| Description | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
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Gene and Protein Information
| Gene ID | 5290 |
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| Uniprot Accession IDs | Q14CW1 Q99762 PI3-kinase subunit alpha |
| Ensembl ID | ENSP00000263967 |
| Symbol | MCM CWS5 MCAP PI3K CLAPO CLOVE MCMTC PI3K-alpha p110-alpha |
| Family | Belongs to the PI3/PI4-kinase family. |
| Sequence | MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 460858 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9598 | VGNC:7083 | OMA, EggNOG |
| Macaque | 709959 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 18706 | Pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 10090 | MGI:1206581 | Inparanoid, OMA, EggNOG |
| Rat | 170911 | Pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 10116 | RGD:620916 | Inparanoid, OMA |
| Dog | 488084 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9615 | VGNC:44555 | Inparanoid, OMA, EggNOG |
| Horse | 100058141 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9796 | VGNC:21446 | Inparanoid, OMA, EggNOG |
| Cow | 282306 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9913 | VGNC:32889 | Inparanoid, OMA, EggNOG |
| Pig | 100621789 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9823 | OMA, EggNOG | |
| Opossum | 100010412 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:8975] | 9258 | OMA, EggNOG | ||
| Chicken | 424971 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 9031 | CGNC:6785 | Inparanoid, OMA |
| Anole lizard | 100562345 | pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100144924 | pik3ca | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 8364 | XB-GENE-998106 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / transferase / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
protein / kinase / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
protein / transferase / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
protein / kinase / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
DTO Classes
protein / Kinase / Non-protein kinase / Lipid kinase / PI3/PI4 kinase family / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
protein / Kinase / Non-protein kinase / Lipid kinase / PI3/PI4 kinase family / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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