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PLK1
| Description | Serine/threonine-protein kinase PLK1 |
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Gene and Protein Information
| Gene ID | 5347 |
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| Uniprot Accession IDs | Q15153 Q99746 |
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| Ensembl ID | ENSP00000300093 |
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| Symbol | PLK PLK STPK13 |
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| Family | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. |
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| Sequence | MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 453991 | PLK1 | polo like kinase 1 | 9598 | VGNC:8992 | Inparanoid, OMA, EggNOG |
| Macaque | 697686 | PLK1 | polo like kinase 1 | 9544 | | Inparanoid, EggNOG |
| Mouse | 18817 | Plk1 | polo like kinase 1 | 10090 | MGI:97621 | Inparanoid, OMA, EggNOG |
| Rat | 25515 | Plk1 | polo-like kinase 1 | 10116 | RGD:3352 | Inparanoid, OMA, EggNOG |
| Dog | 489971 | PLK1 | polo like kinase 1 | 9615 | VGNC:44695 | Inparanoid, OMA, EggNOG |
| Horse | 100068388 | PLK1 | polo like kinase 1 | 9796 | VGNC:21579 | Inparanoid, OMA, EggNOG |
| Cow | 538238 | PLK1 | polo like kinase 1 | 9913 | VGNC:33033 | Inparanoid, OMA, EggNOG |
| Pig | 396953 | PLK1 | polo like kinase 1 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100027403 | PLK1 | polo like kinase 1 | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100073533 | PLK1 | polo like kinase 1 | 9258 | | Inparanoid, OMA, EggNOG |
| Chicken | 416575 | PLK1 | polo like kinase 1 | 9031 | CGNC:4585 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100558384 | plk1 | polo like kinase 1 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 407937 | plk1 | polo like kinase 1 | 8364 | XB-GENE-941540 | Inparanoid, OMA, EggNOG |
| Zebrafish | 280649 | plk1 | polo-like kinase 1 (Drosophila) | 7955 | ZDB-GENE-021115-7 | Inparanoid, OMA, EggNOG |
| C. elegans | 176143 | plk-1 | Serine/threonine-protein kinase plk-1 | 6239 | | OMA, EggNOG |
| C. elegans | 171838 | plk-2 | Serine/threonine-protein kinase plk-2 | 6239 | | Inparanoid, OMA |
| Fruitfly | 40232 | polo | CG12306 gene product from transcript CG12306-RA | 7227 | FBgn0003124 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 855013 | CDC5 | polo kinase CDC5 | 4932 | S000004603 | OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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