PIK3CA

Description	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Gene and Protein Information

Gene ID	5290
Uniprot Accession IDs	Q14CW1 Q99762 PI3-kinase subunit alpha
Ensembl ID	ENSP00000263967
Symbol	MCM CWS5 MCAP PI3K CLAPO CLOVE MCMTC PI3K-alpha p110-alpha
Family	Belongs to the PI3/PI4-kinase family.
Sequence	MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	460858	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	9598	VGNC:7083	OMA, EggNOG
Macaque	709959	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	9544		Inparanoid, OMA, EggNOG
Mouse	18706	Pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	10090	MGI:1206581	Inparanoid, OMA, EggNOG
Rat	170911	Pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	10116	RGD:620916	Inparanoid, OMA
Dog	488084	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	9615	VGNC:44555	Inparanoid, OMA, EggNOG
Horse	100058141	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	9796	VGNC:21446	Inparanoid, OMA, EggNOG
Cow	282306	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	9913	VGNC:32889	Inparanoid, OMA, EggNOG
Pig	100621789	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	9823		OMA, EggNOG
Opossum	100010412	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	13616		Inparanoid, OMA, EggNOG
Platypus		PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:8975]	9258		OMA, EggNOG
Chicken	424971	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	9031	CGNC:6785	Inparanoid, OMA
Anole lizard	100562345	pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	28377		Inparanoid, OMA, EggNOG
Xenopus	100144924	pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	8364	XB-GENE-998106	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein / transferase / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
protein / kinase / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

DTO Classes
protein / Kinase / Non-protein kinase / Lipid kinase / PI3/PI4 kinase family / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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