Purity≥95% (SDS-PAGE&SEC); Endotoxin Level ≤ 0.01EU/μg ; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab183432-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $109.90 | |
| Ab183432-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $519.90 | |
| Ab183432-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,299.90 | |
| Ab183432-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,079.90 |
Purity≥95% (SDS-PAGE&SEC); Endotoxin Level ≤ 0.01EU/μg ; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Tadocizumab (anti-Integrin α2β3) - Primary antibody, specific to ITGA2; ITGB3, Human IgG1 |
|---|---|
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot |
| Specificity | ITGA2; ITGB3 |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | ANTAGONIST |
| Mechanism of action | ANTAGONIST of Integrin alpha-IIb/beta-3 antagonist |
| Product Description | Tadocizumab (anti-Integrin α2β3) is a humanized monoclonal antibody tageting integrin αIIbβ3. Tadocizumab (anti-Integrin α2β3) has antiplatelet and antithrombotic effects, and can be used for cardiovascular disease research. Purity≥95% (SDS-PAGE&SEC) Endotoxin Level ≤ 0.01EU/μg |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.3 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 339086-80-5 |
Tadocizumab (anti-Integrin α2β3) (Ab183432) - Flow Cytometry
Flow Cytometry analysis of U-2 OS cells labelling Integrin α2β3 (red) with Tadocizumab (anti-Integrin α2β3) (Ab183432). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Tadocizumab (anti-Integrin α2β3) (Ab183432) - ELISA
Immobilized Recombinant Human Integrin alpha 2b beta 3(ITGAIIb&ITGB3) Heterodimer protein, His Tag Free at 2.0 μg/mL can bind Tadocizumab (anti-Integrin α2β3) (Ab183432) with the EC
₅₀
of 4.164 ng/mL.
Tadocizumab (anti-Integrin α2β3) (Ab183432) - SEC
The purity of Tadocizumab (anti-Integrin α2β3) (Ab183432) is more than 95% verified by HPLC.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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