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TAK-653 - ≥98%, high purity , Glutamate receptor ionotropic AMPA positive allosteric modulator, CAS No.1358751-06-0, Glutamate receptor ionotropic AMPA positive allosteric modulator

  • ≥98%
Item Number
T648005
Grouped product items
SKUSizeAvailabilityPrice Qty
T648005-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$38.90
T648005-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$92.90
T648005-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$147.90
T648005-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$297.90
T648005-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$472.90
T648005-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$686.90

Basic Description

Specifications & Purity≥98%
Storage TempProtected from light,Store at -20°C,Desiccated
Shipped InIce chest + Ice pads
Action TypePOSITIVE ALLOSTERIC MODULATOR
Mechanism of actionGlutamate receptor ionotropic AMPA positive allosteric modulator
Product Description

Osavampator (TAK-653) is a AMPA receptor positive allosteric modulator. Osavampator selectively binds to AMPA-R in a glutamate-dependent manner and induces Ca2+ influx in hGluA1i CHO cells (EC50 = 3.3 μM). Osavampator improves learning and memory in many models.

Product Properties

ALogP2.7

Names and Identifiers

IUPAC Name 9-(4-cyclohexyloxyphenyl)-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide
INCHI InChI=1S/C19H23N3O3S/c1-14-13-22-11-12-26(23,24)21-19(22)18(20-14)15-7-9-17(10-8-15)25-16-5-3-2-4-6-16/h7-10,13,16H,2-6,11-12H2,1H3
InChi Key PXJBHEHFVQVDDS-UHFFFAOYSA-N
Canonical SMILES CC1=CN2CCS(=O)(=O)N=C2C(=N1)C3=CC=C(C=C3)OC4CCCCC4
Isomeric SMILES CC1=CN2CCS(=O)(=O)N=C2C(=N1)C3=CC=C(C=C3)OC4CCCCC4
PubChem CID 56655833
Molecular Weight 373.47

Certificates

Certificate of Analysis(COA)

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6 results found

Lot NumberCertificate TypeDateItem
H2415427Certificate of AnalysisMay 06, 2024 T648005
H2415428Certificate of AnalysisMay 06, 2024 T648005
H2415429Certificate of AnalysisMay 06, 2024 T648005
H2415430Certificate of AnalysisMay 06, 2024 T648005
H2415431Certificate of AnalysisMay 06, 2024 T648005
H2415432Certificate of AnalysisMay 06, 2024 T648005

Chemical and Physical Properties

SolubilityDMSO : ≥ 12.5 mg/mL (33.47 mM)
Sensitivitylight & Moisture sensitive

Related Documents

Solution Calculators