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TAPS - 99%, high purity , CAS No.29915-38-6

  • ≥99%
Item Number
T108961
Grouped product items
SKUSizeAvailabilityPrice Qty
T108961-5g
5g
3
$9.90
T108961-25g
25g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$25.90
T108961-100g
100g
3
$80.90
T108961-500g
500g
3
$360.90

Basic Description

Synonyms3-((2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino)-1-propanesulfonic acid | 3-(Tris(hydroxymethyl)methylamino)-1-propanesulfonic acid | CHEBI:191055 | Thiosemicarbazone | 1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- | DTXSID3067
Specifications & Purity≥99%
Storage TempRoom temperature
Shipped InNormal
Product Description

TAPS is a zwitterionic buffer used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. TAPS has been utilized in capillary electrophoresis of DNA and DNA-dye complexes. Dyes can be separated by planar chromatography with electroosmotic flow containing 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated through the use of capillary electrophoresis. TAPS has also been shown to inhibit the activity of connexin channels. The activity of various carbonic anhydrases has been studied using TAPS physiological buffer, pKa = 8.4 at 20° C.

AI Insight

Names and Identifiers

IUPAC Name 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid
INCHI InChI=1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14)
InChi Key YNLCVAQJIKOXER-UHFFFAOYSA-N
Canonical SMILES C(CNC(CO)(CO)CO)CS(=O)(=O)O
Isomeric SMILES C(CNC(CO)(CO)CO)CS(=O)(=O)O
WGK Germany 3
PubChem CID 121591
Molecular Weight 243.28
Beilstein 2452420
Reaxy-Rn 2452420

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot NumberCertificate TypeDateItem
F2116225Certificate of AnalysisMar 04, 2025 T108961
F2116378Certificate of AnalysisMar 04, 2025 T108961
F2116379Certificate of AnalysisMar 04, 2025 T108961
L2424586Certificate of AnalysisJun 18, 2024 T108961
I2220589Certificate of AnalysisSep 23, 2022 T108961
I2220602Certificate of AnalysisSep 23, 2022 T108961
I2403039Certificate of AnalysisSep 23, 2022 T108961

Chemical and Physical Properties

Flash Point(°F)>230 ℉
Flash Point(°C)>110°C
Melt Point(°C)230-235°C
Molecular Weight243.280 g/mol
XLogP3-5.400
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Exact Mass243.078 Da
Monoisotopic Mass243.078 Da
Topological Polar Surface Area135.000 Ų
Heavy Atom Count15
Formal Charge0
Complexity247.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1

Safety and Hazards(GHS)

WGK Germany 3
Reaxy-Rn 2452420

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Citations of This Product(3)

1. Yuting Li, Luhan Wang, Minhua Qian, Shengda Qi, Lei Zhou, Qiaosheng Pu.  (2022)  Concise analysis of γ-hydroxybutyric acid in beverages and urine by capillary electrophoresis with capacitively coupled contactless conductivity detection using 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid as background electrolyte.  JOURNAL OF CHROMATOGRAPHY A,  1675  (463191).  [PMID:35675730] [10.1016/j.chroma.2022.463191]
2. Liye Yang, Guangchao Pan, Piwang Zhang, Qiang Liu, Xing Liu, Yan Li, Ying Liang, Min Zhang.  (2021)  3D printed two-in-one on-capillary detector: Combining contactless conductometric and photometric detection for capillary electrophoresis.  ANALYTICA CHIMICA ACTA,  1159  (338427).  [PMID:33867034] [10.1016/j.aca.2021.338427]
3. Wang Chen, Wang Qian, Li Shuangsi, Zhang Man, Zhao Weifeng, Sun Shudong, Zhao Changsheng.  (2017)  One-pot synthesis of highly hemocompatible polyurethane/polyethersulfone composite membranes.  POLYMER BULLETIN,  74  (9): (3797-3818).  [PMID:] [10.1007/s00289-017-1922-5]

References

1. Z Zeng,S M Clark,R A Mathies,A N Glazer.  (1997-11-05)  Improved stability and electrophoretic properties of preformed fluorescent cationic dye-DNA complexes in a taps-tetrapentylammonium buffer in agarose slab gels..  Analytical biochemistry,  252  ((1)): (110-114).  [PMID:9324948]
2. D Liang,L Song,M A Quesada,Z Tian,F W Studier,B Chu.  (2001-03-29)  Formation of concentration gradient and its application to DNA capillary electrophoresis..  Electrophoresis,  21  ((17)): (3600-3608).  [PMID:11271477]
3. Seung-ick Oh,Hang-soo Park,Insik Hwang,Han-kyul Park,Kyung-Ah Choi,Hyesun Jeong,Suhng Wook Kim,Sunghoi Hong.  (2014-07-06)  Efficient reprogramming of mouse fibroblasts to neuronal cells including dopaminergic neurons..  TheScientificWorldJournal,  2014  (957548-957548).  [PMID:24991651]
4. Patrick Kwan,Chelsea L McIntosh,David P Jennings,R Chris Hopkins,Sanjeev K Chandrayan,Chang-Hao Wu,Michael W W Adams,Anne K Jones.  (2015-10-06)  The [NiFe]-Hydrogenase of Pyrococcus furiosus Exhibits a New Type of Oxygen Tolerance..  Journal of the American Chemical Society,  137  ((42)): (13556-13565).  [PMID:26436715]
5. Myra Noemi Chávez,Thilo Ludwig Schenck,Ursula Hopfner,Carolina Centeno-Cerdas,Ian Somlai-Schweiger,Christian Schwarz,Hans-Günther Machens,Mathias Heikenwalder,María Rosa Bono,Miguel L Allende,Jörg Nickelsen,José Tomás Egaña.  (2015-10-17)  Towards autotrophic tissue engineering: Photosynthetic gene therapy for regeneration..  Biomaterials,  75  (25-36).  [PMID:26474040]
6. John-Paul Bacik,Justin R Klesmith,Timothy A Whitehead,Laura R Jarboe,Clifford J Unkefer,Brian L Mark,Ryszard Michalczyk.  (2015-09-12)  Producing glucose 6-phosphate from cellulosic biomass: structural insights into levoglucosan bioconversion..  The Journal of biological chemistry,  290  ((44)): (26638-26648).  [PMID:26354439]
7. Yuting Li, Luhan Wang, Minhua Qian, Shengda Qi, Lei Zhou, Qiaosheng Pu.  (2022)  Concise analysis of γ-hydroxybutyric acid in beverages and urine by capillary electrophoresis with capacitively coupled contactless conductivity detection using 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid as background electrolyte.  JOURNAL OF CHROMATOGRAPHY A,  1675  (463191).  [PMID:35675730] [10.1016/j.chroma.2022.463191]
8. Liye Yang, Guangchao Pan, Piwang Zhang, Qiang Liu, Xing Liu, Yan Li, Ying Liang, Min Zhang.  (2021)  3D printed two-in-one on-capillary detector: Combining contactless conductometric and photometric detection for capillary electrophoresis.  ANALYTICA CHIMICA ACTA,  1159  (338427).  [PMID:33867034] [10.1016/j.aca.2021.338427]
9. Wang Chen, Wang Qian, Li Shuangsi, Zhang Man, Zhao Weifeng, Sun Shudong, Zhao Changsheng.  (2017)  One-pot synthesis of highly hemocompatible polyurethane/polyethersulfone composite membranes.  POLYMER BULLETIN,  74  (9): (3797-3818).  [PMID:] [10.1007/s00289-017-1922-5]

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