SRI 31215 TFA - 98%, high purity , CAS No.1832686-44-8

Item Number

S412134

Grouped product items
SKU	Size	Availability	Price
S412134-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$43.90
S412134-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$129.90
S412134-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$206.90
S412134-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$413.90
S412134-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$619.90
S412134-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$928.90

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	SRI 31215 (TFA) is a triplex inhibitor of matriptase, hepsin and hepatocyte growth factor activator (HGFA) with IC50 of 0.69 μM, 0.65 μM, 0.3 μM, respectively. SRI 31215 blocks pro-HGF activation and thus mimics the activity of HAI-1/2.
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s of 0.69 μM, 0.65 μM, 0.3 μM.

Names and Identifiers

IUPAC Name	3-[3-[(1-benzylpiperidin-4-yl)methyl]-5-methyl-2-oxo-1,3-diazinan-1-yl]benzenecarboximidamide;2,2,2-trifluoroacetic acid
INCHI	InChI=1S/C25H33N5O.C2HF3O2/c1-19-15-29(25(31)30(16-19)23-9-5-8-22(14-23)24(26)27)18-21-10-12-28(13-11-21)17-20-6-3-2-4-7-20;3-2(4,5)1(6)7/h2-9,14,19,21H,10-13,15-18H2,1H3,(H3,26,27);(H,6,7)
InChi Key	QJFJKJLPPLYFJA-UHFFFAOYSA-N
Canonical SMILES	CC1CN(C(=O)N(C1)C2=CC=CC(=C2)C(=N)N)CC3CCN(CC3)CC4=CC=CC=C4.C(=O)(C(F)(F)F)O
Isomeric SMILES	CC1CN(C(=O)N(C1)C2=CC=CC(=C2)C(=N)N)CC3CCN(CC3)CC4=CC=CC=C4.C(=O)(C(F)(F)F)O
PubChem CID	102004307
Molecular Weight	533.59

Certificates

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12 results found

Lot Number	Certificate Type	Date	Item
H2402557	Certificate of Analysis	Apr 22, 2024	S412134
H2402597	Certificate of Analysis	Apr 22, 2024	S412134
H2402598	Certificate of Analysis	Apr 22, 2024	S412134
H2402599	Certificate of Analysis	Apr 22, 2024	S412134
H2402600	Certificate of Analysis	Apr 22, 2024	S412134
H2402601	Certificate of Analysis	Apr 22, 2024	S412134
H2402603	Certificate of Analysis	Apr 22, 2024	S412134
H2402604	Certificate of Analysis	Apr 22, 2024	S412134
H2402606	Certificate of Analysis	Apr 22, 2024	S412134
H2402630	Certificate of Analysis	Apr 22, 2024	S412134
H2402631	Certificate of Analysis	Apr 22, 2024	S412134
H2402632	Certificate of Analysis	Apr 22, 2024	S412134

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