The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
SR59230A - 98%, high purity , CAS No.174689-39-5, Antagonist of β 1-adrenoceptor;Antagonist of β 2-adrenoceptor;Antagonist of β 3-adrenoceptor
β-adrenergic receptor Selective Inhibitors | Agonists | Antagonists
Basic Description Synonyms 174689-39-5|SR59230A|SR 59230A|(S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate|3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate|Z4G2GB3YHU|3-(2-ETHYLPHENOXY)-1-((1S)-1,2,3,4-TETRA-HYDR Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms SR59230A is a blood-brain barrier penetrating, potent and selective antagonist of β3-adrenergic receptor with IC50 of 40 nM, 408 nM, and 648 nM for β3, β1, and β2 receptors, respectively. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of β 1-adrenoceptor;Antagonist of β 2-adrenoceptor;Antagonist of β 3-adrenoceptor Product Description Information
SR59230A is a blood-brain barrier penetrating, potent and selective antagonist ofβ3-adrenergic receptorwith IC50 of 40 nM, 408 nM, and 648 nM for β3, β1, and β2 receptors, respectively.
Targets
β3-adrenergic receptor (Cell-free assay); β1-adrenergic receptor (Cell-free assay); β2-adrenergic receptor (Cell-free assay) 40 nM; 408 nM; 648 nM
Names and Identifiers IUPAC Name (2S)-1-(2-ethylphenoxy)-3-[[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]amino]propan-2-ol;oxalic acid INCHI InChI=1S/C21H27NO2.C2H2O4/c1-2-16-8-4-6-13-21(16)24-15-18(23)14-22-20-12-7-10-17-9-3-5-11-19(17)20;3-1(4)2(5)6/h3-6,8-9,11,13,18,20,22-23H,2,7,10,12,14-15H2,1H3;(H,3,4)(H,5,6)/t18-,20-;/m0./s1 InChi Key XTBQNQMNFXNGLR-MKSBGGEFSA-N Canonical SMILES CCC1=CC=CC=C1OCC(CNC2CCCC3=CC=CC=C23)O.C(=O)(C(=O)O)O Isomeric SMILES CCC1=CC=CC=C1OC[C@H](CN[C@H]2CCCC3=CC=CC=C23)O.C(=O)(C(=O)O)O WGK Germany 3 PubChem CID 9888075 Molecular Weight 415.48
Chemical and Physical Properties Solubility Solubility (25°C) In vitro DMSO: 83 mg/mL (199.76 mM); Ethanol: 10 mg/mL (24.06 mM); Water: Insoluble; Sensitivity Moisture sensitive
Safety and Hazards(GHS) WGK Germany 3 RIDADR NONHforallmodesoftransport
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
C23031073