PDGFRB

DescriptionPlatelet-derived growth factor receptor beta

Gene and Protein Information

Gene ID5159
Uniprot Accession IDs B5A957 Q8N5L4 PDGF-R-beta
Ensembl ID ENSP00000261799
Symbol PDGFR PDGFR1 IMF1 KOGS IBGC4 JTK12 PDGFR PENTT CD140B PDGFR1 PDGFR-1
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Sequence
MRLPGAMPALALKGELLLLSLLLLLEPQISQGLVVTPPGPELVLNVSSTFVLTCSGSAPVVWERMSQEPPQEMAKAQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVALPVPYDHQRGFSGIFEDRSYICKTTIGDREVDSDAYYVYRLQVSSINVSVNAVQTVVRQGENITLMCIVIGNEVVNFEWTYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSAELEDSGTYTCNVTESVNDHQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPPTVLWFKDNRTLGDSSAGEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVLELSESHPDSGEQTVRCRGRGMPQPNIIWSACRDLKRCPRELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRNAVGQDTQEVIVVPHSLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNTSSTISCDSPLEPQDEPEPEPQLELQVEPEPELEQLPDSGCPAPRAEAEDSFL
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque711353PDGFRBplatelet derived growth factor receptor beta9544Inparanoid, OMA, EggNOG
Mouse18596Pdgfrbplatelet derived growth factor receptor, beta polypeptide10090MGI:97531Inparanoid, OMA, EggNOG
Rat24629Pdgfrbplatelet derived growth factor receptor beta10116RGD:3285Inparanoid, OMA, EggNOG
Dog442985PDGFRBplatelet derived growth factor receptor beta9615VGNC:44373Inparanoid, OMA, EggNOG
Horse100071665PDGFRBplatelet derived growth factor receptor beta9796VGNC:21262Inparanoid, OMA, EggNOG
Cow527165PDGFRBplatelet derived growth factor receptor beta9913VGNC:32693Inparanoid, OMA, EggNOG
Opossum100028943PDGFRBplatelet derived growth factor receptor beta13616Inparanoid, EggNOG
PlatypusPDGFRBplatelet derived growth factor receptor beta [Source:HGNC Symbol;Acc:HGNC:8804]9258OMA, EggNOG
Anole lizard100555784pdgfrbplatelet derived growth factor receptor beta28377Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    PDGFR family    /    Platelet-derived growth factor receptor beta

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source