Basic Description

Synonyms	POE (6) sorbitol monolaurate \| Tween(R) 20 \| 2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate \| SCHEMBL118527 \| Tween 40 (TN) \| 1052273-76-3 \| 2-(2-(3,4-bis(2-hydroxyethoxy)tetrahydrofuran-2-yl)-2-(2-hydroxyethoxy)eth
Specifications & Purity	for molecular biology, viscous liquids
Legal Information	TWEEN is a registered trademark of Croda International PLC
Grade	for molecular biology
Note	注意: TWEEN 20在高压灭菌下可能会不稳定，特别是在含有金属阳离子的缓冲溶液中。不推荐在没有进行属性改变测试的情况下进行高压灭菌。TWEEN 20对热较为敏感并在暴露于升高的温度下时会变暗。据报道，聚山梨醇酯与碱、重金属盐、酚和单宁酸不相容。它们还可能会降低多种保存剂的活性。聚山梨醇酯的水溶液在储存期间会经历自动氧化，以及由光、温度升高和硫酸铜所催化带来的改变。
Product Description	ECO TWEEN® 20, also known as Polyoxyethylenesorbitan monolaurate, is a bio-based, nonionic detergent manufactured from a natural fatty acid. This surfactant, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting. Its versatility makes it well-suited for a variety of applications in biochemical and biological research, with common uses including cell lysis, protein extraction, nuclei isolation and cell fractionation. We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation". TWEEN 20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family. It is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid. The ethylene oxide subunits are responsible for the hydrophilic nature of the surfactant, while the hydrocarbon chains provide the hydrophobic environment. Sorbitol forms the backbone ring to which the ethylene oxide polymers are attached.

Associated Targets(non-human)

Mus musculus (284745 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
INCHI	InChI=1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
InChi Key	HMFKFHLTUCJZJO-UHFFFAOYSA-N
Canonical SMILES	CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO
Isomeric SMILES	CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO
WGK Germany	1
RTECS	TR7400000
PubChem CID	443314

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
C2425038	Certificate of Analysis	Mar 29, 2024	T434505
F23161117	Certificate of Analysis	Jun 20, 2023	T434505
F23161120	Certificate of Analysis	Jun 20, 2023	T434505
C2310592	Certificate of Analysis	Mar 23, 2023	T434505
C2310605	Certificate of Analysis	Mar 23, 2023	T434505

Chemical and Physical Properties

Refractive Index	1.4685-1.4715
Flash Point(°C)	>149℃
Boil Point(°C)	100°C
Melt Point(°C)	-14 °C

Safety and Hazards(GHS)

WGK Germany	1
RTECS	TR7400000

FAQs and Articles

Citations of This Product

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68. Lina Wu, Xinjie Wang, Xiangchuan Wu, Shiqi Xu, Ming Liu, Xizhong Cao, Taishan Tang, Xingxu Huang, He Huang. (2022) MnO2 Nanozyme-Mediated CRISPR-Cas12a System for the Detection of SARS-CoV-2. ACS Applied Materials & Interfaces, 14 (45): (50534–50542). [PMID:36301087]
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TWEEN® 20 - Suitable for molecular biology, viscous liquids, high purity , CAS No.9005-64-5