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STK16-IN-1 , CAS No.S613738, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma;Inhibitor of serine/threonine kinas

  • Moligand™
Item Number
S613738
Grouped product items
SKUSizeAvailabilityPrice Qty
S613738-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
S613738-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,001.90
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mechanistic target of rapamycin kinase Inhibitor phosphatidylinositol-4，5-bisphosphate 3-kinase catalytic subunit delta Inhibitor phosphatidylinositol-4，5-bisphosphate 3-kinase catalytic subunit gamma Inhibitor serine/threonine kinase 16 Inhibitor

Basic Description

SynonymsSTK16-IN-1|1223001-53-3|1-(4-Fluoro-3-methylphenyl)-1,7-dihydro-2H-pyrrolo[2,3-h][1,6]naphthyridin-2-one|1-(4-fluoro-3-methylphenyl)-7H-pyrrolo[2,3-h][1,6]naphthyridin-2-one|GTPL9692|SCHEMBL1368254|CHEMBL4552060|DTXSID101134342|BCP20541|YYB00153|AKOS03294
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma;Inhibitor of serine/threonine kinas

Associated Targets

STK16 Tchem Serine/threonine-protein kinase 16 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PIK3CG Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PIK3CD Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MTOR Tclin Serine/threonine-protein kinase mTOR 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 1-(4-fluoro-3-methylphenyl)-7H-pyrrolo[2,3-h][1,6]naphthyridin-2-one
INCHI InChI=1S/C17H12FN3O/c1-10-8-12(3-4-14(10)18)21-15(22)5-2-11-9-20-17-13(16(11)21)6-7-19-17/h2-9H,1H3,(H,19,20)
InChi Key WQNRDXHKVSKUPI-UHFFFAOYSA-N
Canonical SMILES Fc1ccc(cc1C)n1c(=O)ccc2c1c1cc[nH]c1nc2
Isomeric SMILES CC1=C(C=CC(=C1)N2C(=O)C=CC3=CN=C4C(=C32)C=CN4)F
PubChem CID 58525066

Certificates

Certificate of Analysis(COA)

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Related Documents

 SDS

 Specification Sheet

References

1. Liu F, Wang J, Yang X, Li B, Wu H, Qi S, Chen C, Liu X, Yu K, Wang W et al..  (2016)  Discovery of a Highly Selective STK16 Kinase Inhibitor..  ACS Chem Biol,  11  (6): (1537-43).  [PMID:27082499]

Solution Calculators

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