): (6918-6926). [PMID:17523681]
5. Aliasgar Shahiwala,Mansoor M Amiji. (2008-05-01) Enhanced mucosal and systemic immune response with squalane oil-containing multiple emulsions upon intranasal and oral administration in mice.. Journal of drug targeting, 16 ((4)): (302-310). [PMID:18446609]
6. Alexander M Zolot,Paul J Dagdigian,David J Nesbitt. (2008-11-26) Quantum-state resolved reactive scattering at the gas-liquid interface: F+squalane (C30H62) dynamics via high-resolution infrared absorption of nascent HF(v,J).. The Journal of chemical physics, 129 ((19)): (194705-194705). [PMID:19026079]
7. Mohammad Mydul Alam,Kousuke Ushiyama,Kenji Aramaki. (2009-06-06) Phase behavior, formation, and rheology of cubic phase and related gel emulsion in Tween 80/water/oil systems.. Journal of oleo science, 58 ((7)): (361-367). [PMID:19491531]
8. L Harivardhan Reddy,Jack-Michel Renoir,Veronique Marsaud,Sinda Lepetre-Mouelhi,Didier Desmaële,Patrick Couvreur. (2009-07-29) Anticancer efficacy of squalenoyl gemcitabine nanomedicine on 60 human tumor cell panel and on experimental tumor.. Molecular pharmaceutics, 6 ((5)): (1526-1535). [PMID:19634915]
9. Christopher B Fox. (2009-09-29) Squalene emulsions for parenteral vaccine and drug delivery.. Molecules (Basel, Switzerland), 14 ((9)): (3286-3312). [PMID:19783926]
10. Federica Camin,Luana Bontempo,Luca Ziller,Cristiana Piangiolino,Gianni Morchio. (2010-05-26) Stable isotope ratios of carbon and hydrogen to distinguish olive oil from shark squalene-squalane.. Rapid communications in mass spectrometry : RCM, 24 ((12)): (1810-1816). [PMID:20499327]
11. Shinya Kato,Hisae Aoshima,Yasukazu Saitoh,Nobuhiko Miwa. (2010-05-27) Defensive effects of fullerene-C60 dissolved in squalane against the 2,4-nonadienal-induced cell injury in human skin keratinocytes HaCaT and wrinkle formation in 3D-human skin tissue model.. Journal of biomedical nanotechnology, 6 ((1)): (52-58). [PMID:20499832]
12. Shinya Kato,Hikaru Taira,Hisae Aoshima,Yasukazu Saitoh,Nobuhiko Miwa. (2010-12-09) Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics.. Journal of nanoscience and nanotechnology, 10 ((10)): (6769-6774). [PMID:21137794]
13. Scott Yockel,George C Schatz. (2011-04-21) Dynamic QM/MM: a hybrid approach to simulating gas-liquid interactions.. Topics in current chemistry, 307 (43-67). [PMID:21506003]
14. Bruce A Kowert,Michael B Watson. (2011-07-26) Diffusion of organic solutes in squalane.. The journal of physical chemistry. B, 115 ((32)): (9687-9694). [PMID:21780767]
15. D Seveno,T D Blake,S Goossens,J De Coninck. (2011-11-02) Predicting the wetting dynamics of a two-liquid system.. Langmuir : the ACS journal of surfaces and colloids, 27 ((24)): (14958-14967). [PMID:22040276]
16. Mirna Peric,Barney L Bales,Miroslav Peric. (2012-02-01) Electron paramagnetic resonance line shifts and line shape changes due to heisenberg spin exchange and dipole-dipole interactions of nitroxide free radicals in liquids 8. Further experimental and theoretical efforts to separate the effects of the two interactions.. The journal of physical chemistry. A, 116 ((11)): (2855-2866). [PMID:22288424]
17. Bernard P Binks,Paul D I Fletcher,Andrew J Johnson,Russell P Elliott. (2012-10-18) How membrane permeation is affected by donor delivery solvent.. Physical chemistry chemical physics : PCCP, 14 ((44)): (15525-15538). [PMID:23073464]
18. Richard A Graves,Grace A Ledet,Cedric A Nation,Yashoda V Pramar,Levon A Bostanian,Tarun K Mandal. (2015-06-13) Effect of squalane on mebendazole-loaded Compritol® nanoparticles.. Journal of biomaterials science. Polymer edition, 26 ((13)): (868-880). [PMID:26062393]
19. K N Masihi,W Lange,M Ozel. (1988-05-25) Biomedical applications of chromatographic fraction containing trehalose dimycolate in squalane emulsion.. Journal of chromatography, 440 (473-478). [PMID:3042798]
20. Yuya Shimizu,Katsuo Karamatsu,Akihiro Matsubara,Yasuhiro Yasutomi. (2008-10-23) [Innovation of vaccine adjuvants].. Nihon rinsho. Japanese journal of clinical medicine, 66 ((10)): (1915-1921). [PMID:18939490]
21. Brian K Radak,Scott Yockel,Dongwook Kim,George C Schatz. (2009-03-28) Modeling reactive scattering of F(2P) at a liquid squalane interface: a hybrid QM/MM molecular dynamics study.. The journal of physical chemistry. A, 113 ((26)): (7218-7226). [PMID:19323516]
22. Shinya Kato,Hisae Aoshima,Yasukazu Saitoh,Nobuhiko Miwa. (2009-04-18) Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue.. Basic & clinical pharmacology & toxicology, 104 ((6)): (483-487). [PMID:19371265]
23. Daniel M Packwood,Leon F Phillips. (2010-11-03) A stochastic, local mode study of neon-liquid surface collision dynamics.. Physical chemistry chemical physics : PCCP, 13 ((2)): (762-778). [PMID:21042647]
24. Chen-Lin Liu,Jared D Smith,Dung L Che,Musahid Ahmed,Stephen R Leone,Kevin R Wilson. (2011-04-02) The direct observation of secondary radical chain chemistry in the heterogeneous reaction of chlorine atoms with submicron squalane droplets.. Physical chemistry chemical physics : PCCP, 13 ((19)): (8993-9007). [PMID:21455529]
25. Se-Kwon Kim,Fatih Karadeniz. (2012-03-01) Biological importance and applications of squalene and squalane.. Advances in food and nutrition research, 65 (223-233). [PMID:22361190]
26. Rajesh Kumar,Grace Ledet,Richard Graves,Dibyadyuti Datta,Shana Robinson,Geetha P Bansal,Tarun Mandal,Nirbhay Kumar. (2015-06-27) Potent Functional Immunogenicity of Plasmodium falciparum Transmission-Blocking Antigen (Pfs25) Delivered with Nanoemulsion and Porous Polymeric Nanoparticles.. Pharmaceutical research, 32 ((12)): (3827-3836). [PMID:26113235]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Squalane - 95%, high purity , CAS No.111-01-3