| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| S486261-1kit | 1kit | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,867.90 |
| Specifications & Purity | Sufficient for 100 Colorimetric tests |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Description Succinyl-CoA synthetase (SCS; succinyl-CoA ligase; succinate thiokinase; EC 6.2.1.5), also known as succinyl-CoA synthetase ligase/succinate thiokinase, is a mitochondrial enzyme. The enzyme catalyzes a substrate-level phosphorylation of GDP or ADP and thus, plays a vital role in Krebs cycle. In addition, it also catalyzes the reverse reaction to supply succinyl-CoA for heme synthesis and ketone body activation. Deficiency in SCS activity is associated with encephalomyopathy and depletion of mitochondrial DNA.Aberrations in the gene expression leads to the development of diabetes and neurodegenerative diseases. Preparation instructions Suitable for the detection of Succinly-CoA synthetase in a variety of biological samples such as cell and tissue culture supernatants and purified mitochondria. Principle The Succinyl-CoA Synthetase Activity Colorimetric Assay Kit is a simple and high throughput adaptable assay for measuring SCS activity in a variety of tissues, cells, and isolated mitochondria. SCS activity is determined by measuring a colorimetri |
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