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SUVN-911 , CAS No.S614269, Antagonist of nicotinic acetylcholine receptor α4 subunit

SUVN-911 , CAS No.S614269, Antagonist of nicotinic acetylcholine receptor α4 subunit

Item Number

S614269

Grouped product items
SKU	Size	Availability	Price	Qty
S614269-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$275.90
S614269-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$825.90

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Basic Description

Synonyms	compound 9h
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of nicotinic acetylcholine receptor α4 subunit

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	3-[(6-chloropyridin-3-yl)oxymethyl]-2-azabicyclo[3.1.0]hexane
INCHI	InChI=1S/C11H13ClN2O/c12-11-2-1-9(5-13-11)15-6-8-3-7-4-10(7)14-8/h1-2,5,7-8,10,14H,3-4,6H2
InChi Key	PYSCVJMLJRHJGJ-UHFFFAOYSA-N
Canonical SMILES	Clc1ccc(cn1)OCC1CC2C(N1)C2
Isomeric SMILES	C1C2CC2NC1COC3=CN=C(C=C3)Cl
PubChem CID	53236401

PubChem CID	53236401

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1. Nirogi R, Mohammed AR, Shinde AK, Ravella SR, Bogaraju N, Subramanian R, Mekala VR, Palacharla RC, Muddana N, Thentu JB et al.. (2020) Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.. J Med Chem, 63 (6): (2833-2853). [PMID:32026697]

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