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Protein or Target Summary

Serine/threonine-protein kinase PLK1

Gene ID5347
uniprotP53350
Gene NamePLK1
Ensernbl IDENSP00000300093
FamilyBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Sequence
MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN5347PLK1Serine/threonine-protein kinase PLK1P53350
MOUSEPlk1Serine/threonine-protein kinase PLK1A0A0U1RQ54
MOUSEPlk1Serine/threonine-protein kinase PLKQ3UG81
MOUSEPlk1Serine/threonine-protein kinase PLK1A0A0U1RNM9
MOUSE18817Plk1Serine/threonine-protein kinase PLKQ3TPZ2
MOUSE18817Plk1Serine/threonine-protein kinase PLK1Q07832
RATPlk1Serine/threonine-protein kinase PLKA0A140TAD2
RAT25515Plk1Serine/threonine-protein kinase PLK1Q62673

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    Other group    /    PLK family    /    Serine/threonine-protein kinase plk1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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