The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Sulfasalazine - ≥98%, high purity , CAS No.599-79-1, Inhibitor of Proton-coupled folate transporter
Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1
Basic Description Synonyms sulfasalazine|599-79-1|Salicylazosulfapyridine|Azulfidine|Salazosulfapyridine|Sulphasalazine|Salazopyrin|Asulfidine|Benzosulfa|Salazopyridin|Accucol|Azopyrin|Sulcolon|Colo-Pleon|Salazopiridazin|Azopyrine|Reupirin|Salisulf|Salazosulfapyridin|Sulfasalazinum Specifications & Purity ≥98% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type INHIBITOR Mechanism of action Inhibitor of Proton-coupled folate transporter Product Description Sulfasalazine is a sulfa agent and a derivative of mesalazine used primarily as an anti-inflammatory agent.
Names and Identifiers Pubchem Sid 488179898 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488179898 IUPAC Name 2-hydroxy-5-[[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl]benzoic acid INCHI InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25) InChi Key NCEXYHBECQHGNR-UHFFFAOYSA-N Canonical SMILES C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O Isomeric SMILES C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N=NC3=CC(=C(C=C3)O)C(=O)O WGK Germany 2 RTECS VO6250000 PubChem CID 5339 Molecular Weight 398.39 Beilstein 356241 Reaxy-Rn 356241
Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 39.84, Max Conc. mM: 100 Sensitivity Light sensitive Melt Point(°C) 260-265°C
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Danger Hazard Statements H317: May cause an allergic skin reaction
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled
H360: May damage fertility or the unborn child
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P284: [In case of inadequate ventilation] Wear respiratory protection.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P272: Contaminated work clothing should not be allowed out of the workplace.
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash it before reuse.
P203: Obtain, read and follow all safety instructions before use.
P318: if exposed or concerned, get medical advice.
P342+P316: If experiencing respiratory symptoms: Get emergence medical help immediately.
WGK Germany 2 RTECS VO6250000 Reaxy-Rn 356241 Merck Index 8942
References 1. Mushtaq S, Sarkar R. (2020) Sulfasalazine in dermatology: A lesser explored drug with broad therapeutic potential.. Int J Womens Dermatol, 6 (3): (191-198). [PMID:32637543 ] 2. Kussmann M, Obermueller M, Spettel K, Winkler S, Aletaha D. (2021) In vitro evaluation of disease-modifying antirheumatic drugs against rheumatoid arthritis associated pathogens of the oral microflora.. RMD Open, 7 (3): (589-97). [PMID:34588273 ]
Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator
J2212309