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sufugolix , Gonadotropin-releasing hormone receptor antagonist, CAS No.308831-61-0, Gonadotropin-releasing hormone receptor antagonist

Moligand™
≥98%

CAS#: 308831-61-0
Formula: C₃₆H₃₁F₂N₅O₄S
Molecular Weight: 667.72
PubChem CID: 3038517

Item Number

S613748

Grouped product items
SKU	Size	Availability	Price
S613748-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$33.90
S613748-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$82.90
S613748-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$137.90
S613748-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$305.90

View related series

GnRH1 receptor Antagonist

Basic Description

Synonyms	Sufugolix\|308831-61-0\|TAK-013\|Sufugolix(TAK-013)\|CHEMBL22055\|56S17Z6X9M\|1-(4-(5-((Benzyl(methyl)amino)methyl)-1-(2,6-difluorobenzyl)-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-3-methoxyurea\|N-(4-(5-((benzyl(methyl)amino)methy
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Gonadotropin-releasing hormone receptor antagonist
Product Description	Sufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.1 nM.

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GNRHR Tclin Gonadotropin-releasing hormone receptor 83 Activities

Discover Target: GNRHR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
INCHI	InChI=1S/C36H31F2N5O4S/c1-41(20-23-10-5-3-6-11-23)21-28-31-33(44)43(26-12-7-4-8-13-26)36(46)42(22-27-29(37)14-9-15-30(27)38)34(31)48-32(28)24-16-18-25(19-17-24)39-35(45)40-47-2/h3-19H,20-22H2,1-2H3,(H2,39,40,45)
InChi Key	UCQSBGOFELXYIN-UHFFFAOYSA-N
Canonical SMILES	CN(CC1=CC=CC=C1)CC2=C(SC3=C2C(=O)N(C(=O)N3CC4=C(C=CC=C4F)F)C5=CC=CC=C5)C6=CC=C(C=C6)NC(=O)NOC
Isomeric SMILES	CN(CC1=CC=CC=C1)CC2=C(SC3=C2C(=O)N(C(=O)N3CC4=C(C=CC=C4F)F)C5=CC=CC=C5)C6=CC=C(C=C6)NC(=O)NOC
Alternate CAS	308831-61-0
PubChem CID	3038517
MeSH Entry Terms	5-(N-benzyl-N-methylaminomethyl)-1--(2,6-difluorobenzyl)-6-(4-(3-methoxyureido)phenyl)-3-phenylthieno(2,3-d)pyrimidine-2,4(1H,3H)-dione;TAK 013;TAK013
Molecular Weight	667.72

PubChem CID

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sufugolix , Gonadotropin-releasing hormone receptor antagonist, CAS No.308831-61-0, Gonadotropin-releasing hormone receptor antagonist

Basic Description

Product Properties

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

GNRHR Tclin Gonadotropin-releasing hormone receptor 83 Activities

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

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