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Swertiajaponin - ≥99.0%, high purity , CAS No.6980-25-2

  • ≥99%
Item Number
S647221
Grouped product items
SKUSizeAvailabilityPrice Qty
S647221-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$229.90
S647221-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$686.90

Flavonoids Flavones Phenols Polyphenols

Basic Description

SynonymsSwertiajaponin|6980-25-2|Leucanthoside|C10187|4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-|2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran
Specifications & Purity≥99%
Biochemical and Physiological MechanismsSwertiajaponin is a tyrosinase inhibitor , forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase , with an IC 50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

Swertiajaponin is a tyrosinase inhibitor , forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase , with an IC 50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity

Form:Solid

IC50& Target:IC50: 43.47 μM (tyrosinase)

Associated Targets

XDH Tclin Xanthine dehydrogenase/oxidase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
INCHI InChI=1S/C22H22O11/c1-31-13-6-14-16(11(26)5-12(32-14)8-2-3-9(24)10(25)4-8)19(28)17(13)22-21(30)20(29)18(27)15(7-23)33-22/h2-6,15,18,20-25,27-30H,7H2,1H3/t15-,18-,20+,21-,22+/m1/s1
InChi Key DLVLXOYLQKCAME-DGHBBABESA-N
Canonical SMILES COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O)C4C(C(C(C(O4)CO)O)O)O
Isomeric SMILES COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O
Alternate CAS 6980-25-2
PubChem CID 442659
MeSH Entry Terms swertiajaponin
Molecular Weight 462.40

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