| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| T655332-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $450.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | TAK1/MAP4K2 inhibitor 1 is a potent dual TGFβ-activated kinase 1 ( TAK1 ) and mitogen-activated protein kinase kinase kinase kinase 2 ( MAP4K2 ) inhibitor, with IC 50 s of 41.1 nM and 18.2 nM, respectively. In Vivo TAK1/MAP4K2 inhibitor 1 has moderate terminal elimination half-life (t 1/2 =2.94 h for mice (1 mg/kg, iv)) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:TAK1 41.1 nM (IC 50 ) MAP4K2 18.2 nM (IC 50 ) |
| Canonical SMILES | CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=C4C=C(N5)C)C(F)(F)F |
|---|---|
| Molecular Weight | 552.59 |
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