POLG
| Description | DNA polymerase subunit gamma-1 |
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Gene and Protein Information
| Gene ID | 5428 |
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| Uniprot Accession IDs | Q8NFM2 Q92515 |
| Ensembl ID | ENSP00000268124 |
| Symbol | MDP1 POLG1 POLGA PEO MDP1 SCAE MIRAS POLG1 POLGA SANDO MTDPS4A MTDPS4B |
| Family | Belongs to the DNA polymerase type-A family. |
| Sequence | MSRLLWRKVAGATVGPGPVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLEKRSQPGP Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 467754 | POLG | DNA polymerase gamma, catalytic subunit | 9598 | VGNC:8289 | OMA, EggNOG |
| Macaque | 699750 | POLG | DNA polymerase gamma, catalytic subunit | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 18975 | Polg | polymerase (DNA directed), gamma | 10090 | MGI:1196389 | Inparanoid, OMA, EggNOG |
| Rat | 85472 | Polg | DNA polymerase gamma, catalytic subunit | 10116 | RGD:620057 | Inparanoid, OMA, EggNOG |
| Dog | 100856383 | POLG | DNA polymerase gamma, catalytic subunit | 9615 | VGNC:44781 | Inparanoid, OMA, EggNOG |
| Horse | 100053827 | POLG | DNA polymerase gamma, catalytic subunit | 9796 | VGNC:21659 | Inparanoid, OMA, EggNOG |
| Cow | 533090 | POLG | DNA polymerase gamma, catalytic subunit | 9913 | VGNC:33122 | Inparanoid, OMA, EggNOG |
| Pig | 100157469 | POLG | DNA polymerase gamma, catalytic subunit | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100016380 | POLG | DNA polymerase gamma, catalytic subunit | 13616 | Inparanoid, EggNOG | |
| Chicken | 404292 | POLG | DNA polymerase gamma, catalytic subunit | 9031 | CGNC:49871 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100553734 | polg | DNA polymerase gamma, catalytic subunit | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100488393 | polg | polymerase (DNA) gamma, catalytic subunit | 8364 | XB-GENE-478798 | Inparanoid, OMA, EggNOG |
| Zebrafish | 100150924 | polg | polymerase (DNA directed), gamma | 7955 | ZDB-GENE-060303-1 | Inparanoid, OMA, EggNOG |
| C. elegans | 174860 | polg-1 | POLG (mitochondrial DNA POLymerase Gamma) | 6239 | Inparanoid, OMA, EggNOG | |
| Fruitfly | 34792 | tam | tamas | 7227 | FBgn0004406 | Inparanoid, OMA, EggNOG |
| S.cerevisiae | 854508 | MIP1 | DNA-directed DNA polymerase gamma MIP1 | 4932 | S000005857 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / nucleic acid binding / DNA-directed DNA polymerase / DNA polymerase subunit gamma-1
protein / nucleic acid binding / exodeoxyribonuclease / DNA polymerase subunit gamma-1
protein / nucleic acid binding / nucleotidyltransferase / DNA polymerase subunit gamma-1
protein / nucleic acid binding / nuclease / DNA polymerase subunit gamma-1
protein / nucleic acid binding / DNA-directed DNA polymerase / DNA polymerase subunit gamma-1
protein / nucleic acid binding / exodeoxyribonuclease / DNA polymerase subunit gamma-1
protein / nucleic acid binding / nucleotidyltransferase / DNA polymerase subunit gamma-1
protein / nucleic acid binding / nuclease / DNA polymerase subunit gamma-1
DTO Classes
protein / Enzyme / Transferase / Nucleotidyltransferase / Polymerase / DNA-directed DNA polymerase / DNA polymerase subunit gamma-1
protein / Enzyme / Transferase / Nucleotidyltransferase / Polymerase / DNA-directed DNA polymerase / DNA polymerase subunit gamma-1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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