PDE8A

DescriptionHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

Gene and Protein Information

Gene ID5151
Uniprot Accession IDs B3KXE6 H0YMZ7 Q6P9H3 Q969I1 Q96PC9 Q96PD0 Q96PD1 Q96T71 Q9UMB7 Q9UMC3
Ensembl ID ENSP00000311453
Symbol HsT19550
FamilyBelongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
Sequence
MGCAPSIHISERLVAEDAPSPAAPPLSSGGPRLPQGQKTAALPRTRGAGLLESELRDGSGKKVAVADVQFGPMRFHQDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLDKHHDIIIIDHRNPRQLDAEALCRSIRSSKLSENTVIVGVVRRVDREELSVMPFISAGFTRRYVENPNIMACYNELLQLEFGEVRSQLKLRACNSVFTALENSEDAIEITSEDRFIQYANPAFETTMGYQSGELIGKELGEVPINEKKADLLDTINSCIRIGKEWQGIYYAKKKNGDNIQQNVKIIPVIGQGGKIRHYVSIIRVCNGNNKAEKISECVQSDTHTDNQTGKHKDRRKGSLDVKAVASRATEVSSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQFGAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKNTQMVSSNIITPISLDDVPPRIARAMENEEYWDFDIFELEAATHNRPLIYLGLKMFARFGICEFLHCSESTLRSWLQIIEANYHSSNPYHNSTHSADVLHATAYFLSKERIKETLDPIDEVAALIAATIHDVDHPGRTNSFLCNAGSELAILYNDTAVLESHHAALAFQLTTGDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTKHFEHVNKFVNSINKPLATLEENGETDKNQEVINTMLRTPENRTLIKRMLIKCADVSNPCRPLQYCIEWAARISEEYFSQTDEEKQQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFVDLPDLMQHLDNNFKYWKGLDEMKLRNLRPPPE
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp453612PDE8Aphosphodiesterase 8A9598VGNC:1899OMA, EggNOG
Macaque694750PDE8Aphosphodiesterase 8A9544OMA, EggNOG
Rat308776Pde8aphosphodiesterase 8A10116RGD:735125OMA, EggNOG
Dog488752PDE8Aphosphodiesterase 8A9615VGNC:44365OMA, EggNOG
Horse100068475PDE8Aphosphodiesterase 8A9796VGNC:21256OMA, EggNOG
Cow506787PDE8Aphosphodiesterase 8A9913VGNC:32687OMA, EggNOG
Anole lizard100557720LOC100557720high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A28377OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source