1、Product attribute Shelf life: 36 months pH Range: 7.2 - 7.8 Preservative: CMIT/MIT Boiling point : 100℃ Appearance: colourless liquid Density (20℃) : 1.064 g/cm³ Water solubility: easily soluble Odour: odourless Heat sensitive
2、Requirements for storage rooms and vessels 1.Keep container tightly closed. 2.Keep cool. 3.Do not store together with: Oxidizing agent. 4. It is possible to transport the solution at ambient temperature, unless it does not exceed 30 °C. The transport should take less than one week.
3、Effective Components and Principle of Function It is based on aqueous buffer systems with bovine serum albumin and further protein stabilizing additives, to stabilize distinct kinds of biomolecules. Furthermore,it contains substances with strong inner molecular charge differences, suitable for small biomolecules with strong charged sections, amongst others hormones. For stabilization of proteins or other biomolecules the solution provides optimum ambient conditions regarding pH value, ionic strength, hydrophilic-hydrophobic as well as ionic interactions, needed to safe the conformation and function. 4、Biosafety information The solutions contain biocides for protection from microbiological spoilage. This mixture is not classified as hazardous in accordance with Regulation (EC) No 1272/2008; It contains reaction mass of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-one (3:1). May produce an allergic reaction.
5、Advantage 1. Stabilizer for sensitive biomolecules like proteohormones or membrane proteins
6、Instruction for usage 1. Any handling to fill in other vessels or splitting has to be done under sterile conditions. 2. Frozen solutions have to be mixed thoroughly after thawing and can be used without restriction afterwards. 3.Solutions showing turbidity should not be used. Since this might be a sign of microbial contamination. 4. Only qualified staff, who are familiar with the production of immunological tests, is permitted to handle this product. 5. The solutions contain bovine serum albumin. This may result in slight shifts of the product properties. Therefore it is recommend to check every new lot for its application in the planned test systems. A reservation of distinct lots is possible. 6. The stabilizer solution is applied undiluted. The biomolecules should be diluted stepwise in the stabilizer solution, depending on the initial concentration and the planned final concentration. Depending on the requirements of the test system concentrations between 0.5 ng/ml and more than 5 µg/ml are suitable. 7. Standard- or control solutions on the basis of this product is suitable for ELISA, micro arrays and membrane based assays. 8. To suppress undesirable effects it is possible to add e.g. HAMA binder and / or further species specific proteins to the solutions. 9. For identification purposes it is possible to add dyes. In case of a request, please contact us.
7、 Special details / Limitations 1.Freshly prepared solutions are slightly opalescent but will clear up within some months. The stabilization effect is not influenced by this process. 2.This solution stabilizes also HRP conjugates very well, but shows a strong initial suppression of signals. |