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SKU

Size

Availability

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Qty

S105512-1g

Available within 4-8 weeks(?)

$10.90

S105512-5g

Available within 4-8 weeks(?)

$38.90

S105512-10g

10g

Available within 4-8 weeks(?)

$70.90

S105512-25g

25g

Available within 4-8 weeks(?)

$119.90

S105512-100g

100g

Available within 4-8 weeks(?)

$336.90

S105512-250g

250g

Available within 4-8 weeks(?)

$669.90

Basic Description

Synonyms	14933-08-5\|3-(dodecyldimethylammonio)propane-1-sulfonate\|Lauryl sultaine\|N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE\|Lauryl sulfobetaine\|Zwittergent 3-12\|Sulfobetaine 12\|3-(Dodecyldimethylammonio)propanesulfonate\|Sulfobetaine-12\|Dodecyldimethyl(3-
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Synthetic zwitterionic detergent, which unlike other amphoteric surfactants, retains its zwitterionic character over a broad pH range. This property is attributed to the presence of both a strongly basic quaternary ammonium ion and an acidic sulfonate ion
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate is a zwitterionic surfactant. N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate has been used in a study to assess protein structural change in a mixed system of ionic and zwitterionic surfactants. It has also been used in a study to investigate the interaction between ionic liquid and zwitterionic surfactant.

Names and Identifiers

IUPAC Name	3-[dodecyl(dimethyl)azaniumyl]propane-1-sulfonate
INCHI	InChI=1S/C17H37NO3S/c1-4-5-6-7-8-9-10-11-12-13-15-18(2,3)16-14-17-22(19,20)21/h4-17H2,1-3H3
InChi Key	IZWSFJTYBVKZNK-UHFFFAOYSA-N
Canonical SMILES	CCCCCCCCCCCC[N+](C)(C)CCCS(=O)(=O)[O-]
Isomeric SMILES	CCCCCCCCCCCC[N+](C)(C)CCCS(=O)(=O)[O-]
WGK Germany	2
PubChem CID	84703
UN Number	3261
Molecular Weight	335.55
Beilstein	4145308
Reaxy-Rn	4145308

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

15 results found

Lot Number	Certificate Type	Date	Item
H2430539	Certificate of Analysis	Aug 02, 2024	S105512
H2430552	Certificate of Analysis	Aug 02, 2024	S105512
H2430553	Certificate of Analysis	Aug 02, 2024	S105512
A2429399	Certificate of Analysis	Aug 03, 2023	S105512
H2318708	Certificate of Analysis	Aug 03, 2023	S105512
H2318709	Certificate of Analysis	Aug 03, 2023	S105512
H2318710	Certificate of Analysis	Aug 03, 2023	S105512
E1818140	Certificate of Analysis	Apr 02, 2022	S105512
D1810210	Certificate of Analysis	Feb 21, 2022	S105512
B2223450	Certificate of Analysis	Dec 17, 2021	S105512
B2223518	Certificate of Analysis	Dec 17, 2021	S105512
B2223524	Certificate of Analysis	Dec 17, 2021	S105512
B2223525	Certificate of Analysis	Dec 17, 2021	S105512
B2223528	Certificate of Analysis	Dec 17, 2021	S105512
B2324025	Certificate of Analysis	Dec 17, 2021	S105512

Chemical and Physical Properties

Solubility	Chloroform (Slightly), Methanol (Slightly)
Sensitivity	Moisture sensitive
Flash Point(°F)	110 °C
Flash Point(°C)	110°C
Melt Point(°C)	244°C(lit.)

Safety and Hazards(GHS)

Pictogram(s)	GHS09, GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H314:Causes severe skin burns and eye damage H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately.
WGK Germany	2
Reaxy-Rn	4145308

References

1. S Orlowski,M A Selosse,C Boudon,C Micoud,L M Mir,J Belehradek,M Garrigos. (1999-01-29) Effects of detergents on P-glycoprotein atpase activity: differences in perturbations of basal and verapamil-dependent activities.. Cancer biochemistry biophysics, 16 ((1-2)): (85-110). [PMID:9923970]
2. W Hu,K Tanaka,K Hasebe. (2000-06-01) Determination of inorganic anions in biological fluids with direct sample injection by electrostatic ion chromatography using zwitterionic micelles in both stationary and mobile phases.. The Analyst, 125 ((3)): (447-451). [PMID:10829344]
3. B Fricke. (2000-06-28) Quantitative determination of zwitterionic detergents using salt-induced phase separation of Triton X-100.. Analytical biochemistry, 281 ((2)): (144-150). [PMID:10870829]
4. J W Anderson,R F Pratt. (2000-10-04) Dipeptide binding to the extended active site of the Streptomyces R61 D-alanyl-D-alanine-peptidase: the path to a specific substrate.. Biochemistry, 39 ((40)): (12200-12209). [PMID:11015198]
5. H L Liou,J Storch. (2001-05-24) Role of surface lysine residues of adipocyte fatty acid-binding protein in fatty acid transfer to phospholipid vesicles.. Biochemistry, 40 ((21)): (6475-6485). [PMID:11371211]
6. U Boronowsky,S Wenk,D Schneider,C Jäger,M Rögner. (2001-06-22) Isolation of membrane protein subunits in their native state: evidence for selective binding of chlorophyll and carotenoid to the b(6) subunit of the cytochrome b(6)f complex.. Biochimica et biophysica acta, 1506 ((1)): (55-66). [PMID:11418097]
7. R R Julian,R Hodyss,J L Beauchamp. (2001-07-27) Salt bridge stabilization of charged zwitterionic arginine aggregates in the gas phase.. Journal of the American Chemical Society, 123 ((15)): (3577-3583). [PMID:11472129]
8. Paul L Sorgen,Sean M Cahill,Ray D Krueger-Koplin,Suzanne T Krueger-Koplin,Craig C Schenck,Mark E Girvin. (2002-01-05) Structure of the Rhodobacter sphaeroides light-harvesting 1 beta subunit in detergent micelles.. Biochemistry, 41 ((1)): (31-41). [PMID:11772000]
9. Marien I de Jonge,Martine P Bos,Hendrik J Hamstra,Wim Jiskoot,Peter van Ulsen,Jan Tommassen,Loek van Alphen,Peter van der Ley. (2002-10-24) Conformational analysis of opacity proteins from Neisseria meningitidis.. European journal of biochemistry, 269 ((21)): (5215-5223). [PMID:12392553]
10. Suguru Yamamoto,Kazuhiro Hasegawa,Itaru Yamaguchi,Shinobu Tsutsumi,József Kardos,Yuji Goto,Fumitake Gejyo,Hironobu Naiki. (2004-08-25) Low concentrations of sodium dodecyl sulfate induce the extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH.. Biochemistry, 43 ((34)): (11075-11082). [PMID:15323566]
11. Abhay H Pande,David Moe,Kathleen N Nemec,Shan Qin,Shuhua Tan,Suren A Tatulian. (2004-11-17) Modulation of human 5-lipoxygenase activity by membrane lipids.. Biochemistry, 43 ((46)): (14653-14666). [PMID:15544336]
12. E H Chowdhury,Toshihiro Akaike. (2005-08-13) Rapid isolation of high quality, multimeric plasmid DNA using zwitterionic detergent.. Journal of biotechnology, 119 ((4)): (343-347). [PMID:16095744]
13. Zhan-guang Chen,Xu-hong Liao,Ya-li Han,Ying-yi Yang,Feng Lu,Wei-feng Ding. (2006-01-07) [Study on BS-12 as a new probe for the determination of DNA by resonance light scattering].. Guang pu xue yu guang pu fen xi = Guang pu, 25 ((10)): (1680-1683). [PMID:16395913]
14. Hongying Jia,Gengliang Yang,Zhiwei Li,Peiyong Xin,Yu Zhao,Yi Chen. (2007-02-03) Micellar liquid chromatography with dodecyl dimethyl betaine as an in vitro method for prediction of protein-drug binding.. Journal of chromatography. A, 1143 ((1-2)): (88-97). [PMID:17266966]
15. Mónica Ferrit,Carmen del Valle,Fernando Martínez. (2007-05-15) The study of the influence of surfactant charge on alkaline hydrolysis reactions of acetylsalicylic acid (ASA) and triflusal (TFL) using spectrophotometric methods.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 31 ((3-4)): (211-220). [PMID:17498930]
16. Feng He,Sangeeta B Joshi,Fons Bosman,Marijke Verhaeghe,C Russell Middaugh. (2008-12-17) Structural stability of hepatitis C virus envelope glycoprotein E1: effect of pH and dissociative detergents.. Journal of pharmaceutical sciences, 98 ((9)): (3340-3357). [PMID:19072857]
17. Henrik Everberg,Niklas Gustavsson,Folke Tjerneld. (2009-01-21) Extraction of yeast mitochondrial membrane proteins by solubilization and detergent/polymer aqueous two-phase partitioning.. Methods in molecular biology (Clifton, N.J.), 528 (73-81). [PMID:19153685]
18. Nidhi Puri,Om Prakash,Raman Manoharlal,Monika Sharma,Indira Ghosh,Rajendra Prasad. (2010-08-27) Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.. European journal of medicinal chemistry, 45 ((11)): (4813-4826). [PMID:20739103]
19. Masahiro Yoshizawa-Fujita,Nolene Byrne,Maria Forsyth,Douglas R MacFarlane,Hiroyuki Ohno. (2010-11-23) Proton transport properties in zwitterion blends with Brønsted acids.. The journal of physical chemistry. B, 114 ((49)): (16373-16380). [PMID:21087027]
20. Lau Khye Tee,Chong Siew Ling,Ming Jang Chua,Syahril Abdullah,Rozita Rosli,Ezharul Hoque Chowdhury. (2011-03-23) Purification of transcriptionally active multimeric plasmid DNA using zwitterionic detergent and carbonate apatite nano-particles.. Plasmid, 66 ((1)): (38-46). [PMID:21419794]
21. Habauka M Kwaambwa,Adrian R Rennie. (2011-12-16) Interactions of surfactants with a water treatment protein from Moringa oleifera seeds in solution studied by zeta-potential and light scattering measurements.. Biopolymers, 97 ((4)): (209-218). [PMID:22170587]
22. Beatriz Martín-García,M Mercedes Velázquez,Francesco Rossella,Vittorio Bellani,Enrique Diez,Jose Luis García Fierro,Jose Antonio Pérez-Hernández,Juan Hernández-Toro,Sergi Claramunt,Albert Cirera. (2012-08-15) Functionalization of reduced graphite oxide sheets with a zwitterionic surfactant.. Chemphyschem : a European journal of chemical physics and physical chemistry, 13 ((16)): (3682-3690). [PMID:22890873]
23. Michaela Herrmann,Bartholomäus Danielczak,Martin Textor,Jessica Klement,Sandro Keller. (2015-05-29) Modulating bilayer mechanical properties to promote the coupled folding and insertion of an integral membrane protein.. European biophysics journal : EBJ, 44 ((7)): (503-512). [PMID:26016666]
24. Georgia L Isom,Nicolas Coudray,Mark R MacRae,Collin T McManus,Damian C Ekiert,Gira Bhabha. (2020-05-04) LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.. Cell, 181 ((3)): (653-664). [PMID:32359438]
25. D Boehning,S K Joseph. (2000-10-18) Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptors.. The EMBO journal, 19 ((20)): (5450-5459). [PMID:11032812]
26. Cecile Ancey,Emmanuelle Menet,Pierre Corbi,Sandra Fredj,Martine Garcia,Catherine Rücker-Martin,Jocelyn Bescond,Franck Morel,John Wijdenes,Jean-Claude Lecron,Daniel Potreau. (2003-06-28) Human cardiomyocyte hypertrophy induced in vitro by gp130 stimulation.. Cardiovascular research, 59 ((1)): (78-85). [PMID:12829178]
27. María Muñoz,Amalia Rodríguez,María Del Mar Graciani,María Luisa Moyá. (2004-12-01) Conductometric, surface tension, and kinetic studies in mixed SDS-Tween 20 and SDS-SB3-12 micellar solutions.. Langmuir : the ACS journal of surfaces and colloids, 20 ((25)): (10858-10867). [PMID:15568834]

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Sulfobetaine 12 - 98%, high purity , CAS No.14933-08-5

Basic Description

Names and Identifiers

Certificates

Certificate of Analysis(COA)

more

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

References

Solution Calculators

Molarity Calculator

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SKU	Size	Availability	Price
S105512-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$10.90
S105512-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$38.90
S105512-10g	10g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$70.90
S105512-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$119.90
S105512-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$336.90
S105512-250g	250g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$669.90