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PGPEP1

DescriptionPyroglutamyl-peptidase 1

Gene and Protein Information

Gene ID54858
Uniprot Accession IDs A8K1Q3 Q8IVT1
Ensembl ID ENSP00000269919
Symbol PGPI PGI PGP Pcp PGPI PAP-I PGP-I
FamilyBelongs to the peptidase C15 family.
Sequence
MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQLVVHVGVSGMATTVTLEKCGHNKGYKGLDNCRFCPGSQCCVEDGPESIDSIIDMDAVCKRVTTLGLDVSVTISQDAGRYLCDFTYYTSLYQSHGRSAFVHVPPLGKPYNADQLGRALRAIIEEMLDLLEQSEGKINYCHKH
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp748692PGPEP1pyroglutamyl-peptidase I9598VGNC:14751OMA, EggNOG
Macaque720200PGPEP1pyroglutamyl-peptidase I9544Inparanoid, OMA, EggNOG
Mouse66522Pgpep1pyroglutamyl-peptidase I10090MGI:1913772Inparanoid, OMA, EggNOG
Rat290648Pgpep1pyroglutamyl-peptidase I10116RGD:1303133Inparanoid, OMA, EggNOG
Dog484823PGPEP1pyroglutamyl-peptidase I9615VGNC:44467Inparanoid, OMA, EggNOG
Horse100070946PGPEP1pyroglutamyl-peptidase I9796VGNC:21362Inparanoid, OMA, EggNOG
Cow615089PGPEP1pyroglutamyl-peptidase I9913VGNC:32799Inparanoid, OMA, EggNOG
Opossum100618797PGPEP1pyroglutamyl-peptidase I13616Inparanoid, OMA, EggNOG
Chicken420127PGPEP1pyroglutamyl-peptidase I9031CGNC:17204Inparanoid, OMA
Xenopus448426pgpep1pyroglutamyl-peptidase I8364XB-GENE-961493Inparanoid, OMA, EggNOG
Zebrafish553547pgpep1pyroglutamyl-peptidase I7955ZDB-GENE-050522-88Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    cysteine protease    /    Pyroglutamyl-peptidase 1
protein    /    protease    /    Pyroglutamyl-peptidase 1
protein    /    hydrolase    /    Pyroglutamyl-peptidase 1
DTO Classes
protein    /    Enzyme    /    Protease    /    Cysteine protease    /    Pyroglutamyl-peptidase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details
Recombinant Human PGPEP-1 ProteinE. coliC-His
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Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Diseases

NameDirect Associated TargetsDisease TypeMondoid
Astrocytoma, Pilocytic3186Expression AtlasMONDO:0016691
glioblastoma5998Expression AtlasMONDO:0018177
osteosarcoma7970Expression AtlasMONDO:0009807
psoriasis6696Expression AtlasMONDO:0005083
subependymal giant cell astrocytoma2343Expression AtlasMONDO:0016693
Hypertension0JensenLab Experiment TIGA
Hypothyroidism0JensenLab Experiment TIGA
Breast carcinoma0JensenLab Experiment TIGA
Autoimmune thyroiditis0JensenLab Experiment TIGA
Gastroesophageal reflux disease0JensenLab Experiment TIGA