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PDGFRA
Description | Platelet-derived growth factor receptor alpha |
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Gene and Protein Information
Gene ID | 5156 |
Uniprot Accession IDs | B2RE69 E9PBH0 Q6P4H5 Q96KZ7 Q9UD28 PDGF-R-alpha |
Ensembl ID | ENSP00000257290 |
Symbol | PDGFR2 RHEPDGFRA CD140A PDGFR2 PDGFR-2 |
Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. |
Sequence | MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVKEMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL Show more |
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Homologous gene and protein info.
Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
Chimp | 461318 | PDGFRA | platelet derived growth factor receptor alpha | 9598 | | OMA, EggNOG |
Macaque | | PDGFRA | platelet derived growth factor receptor alpha [Source:HGNC Symbol;Acc:HGNC:8803] | 9544 | | Inparanoid, EggNOG |
Mouse | 18595 | Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 10090 | MGI:97530 | Inparanoid, OMA, EggNOG |
Rat | 25267 | Pdgfra | platelet derived growth factor receptor alpha | 10116 | RGD:3284 | Inparanoid, OMA, EggNOG |
Dog | 442860 | PDGFRA | platelet derived growth factor receptor alpha | 9615 | VGNC:44372 | Inparanoid, OMA, EggNOG |
Horse | 100059815 | PDGFRA | platelet derived growth factor receptor alpha | 9796 | VGNC:21261 | Inparanoid, OMA, EggNOG |
Cow | 282301 | PDGFRA | platelet derived growth factor receptor alpha | 9913 | VGNC:32692 | Inparanoid, OMA, EggNOG |
Opossum | 100013088 | PDGFRA | platelet derived growth factor receptor alpha | 13616 | | Inparanoid, OMA, EggNOG |
Platypus | 100084432 | PDGFRA | platelet derived growth factor receptor alpha | 9258 | | Inparanoid, OMA, EggNOG |
Chicken | 395509 | PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 9031 | CGNC:10416 | Inparanoid, OMA, EggNOG |
Anole lizard | 100565834 | pdgfra | platelet derived growth factor receptor alpha | 28377 | | Inparanoid, OMA |
Xenopus | 100124862 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | 8364 | XB-GENE-6072920 | Inparanoid, OMA, EggNOG |
Zebrafish | 386856 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | 7955 | ZDB-GENE-990415-208 | Inparanoid, OMA |
Associated Recombinant Proteins
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
Data Source | Name | Explore more targets | Explore in Source |
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