TAPS - ≥99.5%(T), high purity , CAS No.29915-38-6

1 Citations
  • ≥99.5%(T)
Item Number
T108962
Grouped product items
SKUSizeAvailabilityPrice Qty
T108962-25g
25g
In stock
$30.90
T108962-100g
100g
In stock
$87.90
T108962-500g
500g
In stock
$379.90
View related series
Biological buffer

Basic Description

SynonymsTAPS | 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid | 3-((1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)propane-1-sulfonic acid | N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic Acid | N-Tris(hydroxymethyl)methyl-3-am
Specifications & Purity≥99.5%(T)
Storage TempRoom temperature
Shipped InNormal
Product Description

TAPS is a zwitterionic buffer used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. TAPS has been utilized in capillary electrophoresis of DNA and DNA-dye complexes. Dyes can be separated by planar chromatography with electroosmotic flow containing 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated through the use of capillary electrophoresis. TAPS has also been shown to inhibit the activity of connexin channels. The activity of various carbonic anhydrases has been studied using TAPS physiological buffer, pKa = 8.4 at 20° C.

Names and Identifiers

Pubchem Sid488187651
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488187651
IUPAC Name 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid
INCHI InChI=1S/C7H17NO6S/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14/h8-11H,1-6H2,(H,12,13,14)
InChi Key YNLCVAQJIKOXER-UHFFFAOYSA-N
Canonical SMILES C(CNC(CO)(CO)CO)CS(=O)(=O)O
Isomeric SMILES C(CNC(CO)(CO)CO)CS(=O)(=O)O
WGK Germany 3
PubChem CID 121591
Molecular Weight 243.28
Beilstein 2452420
Reaxy-Rn 2452420

Certificates

Certificate of Analysis(COA)

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Lot NumberCertificate TypeDateItem
F2411466Certificate of AnalysisMay 16, 2024 T108962
F2411465Certificate of AnalysisMay 16, 2024 T108962
F2411464Certificate of AnalysisMay 16, 2024 T108962
C2427143Certificate of AnalysisMar 16, 2024 T108962
C2427144Certificate of AnalysisMar 16, 2024 T108962
C2405696Certificate of AnalysisFeb 20, 2024 T108962
B2418003Certificate of AnalysisFeb 06, 2024 T108962
B2418004Certificate of AnalysisFeb 06, 2024 T108962
B2423205Certificate of AnalysisFeb 04, 2024 T108962
I2311665Certificate of AnalysisSep 05, 2023 T108962
I2311660Certificate of AnalysisSep 05, 2023 T108962
A2409009Certificate of AnalysisApr 21, 2023 T108962
F2314318Certificate of AnalysisApr 21, 2023 T108962
F2314310Certificate of AnalysisApr 21, 2023 T108962
A1914083Certificate of AnalysisNov 17, 2022 T108962
A2409008Certificate of AnalysisOct 22, 2022 T108962
B2324872Certificate of AnalysisOct 22, 2022 T108962
B2324846Certificate of AnalysisOct 22, 2022 T108962
B2324828Certificate of AnalysisOct 22, 2022 T108962
B2324805Certificate of AnalysisOct 22, 2022 T108962
A2410420Certificate of AnalysisJul 23, 2022 T108962
I2220605Certificate of AnalysisJul 23, 2022 T108962
I2220604Certificate of AnalysisJul 23, 2022 T108962
I2220603Certificate of AnalysisJul 23, 2022 T108962
F2205119Certificate of AnalysisMay 18, 2022 T108962
D2212007Certificate of AnalysisMar 26, 2022 T108962
D2212005Certificate of AnalysisMar 26, 2022 T108962
D2212021Certificate of AnalysisMar 26, 2022 T108962
D2212022Certificate of AnalysisMar 26, 2022 T108962
F2205121Certificate of AnalysisMar 26, 2022 T108962
F2205118Certificate of AnalysisMar 26, 2022 T108962
A2410419Certificate of AnalysisMar 26, 2022 T108962
G2218048Certificate of AnalysisSep 07, 2021 T108962

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Chemical and Physical Properties

Solubilitywater: 0.5 g/mL, clear, colorless
Flash Point(°F)>230 ℉
Flash Point(°C)>110°C
Melt Point(°C)230-235°C

Safety and Hazards(GHS)

WGK Germany 3
Reaxy-Rn 2452420

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FAQs and Articles

Citations of This Product

1. Yuting Li, Luhan Wang, Minhua Qian, Shengda Qi, Lei Zhou, Qiaosheng Pu.  (2022)  Concise analysis of γ-hydroxybutyric acid in beverages and urine by capillary electrophoresis with capacitively coupled contactless conductivity detection using 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid as background electrolyte.  JOURNAL OF CHROMATOGRAPHY A,  1675  (463191).  [PMID:35675730]
2. Liye Yang, Guangchao Pan, Piwang Zhang, Qiang Liu, Xing Liu, Yan Li, Ying Liang, Min Zhang.  (2021)  3D printed two-in-one on-capillary detector: Combining contactless conductometric and photometric detection for capillary electrophoresis.  ANALYTICA CHIMICA ACTA,  1159  (338427).  [PMID:33867034]

References

1. Z Zeng,S M Clark,R A Mathies,A N Glazer.  (1997-11-05)  Improved stability and electrophoretic properties of preformed fluorescent cationic dye-DNA complexes in a taps-tetrapentylammonium buffer in agarose slab gels..  Analytical biochemistry,  252  ((1)): (110-114).  [PMID:9324948]
2. D Liang,L Song,M A Quesada,Z Tian,F W Studier,B Chu.  (2001-03-29)  Formation of concentration gradient and its application to DNA capillary electrophoresis..  Electrophoresis,  21  ((17)): (3600-3608).  [PMID:11271477]
3. Seung-ick Oh,Hang-soo Park,Insik Hwang,Han-kyul Park,Kyung-Ah Choi,Hyesun Jeong,Suhng Wook Kim,Sunghoi Hong.  (2014-07-06)  Efficient reprogramming of mouse fibroblasts to neuronal cells including dopaminergic neurons..  TheScientificWorldJournal,  2014  (957548-957548).  [PMID:24991651]
4. Patrick Kwan,Chelsea L McIntosh,David P Jennings,R Chris Hopkins,Sanjeev K Chandrayan,Chang-Hao Wu,Michael W W Adams,Anne K Jones.  (2015-10-06)  The [NiFe]-Hydrogenase of Pyrococcus furiosus Exhibits a New Type of Oxygen Tolerance..  Journal of the American Chemical Society,  137  ((42)): (13556-13565).  [PMID:26436715]
5. Myra Noemi Chávez,Thilo Ludwig Schenck,Ursula Hopfner,Carolina Centeno-Cerdas,Ian Somlai-Schweiger,Christian Schwarz,Hans-Günther Machens,Mathias Heikenwalder,María Rosa Bono,Miguel L Allende,Jörg Nickelsen,José Tomás Egaña.  (2015-10-17)  Towards autotrophic tissue engineering: Photosynthetic gene therapy for regeneration..  Biomaterials,  75  (25-36).  [PMID:26474040]
6. John-Paul Bacik,Justin R Klesmith,Timothy A Whitehead,Laura R Jarboe,Clifford J Unkefer,Brian L Mark,Ryszard Michalczyk.  (2015-09-12)  Producing glucose 6-phosphate from cellulosic biomass: structural insights into levoglucosan bioconversion..  The Journal of biological chemistry,  290  ((44)): (26638-26648).  [PMID:26354439]
7. Qianhao Wang,Haiqing Xiong,Shanshan Ai,Xianhong Yu,Yaxi Liu,Jiejie Zhang,Aibin He.  (2019-09-01)  CoBATCH for High-Throughput Single-Cell Epigenomic Profiling..  Molecular cell,  76  ((1)): (206-216).  [PMID:31471188]
8. Yuting Li, Luhan Wang, Minhua Qian, Shengda Qi, Lei Zhou, Qiaosheng Pu.  (2022)  Concise analysis of γ-hydroxybutyric acid in beverages and urine by capillary electrophoresis with capacitively coupled contactless conductivity detection using 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid as background electrolyte.  JOURNAL OF CHROMATOGRAPHY A,  1675  (463191).  [PMID:35675730]
9. Liye Yang, Guangchao Pan, Piwang Zhang, Qiang Liu, Xing Liu, Yan Li, Ying Liang, Min Zhang.  (2021)  3D printed two-in-one on-capillary detector: Combining contactless conductometric and photometric detection for capillary electrophoresis.  ANALYTICA CHIMICA ACTA,  1159  (338427).  [PMID:33867034]

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